1,199 research outputs found
Strong Cosmic Censorship and Causality Violation
We investigate the instability of the Cauchy horizon caused by causality
violation in the compact vacuum universe with the topology , which Moncrief and Isenberg considered. We show that if
the occurrence of curvature singularities are restricted to the boundary of
causality violating region, the whole segments of the boundary become curvature
singularities. This implies that the strong cosmic censorship holds in the
spatially compact vacuum space-time in the case of the causality violation.
This also suggests that causality violation cannot occur for a compact
universe.Comment: corrected version, 8 pages, one eps figure is include
Utilizing a biology-driven approach to map the exposome in health and disease:An essential investment to drive the next generation of environmental discovery
BACKGROUND: Recent developments in technologies have offered opportunities to measure the exposome with unprecedented accuracy and scale. However, because most investigations have targeted only a few exposures at a time, it is hypothesized that the majority of the environmental determinants of chronic diseases remain unknown. OBJECTIVES: We describe a functional exposome concept and explain how it can leverage existing bioassays and high-resolution mass spectrometry for exploratory study. We discuss how such an approach can address well-known barriers to interpret exposures and present a vision of next-generation exposomics. DISCUSSION: The exposome is vast. Instead of trying to capture all exposures, we can reduce the complexity by measuring the functional exposome— the totality of the biologically active exposures relevant to disease development—through coupling biochemical receptor-binding assays with affinity purification–mass spectrometry. We claim the idea of capturing exposures with functional biomolecules opens new opportunities to solve critical problems in exposomics, including low-dose detection, unknown annotations, and complex mixtures of exposures. Although novel, biology-based measurement can make use of the existing data processing and bioinformatics pipelines. The functional exposome concept also complements conven-tional targeted and untargeted approaches for understanding exposure-disease relationships. CONCLUSIONS: Although measurement technology has advanced, critical technological, analytical, and inferential barriers impede the detection of many environmental exposures relevant to chronic-disease etiology. Through biology-driven exposomics, it is possible to simultaneously scale up discovery of these causal environmental factors. https://doi.org/10.1289/EHP8327
Precision Primordial He Measurement with CMB Experiments
Big bang nucleosynthesis (BBN) and the cosmic microwave background (CMB) are
two major pillars of cosmology. Standard BBN accurately predicts the primordial
light element abundances (He, D, He and Li), depending on one
parameter, the baryon density. Light element observations are used as a
baryometers. The CMB anisotropies also contain information about the content of
the universe which allows an important consistency check on the Big Bang model.
In addition CMB observations now have sufficient accuracy to not only determine
the total baryon density, but also resolve its principal constituents, H and
He. We present a global analysis of all recent CMB data, with special
emphasis on the concordance with BBN theory and light element observations. We
find and
(fraction of baryon mass as He) using CMB data alone, in agreement with
He abundance observations. With this concordance established we show that
the inclusion of BBN theory priors significantly reduces the volume of
parameter space. In this case, we find
and . We also find that the inclusion of deuterium
abundance observations reduces the and ranges by a factor
of 2. Further light element observations and CMB anisotropy experiments
will refine this concordance and sharpen BBN and the CMB as tools for precision
cosmology.Comment: 7 pages, 3 color figures made minor changes to bring inline with
journal versio
Spin relaxation: From 2D to 1D
In inversion asymmetric semiconductors, spin-orbit interactions give rise to
very effective relaxation mechanisms of the electron spin. Recent work, based
on the dimensionally constrained D'yakonov Perel' mechanism, describes
increasing electron-spin relaxation times for two-dimensional conducting layers
with decreasing channel width. The slow-down of the spin relaxation can be
understood as a precursor of the one-dimensional limit
