JOB BUILDER remote batch processing subsystem

The functions of the JOB BUILDER remote batch processing subsystem are described. Instructions are given for using it as a component of a display system developed by personnel of the System Programming Laboratory, Institute of Space Research, USSR Academy of Sciences

Structure of 5-nitro-2-tosylaminobenzaldehyde di(morpholin-4-yl)aminal Complex with Carbon Tetrachloride

The 5-nitro-2-tosylaminobenzaldehyde di(morpholin-4-yl)aminal forms a stable complex with carbon tetrachloride in the crystal phase. X-ray structural study of this complex indicates an essentially shortened intermolecular contact of 2.89 Å between the oxygen atom of the nitro group and one of the chlorine atom of the CCI4 molecule. Quantum-chemical calculations by semiempirical AMI method showed that the formation of such complex did not cause considerable decrease of system energy or change of charge distribution in molecules. It was supposed that this associate has van der Waals character

Electric field dependence of thermal conductivity of a granular superconductor: Giant field-induced effects predicted

The temperature and electric field dependence of electronic contribution to the thermal conductivity (TC) of a granular superconductor is considered within a 3D model of inductive Josephson junction arrays. In addition to a low-temperature maximum of zero-field TC K(T,0) (controlled by mutual inductance L_0 and normal state resistivity R_n), the model predicts two major effects in applied electric field: (i) decrease of the linear TC, and (ii) giant enhancement of the nonlinear (i.e., grad T-dependent) TC with [K(T,E)-K(T,0)]/K(T,0) reaching 500% for parallel electric fields E=E_T (E_T=S_0|grad T| is an "intrinsic" thermoelectric field). A possiblity of experimental observation of the predicted effects in granular superconductors is discussed.Comment: 5 LaTeX pages (jetpl.sty included), 2 EPS figures. To be published in JETP Letter

Structure of a bacterial type IV secretion core complex at subnanometre resolution

Type IV secretion (T4S) systems are able to transport DNAs and/or proteins through the membranes of bacteria. They form large multiprotein complexes consisting of 12 proteins termed VirB1-11 and VirD4. VirB7, 9 and 10 assemble into a 1.07 MegaDalton membrane-spanning core complex (CC), around which all other components assemble. This complex is made of two parts, the O-layer inserted in the outer membrane and the I-layer inserted in the inner membrane. While the structure of the O-layer has been solved by X-ray crystallography, there is no detailed structural information on the I-layer. Using high-resolution cryo-electron microscopy and molecular modelling combined with biochemical approaches, we determined the I-layer structure and located its various components in the electron density. Our results provide new structural insights on the CC, from which the essential features of T4S system mechanisms can be derived

Targeted JAM-C deletion in germ cells by Spo11-controlled Cre recombinase

Meiosis is a crucial process for the production of functional gametes. However, the biological significance of many genes expressed during the meiotic phase remains poorly understood, mainly because of the lethal phenotypes of the knockout mice. Functional analysis of such genes using the conditional knockout approach is hindered by the lack of suitable Cre transgenic lines. We describe here the generation of transgenic mice expressing Cre recombinase under the control of the meiotic Spo11 gene. Using LacZ-R26(loxP) and EYFP-R26(loxP) reporter mice, we show the specific expression and activity of Cre during meiosis in males and females. Spo11(Cre) mice were then crossed with floxed Nbs1 and JAM-C mice to produce conditional knockouts. A strong reduction of Nbs1 and JAM-C protein levels was found in the testis. Although Nbs1-deleted mice developed minor gonadal abnormalities, JAM-C-knockout mice showed a spermiogenetic arrest, as previously described for the null mice. These results provide strong evidence that Spo11(Cre) transgenic mice represent a powerful tool for deleting genes of interest specifically in meiotic and/or in postmeiotic germ cells

Special features of the 9^9Be→\to2He fragmentation in emulsion at an energy of 1.2~A~GeV

