Cost effective power amplifiers for pulsed NMR sensors

Sensors that measure magnetic resonance relaxation times are increasingly finding applications in areas such as food and drink authenticity and waste water treatment control. Modern permanent magnets are used to provide the static magnetic field in many commercial instruments and advances in electronics, such as field programmable gate arrays, have provided lower cost console electronics for generating and detecting the pulse sequence. One area that still remains prohibitively expensive for many sensor applications of pulsed NMR is the requirement for a high frequency power amplifier. With many permanent magnet sensors providing a magnetic field in the 0.25T to 0.5T range, a power amplifier that operates in the 10MHz to 20MHz rage is required. In this work we demonstrate that some low cost commercial amplifiers can be used, with minor modification, to operate as pulsed NMR power amplifiers. We demonstrate two amplifier systems, one medium power that can be constructed for less than Euro 100 and a second much high power system that produces comparable results to commercial pulse amplifiers that are an order of magnitude more expensive. Data is presented using both the commercial NMR MOUSE and a permanent magnet system used for monitoring the clog state of constructed wetlands

Longitudinal RNA-Seq analysis of acute and chronic neurogenic skeletal muscle atrophy.

Skeletal muscle is a highly adaptable tissue capable of changes in size, contractility, and metabolism according to functional demands. Atrophy is a decline in mass and strength caused by pathologic loss of myofibrillar proteins, and can result from disuse, aging, or denervation caused by injury or peripheral nerve disorders. We provide a high-quality longitudinal RNA-Seq dataset of skeletal muscle from a cohort of adult C57BL/6J male mice subjected to tibial nerve denervation for 0 (baseline), 1, 3, 7, 14, 30, or 90 days. Using an unbiased genomics approach to identify gene expression changes across the entire longitudinal course of muscle atrophy affords the opportunity to (1) establish acute responses to denervation, (2) detect pathways that mediate rapid loss of muscle mass within the first week after denervation, and (3) capture the molecular phenotype of chronically atrophied muscle at a stage when it is largely resistant to recovery

A Low Cost Magnetic Resonance Relaxometry Sensor

Magnetic resonance relaxometry, conducted by measuring relaxation parameters at different field strengths, has become an increasingly popular technique in recent years. This technique, known as field cycling, often uses expensive and large electromagnets. In this work we present a small, portable field cycling sensor. Fast field cycling is a technique that uses a varying magnetic field applied to a sample, polarising it at a high field, allowing it time to develop at a lower field and then collecting the data at the same initial high field. This causes changes in T1 and can reveal interesting proper ties of the samples not seen by traditional methods. A prototype portable magnetic resonance sensor that undertakes relaxometry measurements using fast field cycling has been developed using a combination of permanent magnets which has been used to conduct preliminary studies on a water sample. We demonstrate the effectiveness of this sensor by conducting measurements of T1 at different field strengths

The Data Privacy Compromise: Reconciling State and Federal Regulatory Regimes on the Path to Preemption

Today, it is easier than ever before for business entities to collect and sell our data, and most consumers lack comprehensive knowledge of how they can protect their data or recognize the true extent of potential exposure. Although data privacy regulation is gearing up among U.S. states, federal legislators have been stagnant in regard to passing a federal data privacy law. Without clearer, broader protections for consumers, many will be left to deal with overlapping laws and confusing procedures for pursuing legal remedies. The relationship between federal and state regulation is best maintained when Congress carefully balances the different roles of each. In the context of data privacy, some legislators believe that the states should enact their own laws without federal interference, as some already have, while others believe that federal preemption is imperative to achieving the most efficient protection for consumer data. As the pressure piles on for Congress to pass a federal privacy law, a balanced approach is key to moving forward. This Note proposes a happy medium and explores a multilayered approach to preemption to achieve a uniform baseline for protection without displacing the states’ valuable regulatory role in the data privacy sphere

A Reconfigurable Gate Architecture for Si/SiGe Quantum Dots

We demonstrate a reconfigurable quantum dot gate architecture that incorporates two interchangeable transport channels. One channel is used to form quantum dots and the other is used for charge sensing. The quantum dot transport channel can support either a single or a double quantum dot. We demonstrate few-electron occupation in a single quantum dot and extract charging energies as large as 6.6 meV. Magnetospectroscopy is used to measure valley splittings in the range of 35-70 microeV. By energizing two additional gates we form a few-electron double quantum dot and demonstrate tunable tunnel coupling at the (1,0) to (0,1) interdot charge transition.Comment: Related papers at http://pettagroup.princeton.ed

Scalable gate architecture for densely packed semiconductor spin qubits

We demonstrate a 12 quantum dot device fabricated on an undoped Si/SiGe heterostructure as a proof-of-concept for a scalable, linear gate architecture for semiconductor quantum dots. The device consists of 9 quantum dots in a linear array and 3 single quantum dot charge sensors. We show reproducible single quantum dot charging and orbital energies, with standard deviations less than 20% relative to the mean across the 9 dot array. The single quantum dot charge sensors have a charge sensitivity of 8.2 x 10^{-4} e/root(Hz) and allow the investigation of real-time charge dynamics. As a demonstration of the versatility of this device, we use single-shot readout to measure a spin relaxation time T1 = 170 ms at a magnetic field B = 1 T. By reconfiguring the device, we form two capacitively coupled double quantum dots and extract a mutual charging energy of 200 microeV, which indicates that 50 GHz two-qubit gate operation speeds are feasible