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Expression of natural killer receptor alleles at different Ly49 loci occurs independently and is regulated by major histocompatibility complex class I molecules.
Ly49 receptor genes are expressed by subsets of natural killer (NK) cells in an overlapping fashion, accounting for the capacity of NK subsets to attack host cells that have selectively downregulated self-major histocompatibility complex (MHC) class I molecules. It was shown previously that most NK cells express only one or the other allele of a given Ly49 gene, while a smaller population expresses both alleles. However, the methods used to detect monoallelic and biallelic cells were nonquantitative. Here, new allele-specific antibodies were used to provide the first quantitative examination of biallelic and monoallelic expression of Ly49A and Ly49G2. The results demonstrate conclusively that most Ly49A(+) and Ly49G2(+) NK cells express the corresponding gene in a monoallelic fashion, with a smaller subset expressing both alleles. Unexpectedly, biallelic Ly49A(+) NK cells were more numerous than predicted by completely independent allelic expression, suggesting some heterogeneity among NK progenitors in the potential to express a given Ly49 gene. The data also show that cells expressing one allele of Ly49G2 may express Ly49A from the same or opposite chromosome with equal likelihood, indicating that the expressed allele is chosen independently for different Ly49 genes. Finally, the data demonstrate that biallelic expression of Ly49A or Ly49G2 occurs least frequently in mice that express ligands for these receptors (H-2(d) mice), and most frequently in class I-deficient mice. Thus, biallelic expression of Ly49 genes is regulated by interactions of NK cell progenitors with MHC class I molecules
Topological susceptibility at zero and finite temperature in the Nambu-Jona-Lasinio model
We consider the three flavor Nambu-Jona-Lasinio model with the 't Hooft
interaction incorporating the U(1)_A anomaly. In order to set the coupling
strength of the 't Hooft term, we employ the topological susceptibility
instead of the eta' meson mass. The value for is taken from lattice
simulations. We also calculate at finite temperature within the model.
Comparing it with the lattice data, we extract information about the behavior
of the U(1)_A anomaly at finite temperature. We conclude that within the
present framework, the effective restoration of the U(1)_A symmetry does not
necessarily take place even at high temperature where the chiral symmetry is
restored.Comment: 9 pages, 14 figures, to be published in Phys.Rev.
Electronic charges and electric potential at LaAlO3/SrTiO3 interfaces studied by core-level photoemission spectroscopy
We studied LaAlO3/SrTiO3 interfaces for varying LaAlO3 thickness by
core-level photoemission spectroscopy. In Ti 2p spectra for conducting "n-type"
interfaces, Ti3+ signals appeared, which were absent for insulating "p-type"
interfaces. The Ti3+ signals increased with LaAlO3 thickness, but started well
below the critical thickness of 4 unit cells for metallic transport. Core-level
shifts with LaAlO3 thickness were much smaller than predicted by the polar
catastrophe model. We attribute these observations to surface
defects/adsorbates providing charges to the interface even below the critical
thickness
Spectroscopy of SrRuO/Ru Junctions in Eutectic
We have investigated the tunnelling properties of the interface between
superconducting Sr2RuO4 and a single Ru inclusion in eutectic. By using a
micro-fabrication technique, we have made Sr2RuO4/Ru junctions on the eutectic
system that consists of Sr2RuO4 and Ru micro-inclusions. Such a eutectic system
exhibits surface superconductivity, called the 3-K phase. A zero bias
conductance peak (ZBCP) was observed in the 3-K phase. We propose to use the
onset of the ZBCP to delineate the phase boundary of a time-reversal symmetry
breaking state.Comment: To be published in Proc of 24th Int. Conf. on Low Temperature Physics
(LT24); 2 page
High Metallicity of the X-Ray Gas up to the Virial Radius of a Binary Cluster of Galaxies: Evidence of Galactic Superwinds at High-Redshift
We present an analysis of a Suzaku observation of the link region between the
galaxy clusters A399 and A401. We obtained the metallicity of the intracluster
medium (ICM) up to the cluster virial radii for the first time. We determine
the metallicity where the virial radii of the two clusters cross each other (~2
Mpc away from their centers) and found that it is comparable to that in their
inner regions (~0.2 Zsun). It is unlikely that the uniformity of metallicity up
to the virial radii is due to mixing caused by a cluster collision. Since the
ram-pressure is too small to strip the interstellar medium of galaxies around
the virial radius of a cluster, the fairly high metallicity that we found there
indicates that the metals in the ICM are not transported from member galaxies
by ram-pressure stripping. Instead, the uniformity suggests that the
proto-cluster region was extensively polluted with metals by extremely powerful
outflows (superwinds) from galaxies before the clusters formed. We also
searched for the oxygen emission from the warm--hot intergalactic medium in
that region and obtained a strict upper limit of the hydrogen density
(nH<4.1x10^-5 cm^-3).Comment: Typo corrected. The published version is available on-line free of
charge by the end of 2008. http://pasj.asj.or.jp/v60/sp1/60s133/60s133.pd
Chemical potential shift induced by double-exchange and polaronic effects in Nd_{1-x}Sr_xMnO_3
We have studied the chemical potential shift as a function of temperature in
NdSrMnO (NSMO) by measurements of core-level photoemission
spectra. For ferromagnetic samples ( and 0.45), we observed an unusually
large upward chemical potential shift with decreasing temperature in the
low-temperature region of the ferromagnetic metallic (FM) phase. This can be
explained by the double-exchange (DE) mechanism if the band is split by
dynamical/local Jahn-Teller effect. The shift was suppressed near the Curie
temperature (), which we attribute to the crossover from the DE to
lattice-polaron regimes.Comment: 5 pages, 6 figure
Earthquake fault rock indicating a coupled lubrication mechanism
International audienceA pseudotachylyte bounded by a carbonate-matrix implosion breccia was found at a fossilized out-of-sequence thrust in the Shimanto accretionary complex, Japan. This occurrence resulted from the following events: first implosion of host rock due to interstitial fluid pressure increase and asymmetric fracturing; second, Ca-Fe-Mg carbonate precipitation; and third, frictional melting. The rock-record suggests that these events took place in a single seismogenic slip event. Resulting from abrupt drop in fluid pressure after implosion, hydro-fracturing and fluid escape, recovered high effective friction promoted melting during fault movement. Coexistence of fluid implosion breccia and pseudotachylyte has never been reported from continental pseudotachylytes, but might be characteristic from hydrous seismogenic faults in subduction zones
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