Spin-dephasing anisotropy for electrons in a diffusive quasi-1D GaAs wire
We present a numerical study of dephasing of electron spin ensembles in a
diffusive quasi-one-dimensional GaAs wire due to the D'yakonov-Perel'
spin-dephasing mechanism. For widths of the wire below the spin precession
length and for equal strength of Rashba and linear Dresselhaus spin-orbit
fields a strong suppression of spin-dephasing is found. This suppression of
spin-dephasing shows a strong dependence on the wire orientation with respect
to the crystal lattice. The relevance for realistic cases is evaluated by
studying how this effect degrades for deviating strength of Rashba and linear
Dresselhaus fields, and with the inclusion of the cubic Dresselhaus term
Discovery of a radio transient in M81
We report the discovery of a radio transient in the spiral galaxy M81. The transient was detected in early 2015 as part of a two-year survey of M81 made up of 12 epochs using the Karl G. Jansky Very Large Array. While undetected on 2014 September 12, the source was first detected on 2015 January 2, from which point it remained visible at an approximately constant luminosity of LR, ν = 1.5 ± 0.1 × 1024 erg s−1 Hz−1 at the observing frequency of 6 GHz for at least 2 months. Assuming this is a synchrotron event with a rise-time between 2.6 and 112 d, the peak luminosity (at equipartition) corresponds to a minimum energy of 1044 ≾ Emin ≾ 1046 erg and jet power of Pmin ∼ 1039 erg s−1, which are higher than most known X-ray binaries. Given its longevity, lack of short-term radio variability, and the absence of any multiwavelength counterpart (X-ray luminosity Lx ≾ 1036 erg s−1), it does not behave like known Galactic or extragalactic X-ray binaries. The M81 transient radio properties more closely resemble the unidentified radio transient 43.78+59.3 discovered in M82, which has been suggested to be a radio nebula associated with an accreting source similar to SS 433. One possibility is that both the new M81 transient and the M82 transient may be the birth of a short-lived radio bubble associated with a discrete accretion event similar to those observed from the ULX Holmberg II X-1. However, it is not possible to rule out other identifications including long-term supernova shockwave interactions with the surrounding medium from a faint supernova or a background active galaxy
Determination of the Deep Inelastic Contribution to the Generalised Gerasimov-Drell-Hearn Integral for the Proton and Neutron
The virtual photon absorption cross section differences [sigma_1/2-sigma_3/2]
for the proton and neutron have been determined from measurements of polarised
cross section asymmetries in deep inelastic scattering of 27.5 GeV
longitudinally polarised positrons from polarised 1H and 3He internal gas
targets. The data were collected in the region above the nucleon resonances in
the kinematic range nu < 23.5 GeV and 0.8 GeV**2 < Q**2 < 12 GeV**2. For the
proton the contribution to the generalised Gerasimov-Drell-Hearn integral was
found to be substantial and must be included for an accurate determination of
the full integral. Furthermore the data are consistent with a QCD
next-to-leading order fit based on previous deep inelastic scattering data.
Therefore higher twist effects do not appear significant.Comment: 6 pages, 3 figures, 1 table, revte
Observation of a Coherence Length Effect in Exclusive Rho^0 Electroproduction
Exclusive incoherent electroproduction of the rho^0(770) meson from 1H, 2H,
3He, and 14N targets has been studied by the HERMES experiment at squared
four-momentum transfer Q**2>0.4 GeV**2 and positron energy loss nu from 9 to 20
GeV. The ratio of the 14N to 1H cross sections per nucleon, known as the
nuclear transparency, was found to decrease with increasing coherence length of
quark-antiquark fluctuations of the virtual photon. The data provide clear
evidence of the interaction of the quark- antiquark fluctuations with the
nuclear medium.Comment: RevTeX, 5 pages, 3 figure
Measurement of the Neutron Spin Structure Function with a Polarized ^3He Target
Results are reported from the HERMES experiment at HERA on a measurement of
the neutron spin structure function in deep inelastic scattering
using 27.5 GeV longitudinally polarized positrons incident on a polarized
He internal gas target. The data cover the kinematic range
and . The integral evaluated at a fixed of is . Assuming Regge behavior at low , the first
moment is .Comment: 4 pages TEX, text available at
http://www.krl.caltech.edu/preprints/OAP.htm
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