Síndrome de Burnout : relações com comprometimento afetivo entre gestores de organização estatal

Esta pesquisa envolveu dois conceitos centrais e a tentativa de articulá-los teórica e empiricamente: síndrome de burnout e comprometimento organizacional afetivo. Foram aplicados 249 questionários, contendo escalas padronizadas de cinco pontos, tipo Likert, e realizadas 16 entrevistas, apoiadas em roteiros semi-estruturados, entre gestores da Eletronorte. Formulou- se a hipótese de que os respondentes apresentariam comportamentos típicos de burnout e de que haveria uma relação positiva entre esta variável e comprometimento afetivo. Foram realizadas análises inferenciais e identificou- se, entre os respondentes, nível moderado de burnout nos fatores exaustão emocional, despersonalização e baixa realização pessoal, sendo que 27,7% dos pesquisados apresentaram índices altos ou moderados nos três fatores da síndrome, predominando o fator baixa realização pessoal; 61,8% e 36,14% dos respondentes apresentaram níveis elevado e moderado, respectivamente, de comprometimento afetivo. A hipótese foi confirmada quanto à presença de burnout e rejeitada no que se refere à relação positiva entre a síndrome e comprometimento. Os resultados podem ser úteis para a compreensão de fenômenos pouco explorados no campo do comportamento organizacional, em especial entre gestores que atuam em organizações em fase de transformação. _____________________________________________________________________________________________________________ ABSTRACTThis research encompasses two main concepts and aimed to analyse them both theoretical and empirically: burnout syndrome and affective organisational commitment. 249 five-point standardised Likert-scale questionnaires were filled out and 16 interviews, supported by semi-structured schedules were undertaken with Eletronorte managers. The research hypothesis was 159 that these managers would have typical burnout behaviour and a positive relationship between this syndrome and attitudinal commitment would be find. Inferential analyses were done and medium level of burnout syndrome on the emotional exhaustion, depersonalisation and low personal accomplishment were identified. 27,7% of the managers presented medium or high levels on the three syndrome factors, stressing the low personal accomplishment factor; 61,8% and 36,14% of the research participants showed high and medium levels, respectively, of attitudinal commitment. The hypothesis was accepted upon the burnout syndrome, but rejected on the positive relationship between that syndrome and commitment. The results can be useful to understand factors less explored on the organisational behaviour field, especially amongst managers that work on organisations which are on changing process

De consolatione philosophiae ; De disciplina scholarium

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Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality