17 research outputs found
Cellular Adhesion to Carbon Nanotubes-anchored Oligonucleotide: Electro-chemical Detection
In the study a new biosensor contained an oligonucleotide-carbon nanotubes-stearic acid monocrystalline
clusters in its sensitive coating has been developed. The electrochemical characteristics of sensors with
different coatings distinguishing by content of oligonucleotide and cerium ions have been measured. It was
found that the presence of Ce in the coating leads to decrease of sensor capacity changes at measurements
in mediums of different content. The oligonucleotides anchored in sensor coating attenuate cell nonantisense
adhesion to sensor surface.
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The development of the School of Thought in Physiology of Heart Aging in Kazan
The study of heart aging physiology at Kazan Pedagogical University was for many years headed by Professor Farit Gabdulkhakovich Sitdikov, Doctor of Biology, Meritorious Scientist of the Russian Federation and the Republic of Tatarstan. The focus of his research interests was membranous and cellular mechanisms of heart regulation in ontogeny and adaptation of children and adolescents to studying and physical activities. T.L. Zefirov, the successor of F.G. Sitdikov, continued and promoted these investigations within the walls of the Institute of Fundamental Medicine and Biology of Kazan Federal University. The experiments are performed here with the use of unique physiological equipment that helps to spot the age-related features of heart functioning at the organ, tissue, and cellular levels, as well as to find out how various medications affect the heart. The most important results have been published in the leading Russian and foreign journals
Quinone regulation of mitochondria functional activity
Comparative study of quinones influence on mitochondrial respiration activity and membrane potential changes have been carried out