Isolated Subtle Neurological Abnormalities in Mild Cognitive Impairment Types

Background: Isolated, subtle neurological abnormalities (ISNA) are commonly seen in aging and have been related to cerebral small vessel disease (SVD) and subcortical atrophy in neurologically and cognitively healthy aging subjects. Objective: To investigate the frequency of ISNA in different mild cognitive impairment (MCI) types and to evaluate for each MCI type, the crosssectional relation between ISNA and white matter hyperintensities (WMH), lacunes, caudate atrophy, and ventricular enlargement. Methods: One thousand two hundred fifty subjects with different MCI types were included in the analysis and underwent brain magnetic resonance imaging. WMHs were assessed through two visual rating scales. Lacunes were also rated. Atrophy of the caudate nuclei and ventricular enlargement were assessed through the bicaudate ratio (BCr) and the lateral ventricles to brain ratio (LVBr), respectively. Apolipoprotein E (APOE) genotypes were also assessed. The routine neurological examination was used to evaluate ISNAs that were clustered as central-based signs, cerebellar-based signs, and primitive reflexes. The items of Part-III of the Unified Parkinson’s Disease Rating Scale were used to evaluate ISNAs that were clustered as mild parkinsonian signs. Associations of ISNAs with imaging findings were determined through logistic regression analysis. Results: The ISNAs increase with the age and are present in all MCI types, particularly in those multiple domains, and carrying the APOE ϵ4 allele, and are associated with WMH, lacunes, BCr, and LVBr. Conclusion: This study demonstrates that cortical and subcortical vascular and atrophic processes contribute to ISNAs. Long prospective population-based studies are needed to disentangle the role of ISNAs in the conversion from MCI to dementia

A survey on the soundscape perception before and during the COVID-19 pandemic in Italy

Abstract At the time of the COVID-19 pandemic, the impact of lockdown measures highlights changes in terms of sounds and noises present in the everyday life. The present paper deals with this peculiar and unexpected scenario as studied by means of an online survey consisting of 18 questions and distributed to residents in the Italian territory. For studying the unprecedented effect of the pandemic, participants were asked to fill the questionnaire, providing personal data, describing context and characteristics of the house in which they live and making a comparison of the lockdown soundscape with the pre-lockdown one. About four hundred questionnaires have been collected and analysed in order to define correlations between personal and perception variables. Using logistic regression models, changes have been studied during the two abovementioned periods. It has been observed that the perception of traffic noise has increased for people over 35 years old and the noise produced by the neighbourhood has been more statistically significant for employed respondents. Future outlook might provide the spread of the questionnaire in other countries for a global evaluation of the data, to be also acquired with reference to the after-lockdown period

Un aporte para la reconstrucción de las memorias feministas de la primera mitad de la década de los setenta, en Argentina

En el presente trabajo nos proponemos contribuir a la construcción de las memorias feministas de los años setenta. Ante las dificultades que se presentan a la hora de reconstruir la historia del feminismo de los setenta, surge la necesidad de impulsar la reconstrucción de sus memorias con nuevos y heterodoxos métodos de abordaje. En este caso ensayaremos la posibilidad de producir un relato de sí, una historia de vida, a partir de una lectura un archivo personal, el de Sara Torres ex militante de la Unión Feminista Argentina (UFA). En la elaboración de las historias que se desprenden del archivo analizamos críticamente la bibliografía existente sobre el feminismo en cuestión al tiempo que propondremos nuevas coordenadas para el análisis de dicha experiencia militante.Fil: Trebisacce, Catalina Paola. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Torelli, María Luz. Universidad de Buenos Aires; Argentin

Un aporte para la reconstrucción de las memorias feministas de la primera mitad de la década de los setenta, en Argentina

En el presente trabajo nos proponemos contribuir a la construcción de las memorias feministas de los años setenta. Ante las dificultades que se presentan a la hora de reconstruir la historia del feminismo de los setenta, surge la necesidad de impulsar la reconstrucción de sus memorias con nuevos y heterodoxos métodos de abordaje. En este caso ensayaremos la posibilidad de producir un relato de sí, una historia de vida, a partir de una lectura un archivo personal, el de Sara Torres ex militante de la Unión Feminista Argentina (UFA). En la elaboración de las historias que se desprenden del archivo analizamos críticamente la bibliografía existente sobre el feminismo en cuestión al tiempo que propondremos nuevas coordenadas para el análisis de dicha experiencia militante.Fil: Trebisacce, Catalina Paola. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Torelli, María Luz. Universidad de Buenos Aires; Argentin

Caught while Dissolving: Revealing the Interfacial Solvation of the Mg2+ Ions on the MgO Surface

