Optimal receptor-cluster size determined by intrinsic and extrinsic noise

Biological cells sense external chemical stimuli in their environment using cell-surface receptors. To increase the sensitivity of sensing, receptors often cluster, most noticeably in bacterial chemotaxis, a paradigm for signaling and sensing in general. While amplification of weak stimuli is useful in absence of noise, its usefulness is less clear in presence of extrinsic input noise and intrinsic signaling noise. Here, exemplified on bacterial chemotaxis, we combine the allosteric Monod-Wyman- Changeux model for signal amplification by receptor complexes with calculations of noise to study their interconnectedness. Importantly, we calculate the signal-to-noise ratio, describing the balance of beneficial and detrimental effects of clustering for the cell. Interestingly, we find that there is no advantage for the cell to build receptor complexes for noisy input stimuli in absence of intrinsic signaling noise. However, with intrinsic noise, an optimal complex size arises in line with estimates of the sizes of chemoreceptor complexes in bacteria and protein aggregates in lipid rafts of eukaryotic cells.Comment: 15 pages, 12 figures,accepted for publication on Physical Review

Cherenkov radiation by particles traversing the background radiatio n

High energy particles traversing the Universe through the cosmic microwave backgroung radiation can, in principle, emit Cherenkov radiation. It is shown that the energy threshold for this radiation is extremely high and its intensity would be too low due to the low density of the "relic photons gas" and very weak interaction of two photons.Comment: 6 pages, LATEX, no Figs.; to be published in JETP Lett. 75 (N4) (2002

Two-photon final states in peripheral heavy ion collisions

We discuss processes leading to two photon final states in peripheral heavy ion collisions at RHIC. Due to the large photon luminosity we show that the continuum subprocess $\gamma \gamma \to \gamma \gamma$ can be observed with a large number of events. We study this reaction when it is intermediated by a resonance made of quarks or gluons and discuss its interplay with the continuum process, verifying that in several cases the resonant process ovewhelms the continuum one. It is also investigated the possibility of observing a scalar resonance (the $\sigma$ meson) in this process. Assuming for the $\sigma$ the mass and total decay width values recently reported by the E791 Collaboration we show that RHIC may detect this particle in its two photon decay mode if its partial photonic decay width is of the order of the ones discussed in the literature.Comment: 10 pages, 8 figure

Josephson current in a superconductor-ferromagnet junction with two non-collinear magnetic domains

We study the Josephson effect in a superconductor--ferromagnet--superconductor (SFS) junction with ferromagnetic domains of non-collinear magnetization. As a model for our study we consider a diffusive junction with two ferromagnetic domains along the junction. The superconductor is assumed to be close to the critical temperature $T_c$, and the linearized Usadel equations predict a sinusoidal current-phase relation. We find analytically the critical current as a function of domain lengths and of the angle between the orientations of their magnetizations. As a function of those parameters, the junction may undergo transitions between 0 and $\pi$ phases. We find that the presence of domains reduces the range of junction lengths at which the $\pi$ phase is observed. For the junction with two domains of the same length, the $\pi$ phase totally disappears as soon as the misorientation angle exceeds $\pi/2$. We further comment on possible implication of our results for experimentally observable 0--$\pi$ transitions in SFS junctions.Comment: 9 pages, 4 figures, minor changes, references adde

Generation of Cosmological Seed Magnetic Fields from Inflation with Cutoff

Inflation has the potential to seed the galactic magnetic fields observed today. However, there is an obstacle to the amplification of the quantum fluctuations of the electromagnetic field during inflation: namely the conformal invariance of electromagnetic theory on a conformally flat underlying geometry. As the existence of a preferred minimal length breaks the conformal invariance of the background geometry, it is plausible that this effect could generate some electromagnetic field amplification. We show that this scenario is equivalent to endowing the photon with a large negative mass during inflation. This effective mass is negligibly small in a radiation and matter dominated universe. Depending on the value of the free parameter of the theory, we show that the seed required by the dynamo mechanism can be generated. We also show that this mechanism can produce the requisite galactic magnetic field without resorting to a dynamo mechanism.Comment: Latex, 16 pages, 2 figures, 4 references added, minor corrections; v4: more references added, boundary term written in a covariant form, discussion regarding other gauge fields added, submitted to PRD; v5: matched with the published versio

Probing For New Physics and Detecting non linear vacuum QED effects using gravitational wave interferometer antennas

Low energy non linear QED effects in vacuum have been predicted since 1936 and have been subject of research for many decades. Two main schemes have been proposed for such a 'first' detection: measurements of ellipticity acquired by a linearly polarized beam of light passing through a magnetic field and direct light-light scattering. The study of the propagation of light through an external field can also be used to probe for new physics such as the existence of axion-like particles and millicharged particles. Their existence in nature would cause the index of refraction of vacuum to be different from unity in the presence of an external field and dependent of the polarization direction of the light propagating. The major achievement of reaching the project sensitivities in gravitational wave interferometers such as LIGO an VIRGO has opened the possibility of using such instruments for the detection of QED corrections in electrodynamics and for probing new physics at very low energies. In this paper we discuss the difference between direct birefringence measurements and index of refraction measurements. We propose an almost parasitic implementation of an external magnetic field along the arms of the VIRGO interferometer and discuss the advantage of this choice in comparison to a previously proposed configuration based on shorter prototype interferometers which we believe is inadequate. Considering the design sensitivity in the strain, for the near future VIRGO+ interferometer, of $h<2\cdot10^{-23} \frac{1}{\sqrt{\rm Hz}}$ in the range 40 Hz $- 400$ Hz leads to a variable dipole magnet configuration at a frequency above 20 Hz such that $B^{2}D \ge 13000$ T$^{2}$m/$\sqrt{\rm Hz}$ for a `first' vacuum non linear QED detection

Elastic and Raman scattering of 9.0 and 11.4 MeV photons from Au, Dy and In

Monoenergetic photons between 8.8 and 11.4 MeV were scattered elastically and in elastically (Raman) from natural targets of Au, Dy and In.15 new cross sections were measured. Evidence is presented for a slight deformation in the 197Au nucleus, generally believed to be spherical. It is predicted, on the basis of these measurements, that the Giant Dipole Resonance of Dy is very similar to that of 160Gd. A narrow isolated resonance at 9.0 MeV is observed in In.Comment: 31 pages, 11 figure

On the pion electroproduction amplitude

We analyze amplitudes for the pion electroproduction on proton derived from Lagrangians based on the local chiral SU(2) x SU(2) symmetries. We show that such amplitudes do contain information on the nucleon axial form factor F_A in both soft and hard pion regimes. This result invalidates recent Haberzettl's claim that the pion electroproduction at threshold cannot be used to extract any information regarding F_A.Comment: 14 pages, 6 figures, revised version, accepted for publication in Phys. Rev.