Herbage intake in Danish Jersey and Danish Holstein steers on perennial ryegrass/white clover pasture

The objective of this study was to estimate herbage intake in Danish Friesian and Danish Jersey steers at an age of 8-9 months on ryegrass / white clover pasture. The steers were turned out on pasture in late April and herbage intake was estimated in June in steers of a mean live weight (± S.D.) of 264 ± 14 kg and 185 ± 25 kg for Danish Friesian and Danish Jersey respectively. Faeces and herbage samples were analysed for alkanes to estimate herbage dry matter intake, dry matter digestibility (DMD) and botanical composition of intake. The weight gains at the time of herbage intake estimation in June (kg/day) were 1.142 ± 265 kg/day and 0.927 ± 168 kg/day for Danish Friesian and Danish Jersey respectively. Daily herbage intake (kg dry matter (DM)) estimated by alkanes C32 /C33 was 8.33 ± 0.97 and 6.28 ± 0.61 per day (P<0.001) and 3.15 ± 0.32 and 3.43 ± 0.30 per 100 kg liveweight (LW) (P<0.05) for Danish Friesian and Danish Jersey respectively. The botanical composition of the diet was the same for Danish Friesian and Danish Jersey with about half of the diet being grass leaves and the other half clover leaves. It is concluded that Danish Jersey steers have higher herbage intake per 100 kg LW than Danish Friesian steers of the same age, but herbage intake per kg metabolic LW is not different between the two breeds

Mast cell tumours and other skin neoplasia in Danish dogs - data from the Danish Veterinary Cancer Registry

<p>Abstract</p> <p>Background</p> <p>The Danish Veterinary Cancer Registry (DVCR) was established in May 2005 to gather information about neoplasms in the Danish dog and cat populations. Practitioners from more than 60 clinics throughout Denmark have submitted data on these species. The objectives of the current study were, with a special focus on mast cell tumours (MCT) to investigate the occurrence, gender distribution, biological behaviour, locations, types, the diagnostic method used and treatment of skin neoplasms in dogs based on information reported to the DVCR.</p> <p>Methods</p> <p>From May 15^th2005 through February 29^th2008, reports on a total of 1,768 canine cases of neoplasia in the skin, subcutis or adnexa were submitted.) Of these, 765 cases (43%) were confirmed by cytology or histopathology.</p> <p>Results</p> <p>The majority of dogs had a benign neoplasm (66%) while 21% were cases of malignant neoplasia. The most commonly encountered malignant neoplasms were MCT and soft tissue sarcomas and for benign neoplasms, lipomas and histiocytomas were the most common. The location of the neoplasms were primarily in the cutis, subcutis or in the perianal region. The occurrence, gender distribution, biological behaviour and location of canine skin neoplasias in Denmark were similar to earlier reports, although some national variations occurred. A correlation between grade of MCT and the proportion of cases treated surgically was observed.</p> <p>Conclusions</p> <p>Population based cancer registries like the DVCR are of importance in the collection of non-selected primary information about occurrence and distribution of neoplasms. The DVCR provides detailed information on cases of skin neoplasms in dogs and may serve as a platform for the study of sub-sets of neoplastic diseases (e.g. MCT) or subgroups of the canine population (e.g. a specific breed).</p

Oral malignant melanomas and other head and neck neoplasms in Danish dogs - data from the Danish Veterinary Cancer Registry

