The ecology of the intestinal flora in a changing environment Final report

Resume of publications and recommendations from symposium on intestinal flora ecology in changing environment

Research on long term biological isolation of primates and mice. Volume 4 - The literature search, appendix M Final report

Literature search for effects of intestinal microflora on host organism

An evaluation of nutritional markers, volume 2

Use of nutritional markers for studies of food intake, passage, and absorption in gastrointestinal track of humans and animal

Research on long term biological isolation of primates and mice, volume 1 Final report, 7 Jan. 1969 - 7 Jan. 1970

Long term effects of biological isolation on monkeys and mice with application to prolonged space fligh

Energy and Nutrient Intake Monitoring

A passive system to determine the in-flight intake of nutrients is developed. Nonabsorbed markers placed in all foods in proportion to the nutrients selected for study are analyzed by neutron activation analysis. Fecal analysis for each market indicates how much of the nutrients were eaten and apparent digestibility. Results of feasibility tests in rats, mice, and monkeys indicate the diurnal variation of several markers, the transit time for markers in the alimentary tract, the recovery of several markers, and satisfactory use of selected markers to provide indirect measurement of apparent digestibility. Recommendations are provided for human feasibility studies

Apollo diet evaluation, Volume 1

Nutritional evaluation of Apollo diets and gnotobiological study of mice having diets with limited microflor

Stem-Cell-like Qualities of Immune Memory; CD4+ T Cells Join the Party

Similar to hematopoietic stem cells, memory lymphocytes self-renew, while their clonally expanded effector progeny differentiate to fight infection and tumors. Recently, Muranski et al. (2011) report in Immunity that a subset of Th17 effector cells function as memory cells and retain stem cell properties

The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria

Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm. The outer membrane contains various protein channels, called porins, which are involved in the influx of various compounds, including several classes of antibiotics. Bacterial adaptation to reduce influx through porins is an increasing problem worldwide that contributes, together with efflux systems, to the emergence and dissemination of antibiotic resistance. An exciting challenge is to decipher the genetic and molecular basis of membrane impermeability as a bacterial resistance mechanism. This Review outlines the bacterial response towards antibiotic stress on altered membrane permeability and discusses recent advances in molecular approaches that are improving our knowledge of the physico-chemical parameters that govern the translocation of antibiotics through porin channel

ISOTOPIC COMPOSITION OF LIGHT NUCLEI IN COSMIC RAYS: RESULTS FROM AMS-01

The variety of isotopes in cosmic rays allows us to study different aspects of the processes that cosmic rays undergo between the time they are produced and the time of their arrival in the heliosphere. In this paper, we present measurements of the isotopic ratios [superscript 2]H/[superscript 4]He, [superscript 3]He/[superscript 4]He, [superscript 6]Li/[superscript 7]Li, [superscript 7]Be/([superscript 9]Be+[superscript 10]Be), and [superscript 10]B/[superscript 11]B in the range 0.2-1.4 GeV of kinetic energy per nucleon. The measurements are based on the data collected by the Alpha Magnetic Spectrometer, AMS-01, during the STS-91 flight in 1998 June.United States. Dept. of EnergyMassachusetts Institute of Technolog

Isotopic Composition of Light Nuclei in Cosmic Rays: Results from AMS-01

The variety of isotopes in cosmic rays allows us to study different aspects of the processes that cosmic rays undergo between the time they are produced and the time of their arrival in the heliosphere. In this paper we present measurements of the isotopic ratios 2H/4He, 3He/4He, 6Li/7Li, 7Be/(9Be+10Be) and 10B/11B in the range 0.2-1.4 GeV of kinetic energy per nucleon. The measurements are based on the data collected by the Alpha Magnetic Spectrometer, AMS-01, during the STS-91 flight in 1998 June.Comment: To appear in ApJ. 12 pages, 11 figures, 6 table