37 research outputs found
Regulation of cellular proliferation, differentiation and cell death by activated Raf
The protein kinases Raf-1, A-Raf and B-Raf connect receptor stimulation with intracellular signaling pathways and function as a central intermediate in many signaling pathways. Gain-of-function experiments shed light on the pleiotropic biological activities of these enzymes. Expression experiments involving constitutively active Raf revealed the essential functions of Raf in controlling proliferation, differentiation and cell death in a cell-type specific manner
Product and process innovation in manufacturing firms: a 30-year bibliometric analysis
Built upon a thirty-year dataset collected from the Web of Science database, the present research aims to offer a comprehensive overview of papers, authors, streams of research, and the most influential journals that discuss product and process innovation in the manufacturing environment. The dataset is composed of 418 papers from more than 150 journals from the period between 1985 and 2015. Homogeneity analysis by means of alternating least squares (HOMALS) and Social Network Analysis (SNA) are used to accomplish the objectives listed above through the keywords given by authors. Initially, the paper highlights and discusses the similarity between the topics debated by the main journals in this field. Subsequently, a wide-range map of topics is presented highlighting five main areas of interests; namely, performance, patent, small firm, product development, and organization. A SNA is also performed in order to validate the results that emerged from HOMALS. Finally, several insights about future research avenues in the manufacturing field are provided
Apoplastic H2O2 generation mechanisms during extracellular lignin formation in Norway spruce cell culture; effect of H2O2 removal on the phenolic metabolism
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Piracy, Inc.—on the bearing of the firm analogy to pirate organization
Theory of the firm, Organization, Ownership, Pirates, D21, J54, L10, L22, L23, Q13,