The results of investigations of the relativistic $^9$Be nucleus fragmentation in emulsion which entails the production of two He fragments of an energy of 1.2~A~GeV are presented. The results of the angular measurements of the $^9$Be$\to$2He events are analyzed. The $^9$Be$\to^8$Be+n fragmentation channel involving the $^8$Be decay from the ground (0$^+$) and the first excited (2$^+$) states to two $\alpha$ particles is observed to be predominant.Comment: 10 pages, 6 figures, conference: Conference on Physics of Fundamental Interactions, Moscow, Russia, 5-9 Dec 2005 (Author's translation

ИНВЕСТИЦИОННАЯ КОНЪЮНКТУРА В РОССИЙСКОЙ ПРОМЫШЛЕННОСТИ

The actual deficiency of investment into Russian industry innovative development increases its technological drag from industries of countries with developed markets. Although the rate of investment into real sectors of Russian economics mid 2000 was higher compared to the previous period, annual investment amounts were much lower than in 1990. At present, highest investment amounts are directed to industry extractive branches and to the commerce. Amounts invested to various economy branches do not correspond to their contribution to the country’sGross Added Product; particularly underinvested are manufacturing industry branches. At present, foreign share in the country economy total investment makes 15–18%. Recently, most interesting for foreigners was investment to machine-building branches with overwhelming part (for example, 90% in 2007–2008) of foreign investment into the machine-building industry being directed to creation of new automobile plants. Today, first place in the list of foreign investors’ preferences in Russia is taken by the machine-tool construction sector.Имеющий место дефицит инвестиций для инновационного развития российской промышленности увеличивает ее технологическое отставание от промышленности стран с развитыми рынками. Хотя в середине первой декады XXI столетия наблюдалось повышение темпов роста инвестиционной активности в реальном секторе экономики, по сравнению с предыдущим периодом, годовые объемы инвестиций оставались существенно ниже уровня 1990 г. В настоящее время наиболее высокие объемы инвестиций приходятся на добывающие отрасли и торговлю. Объемы инвестиций по отраслям не соответствуют их вкладу в валовую добавленную стоимость; очевидна недоинвестированность обрабатывающей промышленности. Доля иностранных инвестиций в общем их объеме по стране составляет около 15–18%. До недавнего времени наибольший интерес для иностранцев представляли инвестиции в машиностроение, при этом, например, в 2007–2008 гг. около 90% объема иностранных инвестиций в отрасли машиностроения были направлены на создание новых автомобильных предприятий. В настоящее время первое место в рейтинге предпочтений зарубежных компаний занимает станкостроение

Electromagnetic dissociation of relativistic 8^8B nuclei in nuclear track emulsion

Experimental data on fragmentation channels in peripheral interactions of $^8$B nuclei in nuclear track emulsions are presented. A detailed analysis made it possible to justify selections of events of the electromagnetic-dissociation process $^8$B $\to^7$Be + \emph{p} and to estimate its cross section. Events of $^{10}$C peripheral dissociation that were observed in the same exposure are described.Comment: 12 pages, 10 figures, 4 tables, Published in Phys.Atom.Nucl.72:690-701,200

Fragmentation of relativistic nuclei in peripheral interactions in nuclear track emulsion

The technique of nuclear track emulsions is used to explore the fragmentation of light relativistic nuclei down to the most peripheral interactions - nuclear "white" stars. A complete pattern of therelativistic dissociation of a $^8$B nucleus with target fragment accompaniment is presented. Relativistic dissociation $^{9}$Be$\to2\alpha$ is explored using significant statistics and a relative contribution of $^{8}$Be decays from 0$^+$ and 2$^+$ states is established. Target fragment accompaniments are shown for relativistic fragmentation $^{14}$N$\to$3He+H and $^{22}$Ne$\to$5He. The leading role of the electromagnetic dissociation on heavy nuclei with respect to break-ups on target protons is demonstrated in all these cases. It is possible to conclude that the peripheral dissociation of relativistic nuclei in nuclear track emulsion is a unique tool to study many-body systems composed of lightest nuclei and nucleons in the energy scale relevant for nuclear astrophysics.Comment: 15 pages, 4 figures, 4 tables, conference: Relativistic nuclear physics: from Nuclotron to LHC energies, Kiev, June 18-22, 200