Strong Forms of b-Continuous Multifunctions

In this paper we have introduced strong forms of b-continuous multifunctions namely b#-multicontinuity and *b-multicontinuity and studied their properties and characterizations. Also investigate the relationship with other type of functions with suitable examples

Transmigration of copper T presenting as abdominal wall mass: a case report

Copper T is one of the widely used intra uterine contraceptive devices due to its safe, effective and reversible nature. It has also been widely used as it is cost effective too. Copper T is usually inserted immediate post-partum, post abortal, during the proliferative phase of any menstrual cycle or 6 to 8 weeks following post-partum. Complications associated with use of Copper T include heavy menstrual bleeding, pelvic inflammatory disease, uterine perforation, displacement and rarely, transmigration. Post-insertion of copper T, women need to have regular follow up visits to prevent such complications. Patients should be advised to check for the presence of threads periodically. Considerable number of patients with transmigration of copper T has been reported in literature. Sites into which transmigration has been reported include broad ligament, ovarian fossa, urinary bladder, sigmoid colon, rectum, peritoneum, omentum, pouch of douglas, retro peritoneal space, iliac veins, ovaries, appendix and rarely in the abdominal wall. Transmigrated copper T may be diagnosed with ultrasonogram, X-ray and CT scan. Copper containing intra-uterine devices are known to provoke inflammatory reactions and symptoms depending upon the sites to which they have been transmigrated. Hence, we should resort to early intervention and remove the misplaced copper IUCD at the earliest. Here, we are reporting a rare case of transmigration of copper T into the anterior abdominal wall elaborating on various facets of copper T including its advent, incidence of use, efficient diagnosis and well-planned retrieval.

Rifampicin-induced renal toxicity during retreatment of patients with pulmonary tuberculosis

Rifampicin is a crucial component of treatment regimens for tuberculosis and has been in use since the early 1970’s. It is usually considered safe. Rarely life-threatening complications like acute renal failure or acute thrombocytopaenia may manifest during treatment with rifampicin. In our experience at the Tuberculosis Research Centre of treating more than 8000 pulmonary and extrapulmonary tuberculosis patients with rifampicin-containing regimens over the last 30 years, we are reporting 3 cases of probably rifampicininduced acute renal failure. Despite extreme therapeutic safety of this drug the clinician must be aware of this rare complication, which if detected early is completely reversible

A review on energy and cost effective phase separated pretreatment of biosolids

Extracellular Polymeric Substances (EPS) existent in anaerobic sludge proves to be a barrier for sludge liquefaction and biomass lysis efficiency. Hence EPS deaggregation heightens the surface area for the subsequent pretreatment thereby uplifting the sludge disintegration and biomethanation rate. This review documents the role of EPS and its components which inhibits sludge hydrolysis and also the various phase separated pretreatment methods available with its disintegration mechanism to enhance the biomass lysis and methane production rate. It also illustrates the effects of phase separated pretreatment on the sludge disintegration rate which embodies two phases-floc disruption and cell lysis accompanied by their computation through biomethane potential assay and fermentation analysis comprehensively. Additionally, energy balance study and cost analysis requisite for successful implementation of a proposed phase separated pretreatment on a pilot scale level and their challenges are also reviewed. Overall this paper documents the potency of phase separated pretreatment for full scale approach.publishedVersio