Interfaces between water and materials are ubiquitous and are crucial in materials sciences and in biology, where investigating the interaction of water with the surface under ambient conditions is key to shedding light on the main processes occurring at the interface. Magnesium oxide is a popular model system to study the metal oxide-water interface, where, for sufficient water loadings, theoretical models have suggested that reconstructed surfaces involving hydrated Mg2+ metal ions may be energetically favored. In this work, by combining experimental and theoretical surface-selective ambient pressure X-ray absorption spectroscopy with multivariate curve resolution and molecular dynamics, we evidence in real time the occurrence of Mg2+ solvation at the interphase between MgO and solvating media such as water and methanol (MeOH). Further, we show that the Mg2+ surface ions undergo a reversible solvation process, we prove the dissolution/redeposition of the Mg2+ ions belonging to the MgO surface, and we demonstrate the formation of octahedral [Mg(H2O)6]2+ and [Mg(MeOH)6]2+ intermediate solvated species. The unique surface, electronic, and structural sensitivity of the developed technique may be beneficial to access often elusive properties of low-Z metal ion intermediates involved in interfacial processes of chemical and biological interest

Memorias feministas, ni escritas ni contadas: guardadas. Metiendo las narices en el archivo personal de una feminista argentina de los años setenta

El conocimiento de la existencia de militancia feminista en la Argentina en los años setenta representa, actualmente, una información de circulación restringida en el campo de las ciencias sociales. Las razones de esta situación estriban en múltiples causas, entre las cuales resaltan la falta de interés y/o subestimación del tema desde la comunidad científica y el empleo de una metodología inapropiada para su investigación. El presente trabajo, inscripto en el marco de los estudios de memorias, propone la construcción de una metodología específica para su abordaje y análisis. Asimismo, existe una acotada producción historiográfica que buscó estudiar aquel feminismo empleando parámetros y metodologías habitualmente aplicados al estudio de la militancia protagónica del período, la nueva izquierda. Será parte central de nuestro trabajo discutir las interpretaciones derivadas de estos estudios, específicamente en lo que respecta al análisis, y/o a su ausencia, del entrecruzamiento acontecido entre radicalización política y modernización cultural. Entrecruzamiento que impactó de muy distinta manera en la nueva izquierda y el feminismo. El fin será evidenciar la especificidad aún no retratada de la militancia feminista de entonces.The awareness of the existence of feminist militancy in Argentina during the seventies has a restricted circulation within the field of social sciences. The reasons for this situation are multiple, amongst which stand out the scientific community’s underestimation of this topic and /or lack of interest in it, and the inaccurate methodology used for its investigation. This work, which is framed under the theory of memory studies, suggests the construction of a specific methodology for its approach and analysis. Also, there is a limited historiographical production that intended to study this feminism using parameters and methodologies usually employed to investigate the preeminent militancy of the period, the new left. As a central part of our work, we’ll discuss the interpretations derived from these studies, specifically the analysis, or lack of, of the crossing that took place between political radicalization and cultural modernization. This crossing had a very different impact in the new left and feminism. Our goal is to show the, yet to be portrayed, specificity of feminist militancy in those years.Fil: Trebisacce, Catalina Paola. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto Interdisciplinario de Estudios de Género; ArgentinaFil: Torelli, María Luz. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto Interdisciplinario de Estudios de Género; Argentin

A renewed perception of living environments after restrictions due to pandemic in Italy

Abstract The rapid habitual changes induced by the emergence of the COVID-19 pandemic first and the end of the most restrictive phase coinciding with the lock-down later resulted in significant changes, also occurred at an environmental level and, specifically, with regard to the perception of the soundscape in all European countries. The seek for knowledge underlying the research illustrated in this article concerned whether or not the perception of the soundscape following the almost normal resumption of daily activities had returned to that of the period before the restrictions came into force. This article illustrates how an online questionnaire structured in 16 questions was designed and administered to a sample of Italian citizens, in order to understand whether and how the habits of the respondents had changed in the three reference time periods (before the pandemic spread, the period marked by lock-down or other restrictions in early 2020 and the period afterwards) and their perception of the perceived soundscape of the place where they spend most of their days. A total of around 70 questionnaires distributed throughout Italy were collected and analysed. The results obtained, through the use of descriptive statistical analyses and logistic models, are also presented in this article

Early Recovery of Aphasia through Thrombolysis: The Significance of Spontaneous Speech

Aphasia in one of the most devastating stroke-related consequences for social interaction and daily activities. Aphasia recovery in acute stroke depends on the degree of reperfusion after thrombolysis or thrombectomy. As aphasia assessment tests are often time-consuming for patients with acute troke, physicians have been developing rapid and simple tests. The aim of our study is to evaluate the improvement of language functions in the earliest stage in patients treated with thrombolysis and in nontreated patients using our rapid screening tes