Physics of Proximity Josephson Sensor

We study the proximity Josephson sensor (PJS) in both bolometric and calorimetric operation and optimize it for different temperature ranges between 25 mK and a few Kelvin. We investigate how the radiation power is absorbed in the sensor and find that the irradiated sensor is typically in a weak nonequilibrium state. We show in detail how the proximity of the superconductors affects the device response: for example via changes in electron-phonon coupling and out-of-equilibrium noise. In addition, we estimate the applicability of graphene as the absorber material.Comment: 13 pages, 11 figures, submitted to Journal of Applied Physics, v2: Addition of a new section discussing the radiation coupling to the device, several minor change

Theory of temperature fluctuation statistics in superconductor-normal metal tunnel structures

We describe the statistics of temperature fluctuations in a SINIS structure, where a normal metal island (N) is coupled by tunnel junctions (I) to two superconducting leads (S). We specify conditions under which this structure exhibits manifestly non-Gaussian fluctuations of temperature. We consider both the Gaussian and non-Gaussian regimes of these fluctuations, and the current fluctuations that are caused by the fluctuating temperature. We also describe a measurement setup that could be used to observe the temperature fluctuations.Comment: 10 pages, 9 figures, final versio

Fully Overheated Single-Electron Transistor

We consider the fully overheated single-electron transistor, where the heat balance is determined entirely by electron transfers. We find three distinct transport regimes corresponding to cotunneling, single-electron tunneling, and a competition between the two. We find an anomalous sensitivity to temperature fluctuations at the crossover between the two latter regimes that manifests in an exceptionally large Fano factor of current noise.Comment: 6 pages, 3 figures, includes Appendi

Charge transport in ballistic multiprobe graphene structures

We study the the transport properties of multiterminal ballistic graphene samples, concentrating on the conductance matrix, fluctuations and cross-correlations. Far away from Dirac point, the current is carried mostly by propagating modes and the results can be explained with the conventional semiclassical picture familiar from ray optics, where electrons propagate along a single direction before scattering or reaching the terminals. However, close to the Dirac point the transport is due to evanescent modes which do not have to follow a rectilinear path. As we show in this Letter, this property of the evanescent modes influences the conductance matrix. However, at best it can be observed by measuring the cross correlations in an exchange Hanbury Brown-Twiss experiment.Comment: 5 pages, 5 figure

The association of adolescent fitness with cardiometabolic diseases in late adulthood: A 45-year longitudinal study

This work was supported by Emil Aaltonen Foundation under Grant 210097 O, Ellen ja Artturi Nyyssönen Foundation, and Juho Vainio Foundation under Grant 202300290.Objectives: The aim of this study was to examine the associations of adolescent cardiorespiratory fitness (CRF), muscular fitness (MF), and speed-agility fitness (SA) with middle-aged cardiometabolic disease risk and explore sex differences. Methods: This 45-year prospective cohort study examined the associations be- tween objectively measured fitness at adolescence (12–19 years) and physician- ascertained diabetes mellitus, elevated blood pressure (BP), and coronary heart disease reported either in early (37–44 years) or late (57–64 years) middle age, and self-measurement of waist circumference (WC) in late middle age. Fitness meas- urements for healthy adolescents in baseline included CRF (1.5 km [girls] and 2 km [boys] run), MF (standing broad jump, sit-ups, pull-ups [boys], and flexed- arm hang [girls]), and SA (50 m dash and 4 × 10 m shuttle run). Logistic regression and general linear models were adjusted for baseline age, sex, and body mass index (BMI), involving data from baseline and at least one follow-up measure- ment (N up to 1358, 47% males). Results: Adolescent CRF was inversely, and regardless of adiposity, associ- ated with middle age accumulated burden of cardiometabolic conditions in the whole sample (N = 562, ß = −0.10, 95% confidence intervals [CI] [−0.18, −0.03], p = 0.006), and elevated BP in females (N = 256, OR = 0.71, 95% CI [0.51, 0.91]). Overall, we observed stronger associations in females than in males. An inverse association of adolescent MF and SA with middle-aged WC was observed, but it did not show as consistent associations as with CRF. Conclusions: In this study, adolescent fitness, particularly CRF, was inversely as- sociated with the burden of cardiometabolic conditions up to 45 years. Promotion of fitness in youth may be beneficial in preventing adulthood cardiometabolic diseases.Emil Aaltonen Foundation 210097 OEllen ja Artturi Nyyssönen FoundationJuho Vainio Foundation 20230029

