ДО ПРОБЛЕМ ЕФЕКТИВНОСТІ МЕТАПАМ’ЯТІ.

У статті здійснено теоретичний аналіз поняття ефективності метапам’яті, визначено та узагальнено низку основних проблем, що стосуються її ефективного функціонування, а саме: динамічності та ситуативності метапам’яті, взаємовідношення метапам’яттєвого моніторингу та метапам’яттєвого контролю, значення метапам’яттєвих знань, самоефективності пам’яті, досвіду та навчання у ефективності метапам’яті, перенесення досліджень з експериментальної площини в умови академічної діяльності. (In this paper the theoretical analysis of the concept of metamemory efficiency was conducted. The author defines and summarizes a number of key issues related to its effective functioning, namely dynamics and situationality of metamemory, the relationship between metamemory monitoring and control, the importnace of metamemory knowledge, self-efficacy of memory, experience and training in metamemory efficiency. The transfer of studies from experimental field into academic activities is realised)

Швидкість читання та продуктивність відтворення тексту з паперових та електронних носіїв студентами

У статті проаналізовано співвідношення швидкості та продуктивності читання студентами, досліджено відмінність швидкості читання текстової інформації з паперових носіїв та моніторів ПК, з’ясовано, в якому випадку продуктивність відтворення тексту буде більшою: при опрацюванні тексту з паперових носіїв чи з електронних.(The artical analyzed the correlation of speed and efficiency of student's reading, investigated the difference between the speed of reading text information from papers and computer's monitors, found out in what case the efficiency of the text reproduction will be better: while processing the text from papers or from the computers.

PSYCHOSOMATIC DISORDERS IN PATIENTS WITH CHRONIC KIDNEY DISEASE

Objective: to study the psychological status of patients and disabled persons with chronic kidney disease. Materials and methods: 74 patients, invalids because of renal pathology, were included in the study. Psycho-diagnostic data were analyzed by parametric methods (Teilor’s and Spielberger’s tests, intellectual methods). Results: the majority of studied patients with chronic kidney disease (62%) had emotional and motivation disorders, in 38% of them the signs of asthenic state were observed in the clinical picture of psychologic disorders. Intensity of depression and anxiety symptoms significantly increased with the increase of chronic kidney disease severity (p<0.05 and p<0.01, respectively). Conclusions: emotional and motivation disorders were detected in more than a half of patients with chronic kidney disease (62%), and 38% of patients showed the signs of asthenic state manifested by the decrease of functional abilities in performing daily living activities

Complexation of Ammonia Boranes with Al3+

Ammonia borane, NH3BH3 (AB), is very attractive for hydrogen storage; however, it dehydrogenates exothermally, producing a mixture of polymeric products with limited potential for direct rehydrogenation. Recently, it was shown that AB complexed with Al3+ in Al(BH4)3·AB endothermically dehydrogenates to a single product identified as Al(BH4)3·NHBH, with the potential for direct rehydrogenation of AB. Here we explore the reactivity of AB-derived RNH2BH3 (R = −CH3, −CH2−) with AlX3 salts (X = BH4–, Cl–), aiming to extend the series to different anions and to enlarge the stability window for Al(BH4)3·NRBH. Three novel complexes were identified: Al(BH4)3·CH3NH2BH3 having a molecular structure similar to that of Al(BH4)3·AB but different dehydrogenation properties, as well as [Al(CH3NH2BH3)2Cl2][AlCl4] and [Al(NH2CH2CH2NH2)(BH4)2][Al(BH4)4], rare examples of Al3+ making part of the cations and anions simultaneously. The latter compounds are of interest in the design of novel electrolytes for Al-based batteries. The coordination of two ABs to a single Al atom opens a route to materials with higher hydrogen content

A Zirconium Metal-Organic Framework with SOC Topological Net for Catalytic Peptide Bond Hydrolysis

The discovery of nanozymes for selective cleavage of proteins would boost the emerging areas of modern proteomics, however, the development of efficient and reusable artificial catalysts for peptide bond hydrolysis is challenging. Here we report the detailed catalytic properties of a microporous zirconium carboxylate metal-organic framework, MIP-201, in promoting peptide bond hydrolysis in a simple dipeptide, as well as in horse-heart myoglobin (Mb) protein that consists of 153 amino acids. We demonstrate that MIP-201 features an excellent catalytic activity and selectivity, a good tolerance toward reaction conditions covering a wide range of different pH values, and importantly, an exceptional recycling ability associated with easy regeneration process. Taking into account the excellent catalytic performance of MIP-201 and its other advantages such as 6-connected Zr6 cluster active sites, the green, scalable and cost-effective synthesis, and an outstanding chemical and architectural stability, our finding suggests that MIP-201 may be a promising and practical alternative to the current commercially available catalysts for peptide bond hydrolysis.</div

A zirconium metal-organic framework with SOC topological net for catalytic peptide bond hydrolysis

International audienceThe discovery of nanozymes for selective fragmentation of proteins would boost the emerging areas of modern proteomics, however, the development of efficient and reusable artificial catalysts for peptide bond hydrolysis is challenging. Here we report the catalytic properties of a zirconium metal-organic framework, MIP-201, in promoting peptide bond hydrolysis in a simple dipeptide, as well as in horse-heart myoglobin (Mb) protein that consists of 153 amino acids. We demonstrate that MIP-201 features excellent catalytic activity and selectivity, good tolerance toward reaction conditions covering a wide range of pH values, and importantly, exceptional recycling ability associated with easy regeneration process. Taking into account the catalytic performance of MIP-201 and its other advantages such as 6-connected Zr 6 cluster active sites, the green, scalable and cost-effective synthesis, and good chemical and architectural stability, our findings suggest that MIP-201 may be a promising and practical alternative to commercially available catalysts for peptide bond hydrolysis