The effectiveness of cognitive processing therapy and prolonged exposure in the Department of Veterans Affairs.

Multiple randomized clinical trials have shown that cognitive processing therapy (CPT) and prolonged exposure (PE) are evidence-based treatments for posttraumatic stress disorder (PTSD). However, additional research should verify the effectiveness of CPT and PE in conditions more reflective of clinical practice. The present study evaluated the effectiveness of CPT and PE at reducing veterans' self-reported PTSD symptoms as measured by total scores on the PTSD Checklist (PCL). This study involved a retrospective review of 2,030 charts. 750 veterans from 10 U.S. states who received CPT or PE in individual psychotherapy from the Veterans Health Administration were included in the study (N participants in CPT = 376; N participants in PE = 374). The study used multilevel modeling to evaluate the absolute and relative effectiveness of both treatments and to determine the relationship between patient-level factors and total PCL scores during treatment. Results showed that both CPT and PE were equally effective at reducing total PCL scores, but that the effectiveness of both therapies was reduced when compared to results obtained in randomized clinical trials. Patients who completed therapy reported significantly larger reductions on the PCL than patients who did not complete therapy. On average, patients who did not complete a full course of therapy reported little to no improvement on the PCL. Encouragingly, as a group these patients did not report an increase in the severity of their total PCL scores prior to dropping out from therapy. Patients who reported more severe total PCL scores at baseline experienced significantly larger reductions in PCL scores during therapy, but veterans at all levels of initial PTSD symptom severity benefited from treatment. Older veterans and Hispanic veterans had higher total PCL scores at baseline. However, veterans across all ages and three racial/ethnic groups (Caucasian, African American, Hispanic) experienced equivalent rates of symptom reduction. Therapist effects were small, but statistically significant. The study discusses the significance of these findings in light of prior research on trauma-focused therapy, future directions for research, and implications for practice

Multi-academy Trusts: do they make a difference to pupil outcomes?

This report is published as a supplement to the main project research report, Hierarchy, Markets and Networks: Analysing the ‘self-improving school-led system’ agenda in England and the implications for schools. The main project report analyses how schools in England have interpreted and begun to respond to the government’s ‘self-improving school-led system’ (SISS) policy agenda, an overarching narrative for schools policy since 2010 that encompasses an ensemble of reforms including academies, multi-academy trusts (MATs) and teaching school alliances (TSAs). The statistical analysis of MAT impact on pupil attainment and progress set out in this supplementary report is the first published analysis to compare schools in MATs over a three-year period with standalone academies and maintained schools with similar characteristics and levels of prior pupil attainment. The analysis set out here uses 2013–15 attainment data and 2016 data on the composition of MATs. Our finding in this paper that there is no positive impact from MAT status overall is largely consistent with other recent studies (Hutchings and Francis, 2017; Andrews, 2019). Where this report provides significant new evidence is in terms of MAT size, as we show that pupils in small and mid-sized MATs tend to perform better, on average, than their peers in comparable maintained schools in both phases and, in the primary phase, than comparable standalone academies. Conversely, secondary school pupils in larger MATs (with 16+ schools) tend to do worse compared to those in both standalone academies and maintained schools. These findings suggest that the economic drive for MAT growth promoted in contemporary policy may well be in tension with an educational argument for smaller groupings of schools

A High-Resolution Sensor Network for Monitoring Glacier Dynamics

This paper provides an overview of a wide area wireless sensor network that was deployed on the calving front of the Helheim Glacier in Greenland during the summer of 2013. The purpose of the network was to measure the flow rate of the glacier using accurate satellite positioning data. The challenge in this extreme environment was to collect data in real time at the calving edge of the glacier. This was achieved using a solar powered 2.4-GHz Zigbee wireless sensor network operated in a novel hybrid cellular/mesh access architecture consisting of ice nodes communicating with base stations placed on the rock adjacent to the glacier. This highly challenging transmission environment created substantial signal outage conditions, which were successfully mitigated by a radio network diversity scheme. The network development and measurement campaign were highly successful yielding significant results on glacial dynamics associated with climate change

Modelling environmental influences on calving at Helheim Glacier in eastern Greenland

Calving is an important mass-loss process for many glaciers worldwide, and has been assumed to respond to a variety of environmental influences. We present a grounded, flowline tidewater glacier model using a physically-based calving mechanism, applied to Helheim Glacier, eastern Greenland. By qualitatively examining both modelled size and frequency of calving events, and the subsequent dynamic response, the model is found to realistically reproduce key aspects of observed calving behaviour. Experiments explore four environmental variables which have been suggested to affect calving rates: water depth in crevasses, basal water pressure, undercutting of the calving face by submarine melt and backstress from ice mélange. Of the four variables, only crevasse water depth and basal water pressure were found to have a significant effect on terminus behaviour when applied at a realistic magnitude. These results are in contrast to previous modelling studies, which have suggested that ocean temperatures could strongly influence the calving front. The results raise the possibility that Greenland outlet glaciers could respond to the recent trend of increased surface melt observed in Greenland more strongly than previously thought, as surface ablation can strongly affect water depth in crevasses and water pressure at the glacier bed

Epitaxial growth of high quality ZnS films on sapphire and silicon by pulsed laser deposition

We report for the first time, epitaxial growth of high-quality ZnS films on sapphire and silicon substrates, using pulsed laser deposition. X-ray diffraction results show that at all growth temperatures from 200°C to 680°C, epitaxial wurtzite (002) ZnS films have been successfully grown on (1012) sapphire and (001) silicon substrates. X-ray diffraction data yield full width at half maximum 2theta values of 0.13° for as-grown samples, compared with 28 values or 0.09° and 0.08° for the bare sapphire and silicon substrates respectively

