7,583 research outputs found
Control of beam propagation in optically written waveguides beyond the paraxial approximation
Beam propagation beyond the paraxial approximation is studied in an optically
written waveguide structure. The waveguide structure that leads to
diffractionless light propagation, is imprinted on a medium consisting of a
five-level atomic vapor driven by an incoherent pump and two coherent spatially
dependent control and plane-wave fields. We first study propagation in a single
optically written waveguide, and find that the paraxial approximation does not
provide an accurate description of the probe propagation. We then employ
coherent control fields such that two parallel and one tilted Gaussian beams
produce a branched waveguide structure. The tilted beam allows selective
steering of the probe beam into different branches of the waveguide structure.
The transmission of the probe beam for a particular branch can be improved by
changing the width of the titled Gaussian control beam as well as the intensity
of the spatially dependent incoherent pump field.Comment: 10 pages, 9 figure
The role of the immune system in brain metastasis
Metastatic brain tumors are the most common brain tumors in adults. With numerous successful advancements in systemic treatment of most common cancer types, brain metastasis is becoming increasingly important in the overall prognosis of cancer patients. Brain metastasis of peripheral tumor is the result of complex interplay of primary tumor, immune system and central nervous system microenvironment. Once formed, brain metastases hide behind the blood brain barrier and become inaccessible to chemotherapies that are otherwise successful in targeting systemic cancer. The approval of immune checkpoint inhibitors for several common cancers such as advanced melanoma and lung cancers brings with it the opportunity and obligation to further understand the mechanisms of immunosuppression by tumors that spread to the brain as well as the interaction between the brain environment and tumor microenvironment. In this review paper we define the central role of the immune system in the development of brain metastases. We performed a comprehensive review of the literature to outline the molecular mechanisms of immunosuppression used by tumors and how the immune system interacts with the central nervous system to facilitate brain metastasis. In particular we discuss the tumor-type-specific mechanisms of metastasis of cancers that preferentially metastasize to the brain as well as the therapies that effectively modulate the immune response, such as immune checkpoint inhibitors and vaccines
Born-Infeld black holes coupled to a massive scalar field
Born-Infeld black holes in the Scalar-Tensor Theories of Gravity, in the case
of massless scalar field, have been recently obtained. The aim of the current
paper is to study the effect from the inclusion of a potential for the scalar
field in the theory, through a combination of analytical techniques and
numerical methods. The black holes coupled to a massive scalar field have
richer causal structure in comparison to the massless scalar field case. In the
latter case, the black holes may have a second, inner horizon. The presence of
potential for the scalar field allows the existence of extremal black holes for
certain values of the mass of the scalar field and the magnetic (electric)
charge of the black hole. The linear stability against spherically symmetric
perturbations is studied. Arguments in favor of the general stability of the
solutions coming from the application of the "turning point" method are also
presented.Comment: 26 pages, 16 figure
Competition between Electromagnetically Induced Transparency and Raman Processes
We present a theoretical formulation of competition among electromagnetically
induced transparency (EIT) and Raman processes. The latter become important
when the medium can no longer be considered to be dilute. Unlike the standard
formulation of EIT, we consider all fields applied and generated as interacting
with both the transitions of the scheme. We solve Maxwell equations
for the net generated field using a fast-Fourier-transform technique and obtain
predictions for the probe, control and Raman fields. We show how the intensity
of the probe field is depleted at higher atomic number densities due to the
build up of multiple Raman fields.Comment: 3.5 pages, 7 figure
Ultraslow light in inhomogeneously broadened media
We calculate the characteristics of ultraslow light in an inhomogeneously
broadened medium. We present analytical and numerical results for the group
delay as a function of power of the propagating pulse. We apply these results
to explain the recently reported saturation behavior [Baldit {\it et al.}, \prl
{\bf 95}, 143601 (2005)] of ultraslow light in rare earth ion doped crystal.Comment: 4 pages, 5 figure
Optical cloning of arbitrary images beyond the diffraction limits
Cloning of arbitrary images encoded onto the spatial profile of a laser beam
onto that of a second beam is theoretically investigated. The two fields couple
to an atomic lambda system in a coherent population trapping configuration. In
particular, the case in which the probe and control fields are of comparable
strength is considered. By considering more and more complex structures, we
eventually find that our method is suitable to clone arbitrary images, which we
demonstrated by a full numerical simulation of the propagation dynamics of both
applied fields in the atomic medium, with the three letters "CPT" encoded on
the initial control field profile. We find that the cloned structures have
feature sizes reduced by about a factor of 2 compared to the initial images,
consistent with a recent related experiment.Comment: 9 pages, 8 figure
Coupled solitons in rare-earth doped two-mode fiber
We present first ever analytical solutions for shape-preserving pulses in a Kerr nonlinear two-mode fiber doped with 3-level Λatoms. The two modes are near-resonant with the two transitions of the atomic system. We show the existence of quasi-stable coupled bright-dark pairs if the group velocity dispersion has opposite signs at the two mode frequencies. We demonstrate the remarkable possibility allowed by the fiber dispersion for the existence of a new class of solutions for unequal coupling constants for the two modes. We present the conditions for existence and the analytical form of these solutions in presence of atomic detuning. We confirm numerically the analytical solutions for the spatio-temporal evolution of coupled solitary waves
Phases of 4D Scalar-tensor black holes coupled to Born-Infeld nonlinear electrodynamics
Recent results show that when non-linear electrodynamics is considered the
no-scalar-hair theorems in the scalar-tensor theories (STT) of gravity, which
are valid for the cases of neutral black holes and charged black holes in the
Maxwell electrodynamics, can be circumvented. What is even more, in the present
work, we find new non-unique, numerical solutions describing charged black
holes coupled to non-linear electrodynamics in a special class of scalar-tensor
theories. One of the phases has a trivial scalar field and coincides with the
corresponding solution in General Relativity. The other four phases that we
find are characterized by the value of the scalar field charge. The causal
structure and some aspects of the stability of the solutions have also been
studied. For the scalar-tensor theories considered, the black holes have a
single, non-degenerate horizon, i.e., their causal structure resembles that of
the Schwarzschild black hole. The thermodynamic analysis of the stability of
the solutions indicates that a phase transition may occur.Comment: 18 pages, 8 figures, new phases, figures, clarifying remarks and
acknowledgements adde
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