Stochastic integration based on simple, symmetric random walks

A new approach to stochastic integration is described, which is based on an a.s. pathwise approximation of the integrator by simple, symmetric random walks. Hopefully, this method is didactically more advantageous, more transparent, and technically less demanding than other existing ones. In a large part of the theory one has a.s. uniform convergence on compacts. In particular, it gives a.s. convergence for the stochastic integral of a finite variation function of the integrator, which is not c\`adl\`ag in general.Comment: 16 pages, some typos correcte

Higher-order numerical methods for stochastic simulation of\ud chemical reaction systems

In this paper, using the framework of extrapolation, we present an approach for obtaining higher-order -leap methods for the Monte Carlo simulation of stochastic chemical kinetics. Specifically, Richardson extrapolation is applied to the expectations of functionals obtained by a fixed-step -leap algorithm. We prove that this procedure gives rise to second-order approximations for the first two moments obtained by the chemical master equation for zeroth- and first-order chemical systems. Numerical simulations verify that this is also the case for higher-order chemical systems of biological importance. This approach, as in the case of ordinary and stochastic differential equations, can be repeated to obtain even higher-order approximations. We illustrate the results of a second extrapolation on two systems. The biggest barrier for observing higher-order convergence is the Monte Carlo error; we discuss different strategies for reducing it

Description of two new actinosporean types from a brook of Fuji Mountain, Honshu, and from Chitose River, Hokkaido, Japan

Actinospore infection of oligochaetes living in the mud of 3 freshwater biotopes in Japan was studied. Using the cell-well plate method, a new aurantiactinomyxon type was found in 0.77 % of the examined Tubifex tubifex oligochaete specimens from a brook near Yamanashi Prefectural Fisheries Experimental Station on Fuji Mountain. In 0.14 % of Lumbriculus variagetus collected from Chitose River, near Chitose Salmon Hatchery, a new siedleckiella type was found, while at the same time 8.1 % of the Lumbriculus spp. oligochaetes released triactinomyxons of Myxobolus arcticus. Of the examined Rhyacodrilus komarovi oligochaetes collected from the Mena River system, Hokkaido, 0.2, 0.6, 0.5 and 0.8% were infected with echinactinomyxon, neoactinomyxum and 2 types of triactinomyxon spores, respectively, and described in our previous paper. The oligochaetes released actinospores for several weeks. Actinospore infection showed high intensity in positive oligochaetes in the case of all the actinosporean types. Two of the actinospore types (aurantiactinomyxon and siedleckiella) presented here have not been previously described

Fiscal policy in the EU in the crisis: a model-based approach

This paper uses a multi region DSGE model with collateral constrained households and residential investment to examine the effectiveness of fiscal policy stimulus measures in a credit crisis. The paper explores alternative scenarios which differ by the type of budgetary measure, its length, the degree of monetary accommodation and the level of international coordination. In particular we provide estimates for New EU Member States where we take into account two aspects. First, debt denomination in foreign currency and second, higher nominal interest rates, which makes it less likely that the Central Bank is restricted by the zero bound and will consequently not accommodate a fiscal stimulus. We also compare our results to other recent results obtained in the literature on fiscal policy which generally do not consider credit constrained households.Fiscal Policy, Monetary Policy, Fiscal Multiplier, Collateral Constraint, DSGE modelling

Polymorphism in the serotonin receptor 2a (HTR2A) gene as possible predisposal factor for aggressive traits

Aggressive manifestations and their consequences are a major issue of mankind, highlighting the need for understanding the contributory factors. Still, aggression-related genetic analyses have so far mainly been conducted on small population subsets such as individuals suffering from a certain psychiatric disorder or a narrow-range age cohort, but no data on the general population is yet available. In the present study, our aim was to identify polymorphisms in genes affecting neurobiological processes that might explain some of the inter-individual variation between aggression levels in the non-clinical Caucasian adult population. 55 single nucleotide polymorphisms (SNP) were simultaneously determined in 887 subjects who also filled out the self-report Buss-Perry Aggression Questionnaire (BPAQ). Single marker association analyses between genotypes and aggression scores indicated a significant role of rs7322347 located in the HTR2A gene encoding serotonin receptor 2a following Bonferroni correction for multiple testing (p = 0.0007) both for males and females. Taking the four BPAQ subscales individually, scores for Hostility, Anger and Physical Aggression showed significant association with rs7322347 T allele in themselves, while no association was found with Verbal Aggression. Of the subscales, relationship with rs7322347 was strongest in the case of Hostility, where statistical significance virtually equaled that observed with the whole BPAQ. In conclusion, this is the first study to our knowledge analyzing SNPs in a wide variety of genes in terms of aggression in a large sample-size non-clinical adult population, also describing a novel candidate polymorphism as predisposal to aggressive traits

Discovery of the spectroscopic binary nature of three bright southern Cepheids

We present an analysis of spectroscopic radial velocity and photometric data of three bright Galactic Cepheids: LR Trianguli Australis (LR TrA), RZ Velorum (RZ Vel), and BG Velorum (BG Vel). Based on new radial velocity data, these Cepheids have been found to be members of spectroscopic binary systems. The ratio of the peak-to-peak radial velocity amplitude to photometric amplitude indicates the presence of a companion for LR TrA and BG Vel. IUE spectra indicate that the companions of RZ Vel and BG Vel cannot be hot stars. The analysis of all available photometric data revealed that the pulsation period of RZ Vel and BG Vel varies monotonically, due to stellar evolution. Moreover, the longest period Cepheid in this sample, RZ Vel, shows period fluctuations superimposed on the monotonic period increase. The light-time effect interpretation of the observed pattern needs long-term photometric monitoring of this Cepheid. The pulsation period of LR TrA has remained constant since the discovery of its brightness variation. Using statistical data, it is also shown that a large number of spectroscopic binaries still remain to be discovered among bright classical Cepheids.Comment: 9 pages, 14 figure

Fiscal policy in the EU in the crisis: A model-based approach

This paper uses a multi region DSGE model with collateral constrained households and residential investment to examine the effectiveness of fiscal policy stimulus measures in a credit crisis. The paper explores alternative scenarios which differ by the type of budgetary measure, its length, the degree of monetary accommodation and the level of international coordination. In particular we provide estimates for New EU Member States where we take into account two aspects. First, debt denomination in foreign currency and second, higher nominal interest rates, which makes it less likely that the Central Bank is restricted by the zero bound and will consequently not accommodate a fiscal stimulus. We also compare our results to other recent results obtained in the literature on fiscal policy which generally do not consider credit constrained households