OPTIMIZATION OF INTERNAL QUALITY’S CONTROL OF MEDICAL HELP IN ROSTOV STATE MEDICAL UNIVERSITY

The article presents the results of analysis of the four-level’s system of internal quality’s control in Rostov State Medical University. There is a unified electronic database of quality’s control in the University’s clinic. Analysis of the results of quality’s control allows us to made the elimination and prevention of irregularities. During the reporting periods the electronic system calculates a mark of the medical help for each patient, a mark of the work of each doctor, a mark of the work of all departments. The marks of the electronic system seems to us as possibility to improve measures of personal responsibility of staff and to achieve collective results of work

PECULIARITIES OF OCCUPATIONAL ILLNESS FORMATION IN ROSTOV REGION

The data base on occupational illness in Rostov region in 2002—2011 has been formed. Branch and occupational structure and. dynamics of relative indices of occupational illness with the economics branch consideration have been analysed. The tendency of reducing occupational illness indices in Rostov region has been revealed, it being caused by incomplete revealing the patients with occupational illness. Coal mining industry, in which the high level of occupational illness is caused by the extremely unfavourable conditions of labor, is an exception. It is necessary to increase the efficiency of periodical medical examinations, especially for agricultural workers, in order to reveal the real level of occupational illness

THE PROBLEMS OF OCCUPATIONAL PATHOLOGY AND REHABILITATION TREATMENT OF WORKERS WORKING AT HARMFUL CONDITIONS OF LABOR

It is necessary to create the low of RF (the Decree of the government of RF) which will clearly define the order of organization and carrying out medical examinations of workers of harmful occupations and. their financing. For the organizations of prevention of occupational diseases and. medical rehabilitation of patients with occupational diseases during working out the order of financial security of preventive measures for reducing occupational diseases. It is necessary: to include into the list of preventive measures profound medical examinations of workers in the centres of occupational pathology, rehabilitation treatment of workers from the group of "risk" and patients with initial displays of occupational diseases in the centres of occupational pathology (rehabilitation centres); to insert the changes into the Federal Law no 125-03, supplementing the list of kinds of financial security for insurance of medical rehabilitation of the insured patients in the centres of occupational pathology (the centres of rehabilitation); to include into the Federal programme of compulsory medical insurance occupational pathology help

EXPERIENCE OF ORGANIZATION OF PERIODICAL MEDICAL EXAMINATIONS WITH USING MOVABLE CLINICAL DIAGNOSTIC LABORATORIES

The expediency of introducing the system of movable clinical diagnostic laboratories for well-timed medical service of high quality for workers with high level of occupational risk has been grounded in this work, the efficiency of their activity in carrying out obligatory medical examinations of workers of harmful occupations in the period of making the home system of obligatory insurance against accidents in industry and occupational disease has been proved

INFLUENCE OF ARTIFICIAL HUMAN ADAPTATION TO INTERMITTENT NORMOBARIC ANOXIA ON THE OPTIONS OF ERYTHROCYTES OF CIRCULATING BLOOD

Purpose: to estimate changes and dynamics of the options of circulating blood erythrocytes in artificial human adaptation to intermittent normobaric hypoxia.Materials and methods: Sixteen healthy male volunteers aged 20-24 years were underwent to course of artificial adaptation to intermittent normobaric hypoxia (AAINH): 1,5 h daily for 30 days in the gas atmosphere with an oxygen content of 13.5%. Venous blood samples were collected before exposure (day 0), day after exposure, then after 3 and 6 months.Results: adaptive changes of red blood cells after the course of AAINH were registered in all cases. Moderate reduction of the number of circulating erythrocytes, hematocrit and average erythrocyte volume were noticed. At the same time such parameter as hemoglobin concentration and it’s content in red blood cell was significantly higher than an average one. The long-term follow up demonstrated that the registered trends were continued.Summary: use of AAINH accompanied with increasing oxygen capacity of circulating blood (due to the synthesis of improved oxygen capasity of red cells), while «determination» to prevent the deterioration of its rheological properties

An early history of T cell-mediated cytotoxicity.

After 60 years of intense fundamental research into T cell-mediated cytotoxicity, we have gained a detailed knowledge of the cells involved, specific recognition mechanisms and post-recognition perforin-granzyme-based and FAS-based molecular mechanisms. What could not be anticipated at the outset was how discovery of the mechanisms regulating the activation and function of cytotoxic T cells would lead to new developments in cancer immunotherapy. Given the profound recent interest in therapeutic manipulation of cytotoxic T cell responses, it is an opportune time to look back on the early history of the field. This Timeline describes how the early findings occurred and eventually led to current therapeutic applications

CLINICO-ECONOMICAL ANALYSIS OF THE TREATMENT EFFICACY IN PATIENTS WITH ARTERIAL HYPERTENSION OF 1-2 DEGREES

Aim. Clinico-economical analysis of arterial hypertension (HT) treatmentMaterial and methods. 78 patients with HT were involved into the study. Patients were spitted into two groups depending on HT degree. The first group – 38 patients with HT 1 degree. The second one – 40 patients with HT 2 degree. Patients of group 1 had initial antihypertensive therapy with angiotensinconverting enzyme inhibitors. If target level of blood pressure (BP) had not been reached, therapy was changed on fixed combination of lisinopril and hydrochlorothiazide. Patients of group 2 had initial combined antihypertensive therapy with lisinopril and hydrochlorothiazide. If it was needed amlodipine maleat was added. Clinico-economical analysis was performed according to “cost-efficacy” approach at the end of 3 month therapy.Results. About 50% of hypertensive patients do not follow physician recommendations in out-patient practice. They decrease a dose of medicine or stop therapy themselves. More than 6% of them perform self-treatment.Conclusion. Analysis showed that therapy of patients with HT of 1 degree is economically more profitable regarding target BP achievement. It is more reasonable to start antihypertensive therapy with fixed low dose combination and add calcium antagonists if it is needed in patients with HT of 2 degree.</p