Ocular changes in primary hypothyroidism

<p>Abstract</p> <p>Background</p> <p>To determine the ocular changes related to hypothyrodism in newly diagnosed patients without orbitopathy.</p> <p>Findings</p> <p>Thirty-three patients diagnosed to have primary overt hypothyroidism were enrolled in the study. All subjects were assigned to underwent central corneal thickness (CCT), anterior chamber volume, depth and angle measurements with the Scheimpflug camera (Pentacam, Oculus) and cup to disc ratio (C/D), mean retinal thickness and mean retinal nerve fiber layer (RNFL) thickness measurements with optical coherence tomography (OCT) in addition to ophthalmological examination preceeding the replacement therapy and at the 1^st, 3^rdand 6^thmonths of treatment.</p> <p>The mean age of the patients included in the study were 40.58 ± 1.32 years. The thyroid hormone levels return to normal levels in all patients during the follow-up period, however the mean intraocular pressure (IOP) revealed no significant change. The mean CCT was 538.05 ± 3.85 μ initially and demonstrated no statistically significant change as the anterior chamber volume, depth and angle measurements did. The mean C/D ratio was 0.29 ± 0.03 and the mean retinal thickness was 255.83 ± 19.49 μ initially and the treatment did not give rise to any significant change. The mean RNFL thickness was also stable during the control visits, so no statistically significant change was encountered.</p> <p>Conclusions</p> <p>Neither hypothyroidism, nor its replacement therapy gave rise to any change of IOP, CCT, anterior chamber parameters, RNFL, retinal thickness and C/D ratio.</p

THREE-DIMENSIONAL QUANTITATIVE STRUCTURE–ACTIVITY RELATIONSHIPS MODELING STUDIES OF PHYTOCHEMICALS FROM BRASSICACEAE AS POTENT INHIBITORS AGAINST TUMOR INFLAMMATION

Objective: The aim of this study was to develop a three-dimensional quantitative structure–activity relationships (3D-QSARs) model for studying theinteraction of different phytochemicals with nuclear factor kappa B (NF-ĸB) inducing kinase, a major regulator in tumor inflammation.Methods: Different phytochemicals (ligands) from Brassicaceae were selected and tested for Lipinski's rule of five and further analyzed using interaction studies (docking) to identify the binding site in the target protein. Ligands with best fit were made to pass through ADMET filter, and the nontoxic ligands were selected based on the pIC50 values.Results: The 3D-QSARs of the ligands were designed using comparative molecular field analysis, and glucoraphanin was found to be stable and fit after subjecting for molecular dynamics simulation with annealing studies.Conclusion: Thus, the model may be prospectively used in drug design to find possible inhibitors of NF-ĸB, which plays a key prominent role in cancer inflammation.Keywords: Three-dimensional quantitative structure–activity relationships, Brassica oleracea, Simulation, Annealing, Nuclear factor kappa B kinase

Three-body decay of 6^{6}Be

Three-body correlations for the ground-state decay of the lightest two-proton emitter $^{6}$Be are studied both theoretically and experimentally. Theoretical studies are performed in a three-body hyperspherical-harmonics cluster model. In the experimental studies, the ground state of $^{6}$Be was formed following the $\alpha$ decay of a $^{10}$C beam inelastically excited through interactions with Be and C targets. Excellent agreement between theory and experiment is obtained demonstrating the existence of complicated correlation patterns which can elucidate the structure of $^{6}$Be and, possibly, of the A=6 isobar.Comment: 17 pages, 21 figures, 5 table

Astrophysical S factor for the radiative capture 12N(p,gamma)13O determined from the 14N(12N,13O)13C proton transfer reaction

The cross section of the radiative proton capture reaction on the drip line nucleus 12N was investigated using the Asymptotic Normalization Coefficient (ANC) method. We have used the 14N(12N,13O)13C proton transfer reaction at 12 MeV/nucleon to extract the ANC for 13O -> 12N + p and calculate from it the direct component of the astrophysical S factor of the 12N(p,gamma)13O reaction. The optical potentials used and the DWBA analysis of the proton transfer reaction are discussed. For the entrance channel, the optical potential was inferred from an elastic scattering measurement carried out at the same time with the transfer measurement. From the transfer, we determined the square of the ANC, C^2(13Og.s.) = 2.53 +/- 0.30 fm-1, and hence a value of 0.33(4) keVb was obtained for the direct astrophysical S factor at zero energy. Constructive interference at low energies between the direct and resonant captures leads to an enhancement of Stotal(0) = 0.42(5) keVb. The 12N(p,gamma)13O reaction was investigated in relation to the evolution of hydrogen-rich massive Population III stars, for the role that it may play in the hot pp-chain nuclear burning processes, possibly occurring in such objects.Comment: 15 pages, 10 figures, 3 tables submitted to Phys. Rev.