1,296 research outputs found

    Toward Hybrid Materials: Group Transfer Polymerization of 3-(Trimethoxysilyl)propyl Methacrylate

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    Front Cover: Group transfer polymerisation (GTP), a living polymerization technique that is easy to scale up, enables the one-pot fabrication of class-II hybrid materials. Specifically a star polymer is synthesized with a 3-(trimethoxy-silyl)propyl methacrylate, alkoxysilane group containing functional monomer. The polymer is then cross-linked to produce an organic-inorganic class-II hybrid material, which can be used in various applications such as thin films and biomaterials. Further details can be found in the article by J. J. Chung, J. R. Jones, and T. K. Georgiou* on page 1806

    Music reading expertise modulates visual spans in both music note and English letter reading

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    Poster Session 3: no. 73Conference Theme: Integrating Psychological, Philosophical, Linguistic, Computational and Neural PerspectivesHere we investigated how music reading experience modulates visual spans in language reading. Participants were asked to identify music notes, English letters, Chinese characters, and novel symbols (Tibetan letters) presented at random locations on the screen while maintaining central fixation. We found that for music note reading, musicians outperformed non-musicians at some peripheral positions in both visual fields, and for English letter reading, musicians outperformed non-musicians at some peripheral positions in the RVF but not in the LVF. In contrast, in both Chinese character and novel symbol reading, musicians and non-musicians did not differ in their performance at peripheral positions. Since both music and English reading involve a left-to-right reading direction and a RVF/LH advantage, these results suggest that the modulation of music reading experience on visual spans in language reading depends on the similarities in the cognitive processes involved.postprin

    SIMP (Strongly Interacting Massive Particle) Search

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    We consider laboratory experiments that can detect stable, neutral strongly interacting massive particles (SIMPs). We explore the SIMP annihilation cross section from its minimum value (restricted by cosmological bounds) to the barn range, and vary the mass values from a GeV to a TeV. We also consider the prospects and problems of detecting such particles at the Tevatron.Comment: Latex. 7 pages, 1 eps figure. Proceedings to the 4th UCLA Symposium on Dark Matter DM2000, Marina del Rey, CA, USA, Feb. 23-25, 200

    Maintenance techniques for rechargeable battery using pulse charging

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    Author name used in this publication: Cheng K. W. E.Author name used in this publication: Ho Y. L.Refereed conference paper2006-2007 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

    POCS-based reconstruction of multiplexed sensitivity encoded MRI (POCSMUSE): A general algorithm for reducing motion-related artifacts.

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    PURPOSE: A projection onto convex sets reconstruction of multiplexed sensitivity encoded MRI (POCSMUSE) is developed to reduce motion-related artifacts, including respiration artifacts in abdominal imaging and aliasing artifacts in interleaved diffusion-weighted imaging. THEORY: Images with reduced artifacts are reconstructed with an iterative projection onto convex sets (POCS) procedure that uses the coil sensitivity profile as a constraint. This method can be applied to data obtained with different pulse sequences and k-space trajectories. In addition, various constraints can be incorporated to stabilize the reconstruction of ill-conditioned matrices. METHODS: The POCSMUSE technique was applied to abdominal fast spin-echo imaging data, and its effectiveness in respiratory-triggered scans was evaluated. The POCSMUSE method was also applied to reduce aliasing artifacts due to shot-to-shot phase variations in interleaved diffusion-weighted imaging data corresponding to different k-space trajectories and matrix condition numbers. RESULTS: Experimental results show that the POCSMUSE technique can effectively reduce motion-related artifacts in data obtained with different pulse sequences, k-space trajectories and contrasts. CONCLUSION: POCSMUSE is a general post-processing algorithm for reduction of motion-related artifacts. It is compatible with different pulse sequences, and can also be used to further reduce residual artifacts in data produced by existing motion artifact reduction methods

    Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT) -I/II null mutant mice

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    <p>Abstract</p> <p>Background</p> <p>Metallothionein-I and -II (MT-I/II) is produced by reactive astrocytes in the injured brain and has been shown to have neuroprotective effects. The neuroprotective effects of MT-I/II can be replicated <it>in vitro </it>which suggests that MT-I/II may act directly on injured neurons. However, MT-I/II is also known to modulate the immune system and inflammatory processes mediated by the immune system can exacerbate brain injury. The present study tests the hypothesis that MT-I/II may have an indirect neuroprotective action via modulation of the immune system.</p> <p>Methods</p> <p>Wild type and MT-I/II<sup>-/- </sup>mice were administered cryolesion brain injury and the progression of brain injury was compared by immunohistochemistry and quantitative reverse-transcriptase PCR. The levels of circulating leukocytes in the two strains were compared by flow cytometry and plasma cytokines were assayed by immunoassay.</p> <p>Results</p> <p>Comparison of MT-I/II<sup>-/- </sup>mice with wild type controls following cryolesion brain injury revealed that the MT-I/II<sup>-/- </sup>mice only showed increased rates of neuron death after 7 days post-injury (DPI). This coincided with increases in numbers of T cells in the injury site, increased IL-2 levels in plasma and increased circulating leukocyte numbers in MT-I/II<sup>-/- </sup>mice which were only significant at 7 DPI relative to wild type mice. Examination of mRNA for the marker of alternatively activated macrophages, Ym1, revealed a decreased expression level in circulating monocytes and brain of MT-I/II<sup>-/- </sup>mice that was independent of brain injury.</p> <p>Conclusions</p> <p>These results contribute to the evidence that MT-I/II<sup>-/- </sup>mice have altered immune system function and provide a new hypothesis that this alteration is partly responsible for the differences observed in MT-I/II<sup>-/- </sup>mice after brain injury relative to wild type mice.</p

    Experimental verification of electrostatic boundary conditions in gate-patterned quantum devices

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    In a model of a gate-patterned quantum device it is important to choose the correct electrostatic boundary conditions (BCs) in order to match experiment. In this study, we model gated-patterned devices in doped and undoped GaAs heterostructures for a variety of BCs. The best match is obtained for an unconstrained surface between the gates, with a dielectric region above it and a frozen layer of surface charge, together with a very deep back boundary. Experimentally, we find a 0.2V offset in pinch-off characteristics of one-dimensional channels in a doped heterostructure before and after etching off a ZnO overlayer, as predicted by the model. Also, we observe a clear quantised current driven by a surface acoustic wave through a lateral induced n-i-n junction in an undoped heterostructure. In the model, the ability to pump electrons in this type of device is highly sensitive to the back BC. Using the improved boundary conditions, it is straightforward to model quantum devices quite accurately using standard software
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