10,116 research outputs found

    Pre-litigation Mediation as a Privacy Policy: Exploring the Interaction of Economics and Privacy

    Get PDF
    Pre-litigation mediation is a perfect example of the economic trade-offs that exist in privacy policy. In pre-litigation mediation, costs and confidentiality work independently. However, there is a precarious balance that exists where, if either confidentiality or cost became less effective the entire mediation process might be damaged.mediation; confidentiality, privacy, prelitigation; prelitigation mediation

    Understanding the Devil: A Comparative Examination of Dead Souls, The Master and Margarita, and Revelation 12-3

    Get PDF
    This thesis examines how the devil is depcicted and characterized in Nikolai Gogol\u27s Dead Souls, Mikhail Bulgakov\u27s The Master and Margarita, and Revelation 12-13. By exploring their respective historical situations, I connect how all three depictions are linked to satire; however, I reflect upon the differences between the literary and religious, most notably the grotesque physical portrayals and allusory nature of Revelation. The three texts are given their own sections, each divided into three parts: historical situation, textual analysis, and literary commentary. From this analysis, it is shown that the devil carries with them a history of sins within great societies and within individual humans. It is through understanding the literary devil that the power of these sins can be understood, and by studying the literature, there is hope that we can recognize and be ready for when the devil returns to society

    The prevalence of primary headache disorders in Ethiopia

    Get PDF
    BACKGROUND: Knowledge of the epidemiology of primary headache disorders in sub-Saharan Africa (SSA) remains very limited. We performed a population-based survey in rural and urban areas of Ethiopia, using methods similar to those of an earlier study in Zambia and tested in multiple other countries by Lifting The Burden. METHODS: In a cross-sectional survey we visited households unannounced in four regions of Ethiopia: the mostly urban populations in Addis Ababa and its environs and rural populations of selected districts in Oromia, Amhara and South Nations Nationalities and People's Regions States (SNNPRS). We used cluster-randomized sampling: within clusters we randomly selected households, and one adult member (18-65 years old) of each household. The HARDSHIP structured questionnaire, translated into the local languages, was administered face-to-face by trained interviewers. Demographic enquiry was followed by diagnostic questions based on ICHD-II criteria. RESULTS: From 2,528 households approached, 2,385 of 2,391 eligible members (1,064 [44.7%] male, 596 [25.0%] urban) consented to interview (participating proportion 99.8%). Headache in the preceding year was reported by 1,071 participants (44.9% [95% CI: 42.4-46.3]; males 37.7%, females 49.9%), and headache yesterday by 170 (7.1% [6.2-8.2]; males 45 [4.1%], females 125 [9.2%]). Adjusted for gender, age and habitation (urban/rural), 1-year prevalence of migraine was 17.7%, of tension-type headache (TTH) 20.6%, of all headache on ≥15 days/month 3.2%, and of probable medication-overuse headache (pMOH) 0.7%. The adjusted prevalence of headache yesterday was 6.4%. Very few cases (1.6%) were unclassifiable. All headache disorders were more common in females. TTH was less common in urban areas (OR: 0.3; p < 0.0001), but pMOH was very strongly associated (OR: 6.1; p < 0.0001) with urban dwelling. Education was negatively associated with migraine (OR: 0.5-0.7; p < 0.05) but (at university level) positively with pMOH (OR: 2.9; p = 0.067). Income above ETB 500/month showed similar associations: negatively with migraine (OR: 0.8; p = 0.035), positively with pMOH (OR: 2.1; p = 0.164). CONCLUSIONS: Findings for migraine and TTH in Ethiopia were quite similar to those from Zambia, another SSA country; pMOH was much less prevalent but, as in Zambia, essentially an urban problem. Primary headache disorders are at least as prevalent in SSA as in high-income western countries

    An investigation into the effects of excluding the catch phase of the power clean on force-time characteristics during isometric and dynamic tasks

    Get PDF
    The aims of this study were to compare the effects of the exclusion or inclusion of the catch phase during power clean (PC) derivatives on force-time characteristics during isometric and dynamic tasks, after two 4-week mesocycles of resistance training. Two strength matched groups completed the twice-weekly training sessions either including the catch phase of the PC derivatives (Catch group: n = 16; age 19.3 ± 2.1 years; height 1.79 ± 0.08 m; body mass 71.14 ± 11.79 kg; PC 1 repetition maximum [1RM] 0.93 ± 0.15 kg·kg-1) or excluding the catch phase (Pull group: n = 18; age 19.8 ± 2.5 years; height 1.73 ± 0.10 m; body mass 66.43 ± 10.13 kg; PC 1RM 0.91 ± 0.18 kg·kg-1). The Catch and Pull groups both demonstrated significant (p ≤ 0.007, power ≥0.834) and meaningful improvements in countermovement jump height (10.8 ± 12.3%, 5.2 ± 9.2%), isometric mid-thigh pull performance (force [F]100: 14.9 ± 17.2%, 15.5 ± 16.0%, F150: 16.0 ± 17.6%, 16.2 ± 18.4%, F200: 15.8 ± 17.6%, 17.9 ± 18.3%, F250: 10.0 ± 16.1%,10.9 ± 14.4%, peak force: 13.7 ± 18.7%, 9.7 ± 16.3%), and PC 1RM (9.5 ± 6.2%, 8.4 ± 6.1%), before and after intervention, respectively. In contrast to the hypotheses, there were no meaningful or significant differences in the percentage change for any variables between groups. This study clearly demonstrates that neither the inclusion nor exclusion of the catch phase of the PC derivatives results in any preferential adaptations over two 4-week, in-season strength and power, mesocycles

