Doing Science: How to optimise patient and public involvement in your research

This paper considers how best to achieve patient and public involvement in research and how to get the most out of it http://ow.ly/R0hwV

Feasibility and benefits of laminar flow control on supersonic cruise airplanes

An evaluation was made of the applicability and benefits of laminar flow control (LFC) technology to supersonic cruise airplanes. Ancillary objectives were to identify the technical issues critical to supersonic LFC application, and to determine how those issues can be addressed through flight and wind-tunnel testing. Vehicle types studied include a Mach 2.2 supersonic transport configuration, a Mach 4.0 transport, and two Mach 2-class fighter concepts. Laminar flow control methodologies developed for subsonic and transonic wing laminarization were extended and applied. No intractible aerodynamic problems were found in applying LFC to airplanes of the Mach 2 class, even ones of large size. Improvements of 12 to 17 percent in lift-drag ratios were found. Several key technical issues, such as contamination avoidance and excresence criteria were identified. Recommendations are made for their resolution. A need for an inverse supersonic wing design methodology is indicated

Doing Science: How to optimise patient and public involvement in your research

This paper considers how best to achieve patient and public involvement in research and how to get the most out of it http://ow.ly/R0hw

Impact of low gravity on water electrolysis operation

Advanced space missions will require oxygen and hydrogen utilities for several important operations including the following: (1) propulsion; (2) electrical power generation and storage; (3) environmental control and life support; (4) extravehicular activity; (5) in-space manufacturing and (6) in-space science activities. An experiment suited to a Space Shuttle standard middeck payload has been designed for the Static Feed Water Electrolysis technology which has been viewed as being capable of efficient, reliable oxygen and hydrogen generation with few subsystem components. The program included: end use design requirements, phenomena to be studied, Space Shuttle Orbiter experiment constraints, experiment design and data requirements, and test hardware requirements. The objectives are to obtain scientific and engineering data for future research and development and to focus on demonstrating and monitoring for safety of a standard middeck payload

Yield and protein variation within a controlled traffic system

Controlled Traffic systems aim to minimise wheel traffic impact on the cropping system. In this study, on-farm research was employed to investigate the impact of several wheel tracks on grain yield and protein in a planter width within a 7-year-old Controlled Traffic Farming (CTF) system. This was achieved by using a plot harvester. Results from the study of grain sorghum (Sorghum bicolor) and maize (Zea mays) showed lower establishment rates adjacent to wheel tracks, resulting in lower yield and higher protein. Further studies investigating a change to a system with fewer wheel tracks show that reducing the number of wheel tracks appears to have led to increased grain yield

A phenomenological model of the superconducting state of the Bechgaard salts

We present a group theoretical analysis of the superconducting state of the Bechgaard salts, e.g., (TMTSF)_2PF_6 or (TMTSF)_2ClO_6. We show that there are eight symmetry distinct superconducting states. Of these only the (fully gapped, even frequency, p-wave, triplet) 'polar state' is consistent with the full range of the experiments on the Bechgaard salts. The gap of the polar state is d(k) (psi_uk,0,0), where psi_uk may be any odd parity function that is translationally invariant.Comment: 4 pages, no figure

The Michigan aero instructional software project - TODOR meets the world-wide web

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76121/1/AIAA-1998-2790-621.pd

Epileptic high-frequency network activity in a model of non-lesional temporal lobe epilepsy

High-frequency cortical activity, particularly in the 250–600 Hz (fast ripple) band, has been implicated in playing a crucial role in epileptogenesis and seizure generation. Fast ripples are highly specific for the seizure initiation zone. However, evidence for the association of fast ripples with epileptic foci depends on animal models and human cases with substantial lesions in the form of hippocampal sclerosis, which suggests that neuronal loss may be required for fast ripples. In the present work, we tested whether cell loss is a necessary prerequisite for the generation of fast ripples, using a non-lesional model of temporal lobe epilepsy that lacks hippocampal sclerosis. The model is induced by unilateral intrahippocampal injection of tetanus toxin. Recordings from the hippocampi of freely-moving epileptic rats revealed high-frequency activity (4100 Hz), including fast ripples. High-frequency activity was present both during interictal discharges and seizure onset. Interictal fast ripples proved a significantly more reliable marker of the primary epileptogenic zone than the presence of either interictal discharges or ripples (100–250 Hz). These results suggest that fast ripple activity should be considered for its potential value in the pre-surgical workup of non-lesional temporal lobe epilepsy

Kinetics and Mechanisms of Oxidation of Hemoprotein Model Compounds

The kinetics of reaction of oxyheme complexes with dithionite ion and with deoxyheme were studied. Because rates of autooxidation of oxyheme complexes were inversly proportional to oxygen pressure and proportional to the square of the total heme concentration, it was concluded that the reaction proceeds through Heme- 00-Heme as suggested by Cohen and Caughey. The direct reaction of dithionite ion with oxyheme complexes accords with the Fe+o 2- · formulation of the iron-oxygen bond

Kinetics and Mechanisms of Oxidation of Hemoprotein Model Compounds

The kinetics of reaction of oxyheme complexes with dithionite ion and with deoxyheme were studied. Because rates of autooxidation of oxyheme complexes were inversly proportional to oxygen pressure and proportional to the square of the total heme concentration, it was concluded that the reaction proceeds through Heme- 00-Heme as suggested by Cohen and Caughey. The direct reaction of dithionite ion with oxyheme complexes accords with the Fe+o 2- · formulation of the iron-oxygen bond