Performance of the cross-product steering law for the transearth injection phase

Steering law for transearth injection between circular lunar orbit and vector

Literature-based priors for gene regulatory networks

Motivation: The use of prior knowledge to improve gene regulatory network modelling has often been proposed. In this paper we present the first research on the massive incorporation of prior knowledge from literature for Bayesian network learning of gene networks. As the publication rate of scientific papers grows, updating online databases, which have been proposed as potential prior knowledge in past rese-arch, becomes increasingly challenging. The novelty of our approach lies in the use of gene-pair association scores that describe the over-lap in the contexts in which the genes are mentioned, generated from a large database of scientific literature, harnessing the information contained in a huge number of documents into a simple, clear format. Results: We present a method to transform such literature-based gene association scores to network prior probabilities, and apply it to learn gene sub-networks for yeast, E. coli and Human organisms. We also investigate the effect of weighting the influence of the prior know-ledge. Our findings show that literature-based priors can improve both the number of true regulatory interactions present in the network and the accuracy of expression value prediction on genes, in comparison to a network learnt solely from expression data. Networks learnt with priors also show an improved biological interpretation, with identified subnetworks that coincide with known biological pathways. Contact

Mass Predictions for Pseudoscalar JPC=0−+J^{PC}=0^{-+} Charmonium and Bottomonium Hybrids in QCD Sum-Rules

Masses of the pseudoscalar $(J^{PC}=0^{-+})$ charmonium and bottomonium hybrids are determined using QCD Laplace sum-rules. The effects of the dimension-six gluon condensate are included in our analysis and result in a stable sum-rule analysis, whereas previous studies of these states were unable to optimize mass predictions. The pseudoscalar charmonium hybrid is predicted to have a mass of approximately 3.8 GeV and the corresponding bottomonium prediction is 10.6 GeV. Calculating the full correlation function, rather than only the imaginary part, is shown to be necessary for accurate formulation of the sum-rules. The charmonium hybrid mass prediction is discussed within the context of the X Y Z resonances.Comment: 10 pages, 7 embedded figures. Analysis extended and refined in v

Palatable Meal Anticipation in Mice

The ability to sense time and anticipate events is a critical skill in nature. Most efforts to understand the neural and molecular mechanisms of anticipatory behavior in rodents rely on daily restricted food access, which induces a robust increase of locomotor activity in anticipation of daily meal time. Interestingly, rats also show increased activity in anticipation of a daily palatable meal even when they have an ample food supply, suggesting a role for brain reward systems in anticipatory behavior, and providing an alternate model by which to study the neurobiology of anticipation in species, such as mice, that are less well adapted to "stuff and starve" feeding schedules. To extend this model to mice, and exploit molecular genetic resources available for that species, we tested the ability of wild-type mice to anticipate a daily palatable meal. We observed that mice with free access to regular chow and limited access to highly palatable snacks of chocolate or “Fruit Crunchies” avidly consumed the snack but did not show anticipatory locomotor activity as measured by running wheels or video-based behavioral analysis. However, male mice receiving a snack of high fat chow did show increased food bin entry prior to access time and a modest increase in activity in the two hours preceding the scheduled meal. Interestingly, female mice did not show anticipation of a daily high fat meal but did show increased activity at scheduled mealtime when that meal was withdrawn. These results indicate that anticipation of a scheduled food reward in mice is behavior, diet, and gender specific

Toxic ferns of Western Australia

Botanical descriptions and notes on the distribution of six species of ferns are given. These plants contain the enzyme thiaminase, which may induce thiamin deficiency, or other constituents toxic to animals. The clinical signs of both thiamin deficiency and fern toxicity in affected livestock are described

A novel design process of low cost 3D printed ambidextrous finger designed for an ambidextrous robotic hand

This paper presents the novel mechanical design of an ambidextrous finger specifically designed for an ambidextrous anthropomorphic robotic hand actuated by pneumatic artificial muscles. The ambidextrous nature of design allows fingers to perform both left and right hand movements. The aim of our design is to reduce the number of actuators, increase the range of movements with best possible range ideally greater than a common human finger. Four prototypes are discussed in this paper; first prototype is focused on the choice of material and to consider the possible ways to reduce friction. Second prototype is designed to investigate the tendons routing configurations. Aim of third and fourth prototype is to improve the overall performance and to maximize the grasping force. Finally, a unified design (Final design) is presented in great detail. Comparison of all prototypes is done from different angles to evaluate the best design. The kinematic features of intermediate mode have been analysed to optimize both the flexibility and the robustness of the system, as well as to minimize the number of pneumatic muscles. The final design of an ambidextrous finger has developed, tested and 3D printed

Constraints on Higher-Order Perturbative Corrections in b→ub\to u Semileptonic Decays from Residual Renormalization-Scale Dependence

The constraint of a progressive decrease in residual renormalization scale dependence with increasing loop order is developed as a method for obtaining bounds on unknown higher-order perturbative corrections to renormalization-group invariant quantities. This technique is applied to the inclusive semileptonic process $b\to u \bar\nu_\ell\ell^-$ (explicitly known to two-loop order) to obtain bounds on the three- and four-loop perturbative coefficients that are not accessible via the renormalization group. Using the principle of minimal sensitivity, an estimate is obtained for the perturbative contributions to $\Gamma(b\to u \bar\nu_\ell\ell^-)$ that incorporates theoretical uncertainty from as-yet-undetermined higher order QCD corrections.Comment: latex2e using amsmath, 8 pages, 4 embedded eps figures. Revised version contains an additional figure and accompanying revision

Applications of Small Satellites for Defense Space Communication Systems and Technology Development: Pegasus Flight-2 and the Launch of Microsat

DARPA\u27s seven Microsats were placed into orbit on the second flight of the Pegasus. The Microsat program objective is to assess the tactical utility of small, low-cost communications satellites. This paper describes the changes made to the Pegasus since its first flight, provides an overview of the Microsat demonstration program, and outlines the preliminary results of the Pegasus launch. Finally, the near-term Army and Navy demonstration plans for Microsat are discussed

Brown Dwarfs in the Pleiades Cluster. III. A deep IZ survey

We present the results of a deep CCD-based IZ photometric survey of a ~1 sq. deg area in the central region of the Pleiades Galactic open cluster. The magnitude coverage of our survey (from I~17.5 down to 22) allows us to detect substellar candidates with masses between 0.075 and 0.03 Msol. Details of the photometric reduction and selection criteria are given. Finder charts prepared from the I-band images are provided.Comment: 11 pages with 8 figures, 4 of them are finder charts given in gif format. Accepted for publication in A&AS. Also available at http://www.iac.es/publicaciones/preprints.htm

A brief description of geological and geophysical exploration of the Marysville geothermal area

Extensive geological and geophysical surveys were carried out at the Marysville geothermal area during 1973 and 1974. The area has high heat flow (up to microcalories per square centimeter-second, a negative gravity anomaly, high electrical resistivity, low seismic ground noise, and nearby microseismic activity. Significant magnetic and infrared anomalies are not associated with the geothermal area. The geothermal anomaly occupies the axial portion of a dome in Precambrian sedimentary rocks intruded by Cretaceous and Cenozoic granitic rocks. The results from a 2.4-km-deep test well indicate that the cause of the geothermal anomaly is hydrothermal convection in a Cenozoic intrusive. A maximum temperature of 95 C was measured at a depth of 500 m in the test well