    Prescription Drugs Associated with Reports of Violence Towards Others

    Get PDF
    CONTEXT: Violence towards others is a seldom-studied adverse drug event and an atypical one because the risk of injury extends to others. OBJECTIVE: To identify the primary suspects in adverse drug event reports describing thoughts or acts of violence towards others, and assess the strength of the association. METHODOLOGY: From the Food and Drug Administration (FDA) Adverse Event Reporting System (AERS) data, we extracted all serious adverse event reports for drugs with 200 or more cases received from 2004 through September 2009. We identified any case report indicating homicide, homicidal ideation, physical assault, physical abuse or violence related symptoms. MAIN OUTCOME MEASURES: Disproportionality in reporting was defined as a) 5 or more violence case reports, b) at least twice the number of reports expected given the volume of overall reports for that drug, c) a χ2 statistic indicating the violence cases were unlikely to have occurred by chance (p<0.01). RESULTS: We identified 1527 cases of violence disproportionally reported for 31 drugs. Primary suspect drugs included varenicline (an aid to smoking cessation), 11 antidepressants, 6 sedative/hypnotics and 3 drugs for attention deficit hyperactivity disorder. The evidence of an association was weaker and mixed for antipsychotic drugs and absent for all but 1 anticonvulsant/mood stabilizer. Two or fewer violence cases were reported for 435/484 (84.7%) of all evaluable drugs suggesting that an association with this adverse event is unlikely for these drugs. CONCLUSIONS: Acts of violence towards others are a genuine and serious adverse drug event associated with a relatively small group of drugs. Varenicline, which increases the availability of dopamine, and antidepressants with serotonergic effects were the most strongly and consistently implicated drugs. Prospective studies to evaluate systematically this side effect are needed to establish the incidence, confirm differences among drugs and identify additional common features

    Changes in dynamic strength index in response to strength training

    Get PDF
    The primary aim of this investigation was to determine the effects of a four-week period of in-season strength training on the dynamic strength index (DSI). Pre and post a four-week period of strength-based training, twenty-four collegiate athletes (age = 19.9 ± 1.3 years; height = 1.70 ± 0.11 m; weight 68.1 ± 11.8 kg) performed three isometric mid-thigh pulls and countermovement jumps to permit the calculation of DSI. T-tests and Cohen’s effect sizes revealed a significant but small (p = 0.009, d = 0.50) decrease in DSI post-training (0.71 ± 0.13 N·N−1) compared to pre-training (0.65 ± 0.11 N·N−1); however, when divided into high and low DSI groups, differential responses were clear. The low DSI group exhibited no significant or meaningful (p = 1.000, d = 0.00) change in DSI pre to post-training (0.56 ± 0.05 N·N−1, 0.56 ± 0.09 N·N−1, respectively), whereas the high DSI group demonstrated a significant and large decrease (p = 0.034, d = 1.29) in DSI pre to post-training (0.85 ± 0.05 N·N−1, 0.74 ± 0.11 N·N−1, respectively), resulting in a significant and moderate difference (p = 0.034, d = 1.29) in the change in DSI between groups. These results demonstrate that DSI decreases in response to strength training, as expected, due to an increase in isometric mid-thigh pull peak force, with minimal change in dynamic (countermovement jump) peak forc

    School-based self-management interventions for asthma in children and adolescents: a mixed methods systematic review.