Giant current fluctuations in an overheated single electron transistor

Interplay of cotunneling and single-electron tunneling in a thermally isolated single-electron transistor (SET) leads to peculiar overheating effects. In particular, there is an interesting crossover interval where the competition between cotunneling and single-electron tunneling changes to the dominance of the latter. In this interval, the current exhibits anomalous sensitivity to the effective electron temperature of the transistor island and its fluctuations. We present a detailed study of the current and temperature fluctuations at this interesting point. The methods implemented allow for a complete characterization of the distribution of the fluctuating quantities, well beyond the Gaussian approximation. We reveal and explore the parameter range where, for sufficiently small transistor islands, the current fluctuations become gigantic. In this regime, the optimal value of the current, its expectation value, and its standard deviation differ from each other by parametrically large factors. This situation is unique for transport in nanostructures and for electron transport in general. The origin of this spectacular effect is the exponential sensitivity of the current to the fluctuating effective temperature.Comment: 10 pages, 11 figure

Nonequilibrium characteristics in all-superconducting tunnel structures

We study the nonequilibrium characteristics of superconducting tunnel structures in the case when one of the superconductors is a small island confined between large superconductors. The state of this island can be probed for example via the supercurrent flowing through it. We study both the far-from-equilibrium limit when the rate of injection for the electrons into the island exceeds the energy relaxation inside it, and the quasiequilibrium limit when the electrons equilibrate between themselves. We also address the crossover between these limits employing the collision integral derived for the superconducting case. The clearest signatures of the nonequilibrium limit are the anomalous heating effects seen as a supercurrent suppression at low voltages, and the hysteresis at voltages close to the gap edge $2\Delta/e$, resulting from the peculiar form of the nonequilibrium distribution function.Comment: 8 pages, 10 figure

Outside-host phage therapy as a biological control against environmental infectious diseases

Background: Environmentally growing pathogens present an increasing threat for human health, wildlife and food production. Treating the hosts with antibiotics or parasitic bacteriophages fail to eliminate diseases that grow also in the outside-host environment. However, bacteriophages could be utilized to suppress the pathogen population sizes in the outside-host environment in order to prevent disease outbreaks. Here, we introduce a novel epidemiological model to assess how the phage infections of the bacterial pathogens affect epidemiological dynamics of the environmentally growing pathogens. We assess whether the phage therapy in the outside-host environment could be utilized as a biological control method against these diseases. We also consider how phage-resistant competitors affect the outcome, a common problem in phage therapy. The models give predictions for the scenarios where the outside-host phage therapy will work and where it will fail to control the disease. Parameterization of the model is based on the fish columnaris disease that causes significant economic losses to aquaculture worldwide. However, the model is also suitable for other environmentally growing bacterial diseases. Results: Transmission rates of the phage determine the success of infectious disease control, with high-transmission phage enabling the recovery of the host population that would in the absence of the phage go asymptotically extinct due to the disease. In the presence of outside-host bacterial competition between the pathogen and phage-resistant strain, the trade-off between the pathogen infectivity and the phage resistance determines phage therapy outcome from stable coexistence to local host extinction. Conclusions: We propose that the success of phage therapy strongly depends on the underlying biology, such as the strength of trade-off between the pathogen infectivity and the phage-resistance, as well as on the rate that the phages infect the bacteria. Our results indicate that phage therapy can fail if there are phage-resistant bacteria and the trade-off between pathogen infectivity and phage resistance does not completely inhibit the pathogen infectivity. Also, the rate that the phages infect the bacteria should be sufficiently high for phage-therapy to succeed.Peer reviewe

Field location and player roles as constraints on emergent 1-vs-1 interpersonal patterns of play in football

This study examined effects of player roles on interpersonal patterns of coordination that sustain decision-making in 1-vs-1 sub-phases of football in different field locations near the goal (left-, middle- and right zone). Participants were fifteen U-16 yrs players from a local competitive amateur team. To measure interpersonal patterns of coordination in the 1-vs-1 dyads we recorded: (i) the relative distance value between each attacker and defender to the centre of the goal, and (ii), the relative angle between the centre of the goal, each defender and attacker. Results revealed how variations in field locations near the goal (left-, middle- and right-zones) constrained the relative distance and relative angle values that emerged between them and the goal. It reveals that relative position of the goal is a key informational variable that sustained participants’ behaviours for dribbling and shooting. Higher values of relative distance and angle were observed in the middle zone, compared to other zones. Players’ roles also constitute a constraint on the interpersonal coordination for dribbling and shooting. Additionally, it seems that players’ foot preference constrains the dynamics of interpersonal patterns of coordination between participants, especially in left and right zones. The findings suggest that to increase participants’ opportunities for action, coaches should account with field positions, players’ roles and preference foot