14 research outputs found
Enhancement strategies for transdermal drug delivery systems: current trends and applications
Cationic Polymethacrylate-Modified Liposomes Significantly Enhanced Doxorubicin Delivery and Antitumor Activity
Effect of nanoparticles on the therapeutic efficacy of praziquantel against Schistosoma mansoni infection in murine models
Quantitative Methods for Investigating Dissociation of Fluorescently Labeled Lipids from Drug Delivery Liposomes
Nanotechnology and Drug Delivery
Nowadays nanotechnology represents an expanding field that is providing powerfultools for the pharmaceutical industry such as polymeric, solid lipid, metallic, and magnetic NPs, liposomes, dendrimers, and other nanostructures. The development of nanopharmaceutics allows the understanding of some of the major mechanisms of current diseases on a molecular basis. Particularly, drug delivery mediated by nanosystems is relevant since NPs are able to reach the target organ and deliver the drug with a desirable profile according to the pathology needs, minimizing undesirable side effects. The main physicochemical properties of nanosystems are related with the increase in the surface-to-volume ratio of the particles, their permeability across biological barriers, and the surface modification of nanodevices. These parameters are relevant in drug loading and release and particularly for the targeted delivery to cells showing specific markers or receptors in the membrane surface.Fil: Islan, German Abel. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata. Centro de InvestigaciĂłn y Desarrollo en Fermentaciones Industriales. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de InvestigaciĂłn y Desarrollo en Fermentaciones Industriales; ArgentinaFil: Martin Saldaña, Sergio. Gihon Laboratorios QuĂmicos SRL; ArgentinaFil: Chevalier, Merari Tumin. Gihon Laboratorios QuĂmicos SRL; ArgentinaFil: Alvarez, Vera Alejandra. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y TecnologĂa de Materiales. Universidad Nacional de Mar del Plata. Facultad de IngenierĂa. Instituto de Investigaciones en Ciencia y TecnologĂa de Materiales; ArgentinaFil: Castro, Guillermo Raul. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata. Centro de InvestigaciĂłn y Desarrollo en Fermentaciones Industriales. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de InvestigaciĂłn y Desarrollo en Fermentaciones Industriales; Argentin