    Get PDF
    BACKGROUND: Asthma is a common respiratory condition in children that is characterised by symptoms including wheeze, shortness of breath, chest tightness, and cough. Children with asthma may be able to manage their condition more effectively by improving inhaler technique, and by recognising and responding to symptoms. Schools offer a potentially supportive environment for delivering interventions aimed at improving self-management skills among children. The educational ethos aligns with skill and knowledge acquisition and makes it easier to reach children with asthma who do not regularly engage with primary care. Given the multi-faceted nature of self-management interventions, there is a need to understand the combination of intervention features that are associated with successful delivery of asthma self-management programmes. OBJECTIVES: This review has two primary objectives.• To identify the intervention features that are aligned with successful intervention implementation.• To assess effectiveness of school-based interventions provided to improve asthma self-management among children.We addressed the first objective by performing qualitative comparative analysis (QCA), a synthesis method described in depth later, of process evaluation studies to identify the combination of intervention components and processes that are aligned with successful intervention implementation.We pursued the second objective by undertaking meta-analyses of outcomes reported by outcome evaluation studies. We explored the link between how well an intervention is implemented and its effectiveness by using separate models, as well as by undertaking additional subgroup analyses. SEARCH METHODS: We searched the Cochrane Airways Trials Register for randomised studies. To identify eligible process evaluation studies, we searched MEDLINE, Embase, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO, the Cochrane Database of Systematic Reviews (CDSR), Web of Knowledge, the Database of Promoting Health Effectiveness Reviews (DoPHER), the Database of Abstracts of Reviews of Effects (DARE), the International Biography of Social Science (IBSS), Bibliomap, Health Technology Assessment (HTA), Applied Social Sciences Index and Abstracts (ASSIA), and Sociological Abstracts (SocAbs). We conducted the latest search on 28 August 2017. SELECTION CRITERIA: Participants were school-aged children with asthma who received the intervention in school. Interventions were eligible if their purpose was to help children improve management of their asthma by increasing knowledge, enhancing skills, or changing behaviour. Studies relevant to our first objective could be based on an experimental or quasi-experimental design and could use qualitative or quantitative methods of data collection. For the second objective we included randomised controlled trials (RCTs) where children were allocated individually or in clusters (e.g. classrooms or schools) to self-management interventions or no intervention control. DATA COLLECTION AND ANALYSIS: We used qualitative comparative analysis (QCA) to identify intervention features that lead to successful implementation of asthma self-management interventions. We measured implementation success by reviewing reports of attrition, intervention dosage, and treatment adherence, irrespective of effects of the interventions.To measure the effects of interventions, we combined data from eligible studies for our primary outcomes: admission to hospital, emergency department (ED) visits, absence from school, and days of restricted activity due to asthma symptoms. Secondary outcomes included unplanned visits to healthcare providers, daytime and night-time symptoms, use of reliever therapies, and health-related quality of life as measured by the Asthma Quality of Life Questionnaire (AQLQ). MAIN RESULTS: We included 55 studies in the review. Thirty-three studies in 14,174 children provided information for the QCA, and 33 RCTs in 12,623 children measured the effects of interventions. Eleven studies contributed to both the QCA and the analysis of effectiveness. Most studies were conducted in North America in socially disadvantaged populations. High school students were better represented among studies contributing to the QCA than in studies contributing to effectiveness evaluations, which more commonly included younger elementary and junior high school students. The interventions all attempted to improve knowledge of asthma, its triggers, and stressed the importance of regular practitioner review, although there was variation in how they were delivered.QCA results highlighted the importance of an intervention being theory driven, along with the importance of factors such as parent involvement, child satisfaction, and running the intervention outside the child's own time as drivers of successful implementation.Compared with no intervention, school-based self-management interventions probably reduce mean hospitalisations by an average of about 0.16 admissions per child over 12 months (SMD -0.19, 95% CI -0.35 to -0.04; 1873 participants; 6 studies, moderate certainty evidence). They may reduce the number of children who visit EDs from 7.5% to 5.4% over 12 months (OR 0.70, 95% CI 0.53 to 0.92; 3883 participants; 13 studies, low certainty evidence), and probably reduce unplanned visits to hospitals or primary care from 26% to 21% at 6 to 9 months (OR 0.74, 95% CI 0.60 to 0.90; 3490 participants; 5 studies, moderate certainty evidence). Self-management interventions probably reduce the number of days of restricted activity by just under half a day over a two-week period (MD 0.38 days 95% CI -0.41 to -0.18; 1852 participants; 3 studies, moderate certainty evidence). Effects of interventions on school absence are uncertain due to the variation between the results of the studies (MD 0.4 fewer school days missed per year with self-management (-1.25 to 0.45; 4609 participants; 10 studies, low certainty evidence). Evidence is insufficient to show whether the requirement for reliever medications is affected by these interventions (OR 0.52, 95% CI 0.15 to 1.81; 437 participants; 2 studies; very low-certainty evidence). Self-management interventions probably improve children's asthma-related quality of life by a small amount (MD 0.36 units higher on the Paediatric AQLQ(95% CI 0.06 to 0.64; 2587 participants; 7 studies, moderate certainty evidence). AUTHORS' CONCLUSIONS: School-based asthma self-management interventions probably reduce hospital admission and may slightly reduce ED attendance, although their impact on school attendance could not be measured reliably. They may also reduce the number of days where children experience asthma symptoms, and probably lead to small improvements in asthma-related quality of life. Many of the studies tested the intervention in younger children from socially disadvantaged populations. Interventions that had a theoretical framework, engaged parents and were run outside of children's free time were associated with successful implementation.NIHR CLAHRC North Thames, UK

    Pre-litigation Mediation as a Privacy Policy: Exploring the Interaction of Economics and Privacy

    Get PDF
    Pre-litigation mediation is a perfect example of the economic trade-offs that exist in privacy policy. In pre-litigation mediation, costs and confidentiality work independently. However, there is a precarious balance that exists where, if either confidentiality or cost became less effective the entire mediation process might be damaged

    Pre-litigation Mediation as a Privacy Policy: Exploring the Interaction of Economics and Privacy

    Get PDF
    Pre-litigation mediation is a perfect example of the economic trade-offs that exist in privacy policy. In pre-litigation mediation, costs and confidentiality work independently. However, there is a precarious balance that exists where, if either confidentiality or cost became less effective the entire mediation process might be damaged
    corecore