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Nematic and Polar order in Active Filament Solutions

Using a microscopic model of interacting polar biofilaments and motor proteins, we characterize the phase diagram of both homogeneous and inhomogeneous states in terms of experimental parameters. The polarity of motor clusters is key in determining the organization of the filaments in homogeneous isotropic, polarized and nematic states, while motor-induced bundling yields spatially inhomogeneous structures.Comment: 4 pages. 3 figure

Concept study for a high-efficiency nanowire-based thermoelectric

Materials capable of highly efficient, direct thermal-to-electric energy conversion would have substantial economic potential. Theory predicts that thermoelectric efficiencies approaching the Carnot limit can be achieved at low temperatures in one-dimensional conductors that contain an energy filter such as a double-barrier resonant tunneling structure. The recent advances in growth techniques suggest that such devices can now be realized in heterostructured, semiconductor nanowires. Here we propose specific structural parameters for InAs/InP nanowires that may allow the experimental observation of near-Carnot efficient thermoelectric energy conversion in a single nanowire at low temperature

Rheology of Active Filament Solutions

We study the viscoelasticity of an active solution of polar biofilaments and motor proteins. Using a molecular model, we derive the constitutive equations for the stress tensor in the isotropic phase and in phases with liquid crystalline order. The stress relaxation in the various phases is discussed. Contractile activity is responsible for a spectacular difference in the viscoelastic properties on opposite sides of the order-disorder transition.Comment: 4 pages, 1 figur

Bridging the microscopic and the hydrodynamic in active filament solutions

Hydrodynamic equations for an isotropic solution of active polar filaments are derived from a microscopic mean-field model of the forces exchanged between motors and filaments. We find that a spatial dependence of the motor stepping rate along the filament is essential to drive bundle formation. A number of differences arise as compared to hydrodynamics derived (earlier) from a mesoscopic model where relative filament velocities were obtained on the basis of symmetry considerations. Due to the anisotropy of filament diffusion, motors are capable of generating net filament motion relative to the solvent. The effect of this new term on the stability of the homogeneous state is investigated.Comment: 7 pages, 2 figures, submitted to Europhys. Let

Diurnal water-pressure fluctuations: timing and pattern of termination below Bench Glacier, Alaska, USA

Observations from basal water-pressure sensors along the length of Bench Glacier, Alaska, USA, show that diurnal fluctuations of water pressure are seasonal and restricted to summer. Most notable about these fluctuations is their disappearance in the late summer and early autumn, long before the seasonal end of diurnal meltwater input. Here we present data documenting the end of diurnal water-pressure fluctuations during the 2002 and 2003 melt seasons. The end of diurnal fluctuations occurred abruptly in multiple boreholes spaced meters to kilometers apart. There was no obvious spatial progression of termination events, and a clear correlation with meteorological forcing or discharge in the outlet stream was not apparent. After diurnal pressure fluctuations ended, basal water pressure returned to a high, generally steady, value either in an irregular pattern or by a distinct increase. This high water pressure was interrupted by episodic, acyclic events throughout the autumn before becoming stable and high in winter

A Chandra View of the Normal SO Galaxy NGC 1332: II: Solar Abundances in the Hot Gas and Implications for SN Enrichment

We present spectral analysis of the diffuse emission in the normal, isolated, moderate-Lx S0 NGC 1332, constraining both the temperature profile and the metal abundances in the ISM. The characteristics of the point source population and the gravitating matter are discussed in two companion papers. The diffuse emission comprises hot gas, with an ~isothermal temperature profile (~0.5 keV), and emission from unresolved point-sources. In contrast with the cool cores of many groups and clusters, we find a small central temperature peak. We obtain emission-weighted abundance contraints within 20 kpc for several key elements: Fe, O, Ne, Mg and Si. The measured iron abundance (Z_Fe=1.1 in solar units; >0.53 at 99% confidence) strongly excludes the very sub-solar values often historically reported for early-type galaxies but agrees with recent observations of brighter galaxies and groups. The abundance ratios, with respect to Fe, of the other elements were also found to be ~solar, although Z_o/Z_Fe was significantly lower (<0.4). Such a low O abundance is not predicted by simple models of ISM enrichment by Type Ia and Type II supernovae, and may indicate a significant contribution from primordial hypernovae. Revisiting Chandra observations of the moderate-Lx, isolated elliptical NGC 720, we obtain similar abundance constraints. Adopting standard SNIa and SNII metal yields, our abundance ratio constraints imply 73+/-5% and 85+/-6% of the Fe enrichment in NGC 1332 and NGC 720, respectively, arises from SNIa. Although these results are sensitive to the considerable systematic uncertainty in the SNe yields, they are in good agreement with observations of more massive systems. These two moderate-Lx early-type galaxies reveal a consistent pattern of metal enrichment from cluster scales to moderate Lx/Lb galaxies. (abridged)Comment: 12 pages, 4 figures, accepted for publication in ApJ. Minor changes to match published versio

Diurnal fluctuations in borehole water levels: configuration of the drainage system beneath Bench Glacier, Alaska, USA

Water levels were measured in boreholes spaced along the entire length of Bench Glacier, Alaska, USA, for a period in excess of 2 years. Instrumented boreholes were arranged as nine pairs along the center line of the glacier and an orthogonal grid of 16 boreholes in a 3600 m2 region at the center of the ablation area. Dirunal fluctuations of the water levels were found to be restricted to the late melt season. Pairs of boreholes spaced along the length of the ablation area often exhibited similar fluctuations and diurnal changes in water levels. Three distinct and independent types of diurnal fluctuations in water level were observed in cluster of boreholes within the grid of boreholes. Head gradients suggest water did not flow between clusters,and a single tunnel connecting the boreholes could not explain the observed pattern of diunal water-level fluctuations. Inter-borehole and borehole-cluster connectivity suggests the cross-glacier width of influence of a segment of the drainage system connected to a borehole was limited to tens of meters. A drainage configuration whereby boreholes are connected to a somewhat distant tunnel by drainage pipes of differing lengths, often hundreds of meters, is shown with a numerical test to be a plausible explanation for the observed borehole behavior

PacBio assembly of a Plasmodium knowlesi genome sequence with Hi-C correction and manual annotation of the SICAvar gene family.

Plasmodium knowlesi has risen in importance as a zoonotic parasite that has been causing regular episodes of malaria throughout South East Asia. The P. knowlesi genome sequence generated in 2008 highlighted and confirmed many similarities and differences in Plasmodium species, including a global view of several multigene families, such as the large SICAvar multigene family encoding the variant antigens known as the schizont-infected cell agglutination proteins. However, repetitive DNA sequences are the bane of any genome project, and this and other Plasmodium genome projects have not been immune to the gaps, rearrangements and other pitfalls created by these genomic features. Today, long-read PacBio and chromatin conformation technologies are overcoming such obstacles. Here, based on the use of these technologies, we present a highly refined de novo P. knowlesi genome sequence of the Pk1(A+) clone. This sequence and annotation, referred to as the 'MaHPIC Pk genome sequence', includes manual annotation of the SICAvar gene family with 136 full-length members categorized as type I or II. This sequence provides a framework that will permit a better understanding of the SICAvar repertoire, selective pressures acting on this gene family and mechanisms of antigenic variation in this species and other pathogens