Assessment of Potential Abatement provided by Annona Muricata (Prickly Custard Apple Leave) on the Toxic Effects of Aluminium Chloride on Albino Rats

The toxic effects of aluminium Chloride (AlCl3) in albino rats (Rattusnorvegicus) have been studied. The species weighing 250 ± 20g were administered varying concentrations of the LD50 (3630mg/kg body weight), ½ LD50 (1815mg/kg body weight) and ¼ LD50 (907.5 mg/kg body weight) of aluminium Chloride solution orally as drinking water for six weeks after which it was discontinued. The specimens were grouped into three. The first group was administered the various concentrations of (AlCl3) with no  abatement, while the second and third groups were administered the same concentrations of (AlCl3) as the former but were fed respectively with 20% and 50% by weight of aqueous leaf extract of Annona muricata mixed with their feeds for six weeks as abatement. Blood samples were collected for biochemical analysis. The results showed significant increase in the levels of urea, creatine, aspartate aminotransferase (AAT), alkaline phosphatase (ALP), alanine aminotransferase (ALAT), total glyceride, total bilirubin, total cholesterol and glucose levels (P<0.05). However, significant decrease in the levels of these parameters was observed with the application of A. muricata. This reveals the potency of A. muricata leaves to abate the effects of the poison in the kidney and liver of mammals

Impact Of Ikhueniro Dumpsite Leachate On Blood Profile And Blood Film Of Wistar Rats

The challenge of environmental toxicity and the associated unrelenting efforts of man to abate or eradicate its hazards are lifelong efforts. The present study investigated the impact of Ikhueniro dumpsite leachate in Benin City, Nigeria on the hematological blood profile and blood film of Wistar rats. A total of 30 Wistar rats were acclimatized for two weeks and randomly distributed into three groups A to C; group A served as control, while groups B and C were orally administered Leachate only and Leachate + Abatement (Dialium guineenses aqueous leaf extract), respectively, once every 48 hours for 30 days. After the exposure period, the surviving rats in group A and half of the rats in group B and C were examined and sacrificed. The experiment continued with the remaining rats in groups B and C. Group B was given only clean water and C only abatement  following ealier stated schedule, after which the surviving rats were sacrificed and samples collected. Hematological analysis showed that leachate administration in Wistar rats caused an increase in white blood cells (27.65%), platelet count (13.35%), and platelet crit (45.45%); with a decrease in red blood cell count (7.52%), hemoglobin (5.40%) and hematocrit (6.12%) of Wistar rats when compared to the control. Geimsa-stained blood film revealed the presence of polymorphs and basophils in the blood film of rats administered dumpsite leachate. Nevertheless, when leachate administration was stopped in the group of rats where it was previously administered, there was a slight improvement in some blood hematological indices. However, the administration of Dialiumguineense leaf extracts better-improved blood hematological indices. The findings of this study indicate that Ikhueniro dumpsite leachate negatively impacted blood hematological indices in Wistar rats. Dumpsite leachate should be handled and treated carefully to avoid potential health hazards in animals

Preliminary Studies on the Tissues of the Upper Alimentary Canal of the Albino Rat (Rattus norvegicus) Fed with Cadmium Salt

No Abstract Available Discovery and Innovation Vol.16(1&2) 2004: 59-6

The impact of flooding on Nigeria’s sustainable development goals (SDGs)

Nigeria has Africa’s biggest economy and a population of over 200 million people. Nigeria faces numerous challenges as it struggles to achieve the Sustainable Development Goals (SDGs) with flooding being the most serious with wide-reaching impacts. This paper highlights the impact flooding has on Nigeria reaching SDGs and enumerates the specific SDGs most directly impacted. A systematic literature review provides an overview of the relationship between flooding in Nigeria and the SDGs. It highlights the main causes of Nigeria’s flooding problem are man-made and advocates spatial planning as a suitable Flood Risk Management (FRM) strategy for the Nigerian environment. The paper calls for collaborative action by all concerned stakeholders to address the flooding problem and to help move Nigeria closer to meeting the United Nations (UN) 2030 SDGs. Most importantly, the evidence presented in this paper seeks to promote action on a national scale to combat the flooding in Nigeria and help the nation work more effectively toward achieving the SDGs