X-ray scattering study of two length scales in the critical fluctuations of CuGeO3

The critical fluctuations of CuGeO$_3$ have been measured by synchrotron x-ray scattering, and two length scales are clearly observed. The ratio between the two length scales is found to be significantly different along the $a$ axis, with the $a$ axis along the surface normal direction. We believe that such a directional preference is a clear sign that surface random strains, especially those caused by dislocations, are the origin of the long length scale fluctuations.Comment: 5 pages, 4 figures, submitted to PR

Reverse glacier motion during iceberg calving and the cause of glacial earthquakes

Nearly half of Greenland’s mass loss occurs through iceberg calving, but the physical mechanisms operating during calving are poorly known and in situ observations are sparse. We show that calving at Greenland’s Helheim Glacier causes a minutes-long reversal of the glacier’s horizontal flow and a downward deflection of its terminus. The reverse motion results from the horizontal force caused by iceberg capsize and acceleration away from the glacier front. The downward motion results from a hydrodynamic pressure drop behind the capsizing berg, which also causes an upward force on the solid Earth. These forces are the source of glacial earthquakes, globally detectable seismic events whose proper interpretation will allow remote sensing of calving processes occurring at increasing numbers of outlet glaciers in Greenland and Antarctica

Measurements of Deuteron Photodisintegration up to 4.0 GeV

The first measurements of the differential cross section for the d(gamma,p)n reaction up to 4.0 GeV were performed at Continuous Electron Beam Accelerator Facility (CEBAF) at Jefferson Lab. We report the cross sections at the proton center-of-mass angles of 36, 52, 69 and 89 degrees. These results are in reasonable agreement with previous measurements at lower energy. The 89 and 69 degree data show constituent-counting-rule behavior up to 4.0 GeV photon energy. The 36 and 52 degree data disagree with the counting rule behavior. The quantum chromodynamics (QCD) model of nuclear reactions involving reduced amplitudes disagrees with the present data.Comment: 5 pages (REVTeX), 1 figure (postscript

Neuroimage

The thalamus is a central integration structure in the brain, receiving and distributing information among the cerebral cortex, subcortical structures, and the peripheral nervous system. Prior studies clearly show that the thalamus atrophies in cognitively unimpaired aging. However, the thalamus is comprised of multiple nuclei involved in a wide range of functions, and the age-related atrophy of individual thalamic nuclei remains unknown. Using a recently developed automated method of identifying thalamic nuclei (3T or 7T MRI with white-matter-nulled MPRAGE contrast and THOMAS segmentation) and a cross-sectional design, we evaluated the age-related atrophy rate for 10 thalamic nuclei (AV, CM, VA, VLA, VLP, VPL, pulvinar, LGN, MGN, MD) and an epithalamic nucleus (habenula). We also used T1-weighted images with the FreeSurfer SAMSEG segmentation method to identify and measure age-related atrophy for 11 extra-thalamic structures (cerebral cortex, cerebral white matter, cerebellar cortex, cerebellar white matter, amygdala, hippocampus, caudate, putamen, nucleus accumbens, pallidum, and lateral ventricle). In 198 cognitively unimpaired participants with ages spanning 20–88 years, we found that the whole thalamus atrophied at a rate of 0.45% per year, and that thalamic nuclei had widely varying age-related atrophy rates, ranging from 0.06% to 1.18% per year. A functional grouping analysis revealed that the thalamic nuclei involved in cognitive (AV, MD; 0.53% atrophy per year), visual (LGN, pulvinar; 0.62% atrophy per year), and auditory/vestibular (MGN; 0.64% atrophy per year) functions atrophied at significantly higher rates than those involved in motor (VA, VLA, VLP, and CM; 0.37% atrophy per year) and somatosensory (VPL; 0.32% atrophy per year) functions. A proximity-to-CSF analysis showed that the group of thalamic nuclei situated immediately adjacent to CSF atrophied at a significantly greater atrophy rate (0.59% atrophy per year) than that of the group of nuclei located farther from CSF (0.36% atrophy per year), supporting a growing hypothesis that CSF-mediated factors contribute to neurodegeneration. We did not find any significant hemispheric differences in these rates of change for thalamic nuclei. Only the CM thalamic nucleus showed a sex-specific difference in atrophy rates, atrophying at a greater rate in male versus female participants. Roughly half of the thalamic nuclei showed greater atrophy than all extra-thalamic structures examined (0% to 0.54% per year). These results show the value of white-matter-nulled MPRAGE imaging and THOMAS segmentation for measuring distinct thalamic nuclei and for characterizing the high and heterogeneous atrophy rates of the thalamus and its nuclei across the adult lifespan. Collectively, these methods and results advance our understanding of the role of thalamic substructures in neurocognitive and disease-related changes that occur with aging. © 2022Initiative d'excellence de l'Université de Bordeau

Measurement of the Induced Proton Polarization P_n in the 12C(e,e'\vec{p}) Reaction

The first measurements of the induced proton polarization, P_n, for the 12C (e,e'\vec{p}) reaction are reported. The experiment was performed at quasifree kinematics for energy and momentum transfer (\omega,q) \approx (294 MeV, 756 MeV/c) and sampled a recoil momentum range of 0-250 MeV/c. The induced polarization arises from final-state interactions and for these kinematics is dominated by the real part of the spin-orbit optical potential. The distorted-wave impulse approximation provides good agreement with data for the 1p_{3/2} shell. The data for the continuum suggest that both the 1s_{1/2} shell and underlying l > 1 configurations contribute.Comment: 5 pages LaTeX, 2 postscript figures, accepted by Physical Reveiw Letter