<p>Abstract</p> <p>Background</p> <p>Head and neck cancers (HNC) are relatively common and often very serious diseases in both dogs and humans. Neoplasms originating in the head and neck region are a heterogeneous group. HNC often has an unfavourable prognosis and the proximity of the tissue structures renders extirpation of tumours with sufficient margins almost incompatible with preservation of functionality. In humans oral malignant melanoma (OMM) is extremely rare, but represents a particular challenge since it is highly aggressive as is the canine counterpart, which thus may be of interest as a spontaneous animal model.</p> <p>Methods</p> <p>Canine cases entered in the Danish Veterinary Cancer Registry (DVCR) from May 15th 2005 through February 29th 2008 were included in this study. Fisher's exact test was used to compare proportions of HNC in dogs and humans as well as proportions of surgically treated cases of OMM and squamous cell carcinomas (SCC). Also the proportions of benign and malignant neoplasms of different locations in dogs were compared using Fisher's exact test.</p> <p>Results</p> <p>A total of 1768 cases of neoplasias (679 malignant, 826 benign, 263 unknown) were submitted. Of all neoplasias HNC accounted for 7.2% (n = 128). Of these, 64 (50%) were malignant and 44 (34%) benign. The most common types of malignant neoplasia were SCC (18; 28% of malignant), OMM (13; 20% of malignant), soft tissue sarcoma (11; 17% of malignant) and adenocarcinoma (5; 11% of malignant). The most common types of benign neoplasms were adenoma (7; 16% of benign), polyps (6; 14% of benign) and fibroma (5; 11% of benign).</p> <p>Conclusions</p> <p>In the current study, the proportion of neoplasia in the head and neck region in dogs in Denmark was similar to other canine studies and significantly more common than in humans with a large proportion of malignancies. Spontaneous HNC in dogs thus, may serve as a model for HNC in humans.</p> <p>Canine OMM is a spontaneous cancer in an outbred, immune-competent large mammal population and could be a clinical model for OMM in humans.</p

Motor Performance as Risk Factor for Lower Extremity Injuries in Children

Purpose: Physical activity related injuries in children constitute a costly public health matter. The influence of motor performance on injury risk is unclear. The purpose was to examine if motor performance was a risk factor of traumatic and overuse lower extremity injuries in a normal population of children. Methods: This study included 1244 participants from 8 to 14-years-old at baseline, all participating in "the Childhood Health, Activity and Motor Performance School Study Denmark". The follow-up period was up to 15 months. The motor performance tests were static balance, single leg hop for distance, core stability tests, vertical jump, shuttle run, and a cardiorespiratory fitness test. Lower extremity injuries were registered by clinicians by weekly questionnaires and classified according to the ICD-10 system. Results: Poor balance increased risk for traumatic injury in the foot region (IRR=1.09-1.15), and good performance in single leg hop for distance protected against traumatic knee injuries (IRR=0.66-0.68). Good performance in core stability tests and vertical jump increased the risk for traumatic injuries in the foot region (IRR=1.12-1.16). Poor balance increased the risk for overuse injuries in the foot region (IRR=1.65), as did good performance in core stability tests and shuttle run, especially for knee injuries (IRR=1.07-1.18). Conclusions: Poor balance (sway) performance was a consistent predictor of traumatic injuries, in particular for traumatic ankle injuries. Good motor performance (core stability, vertical jump, shuttle run) was positively associated with traumatic and overuse injuries, and negatively (single leg hop) associated with traumatic injuries, indicating different influence on injury risk. Previous injury was a confounder affecting the effect size and the significance. More studies are needed to consolidate the findings, to clarify the influence of different performance tests on different types of injuries and to examine the influence of behaviour in relation to injury ris

Water quality limits for Atlantic salmon (<i>Salmo salar</i> L.) exposed to short term reductions in pH and increased aluminum simulating episodes

International audienceAcidification has caused the loss or reduction of numerous Atlantic salmon (Salmo salar L.) populations on both sides of the North Atlantic. Acid deposition peaked in the 1980's and resulted in both chronically and episodically acidified rivers. At present, water quality is improving in all affected rivers due to reduced acid deposition. However, spring snow melt, heavy rainfall and sea salt episodes can still cause short term drops in pH and elevated concentrations of bioavailable aluminum. Technical malfunction in lime dozers will cause short termed episodic spates in the limed rivers. The current situation has prompted a need for dose-response relationships based on short term exposures of Atlantic salmon to assess the potential population effects of episodic acidification. Water quality guidelines for salmon have been lacking, despite a large number of experiments, all demonstrating dose-response relationships between water chemistry and fish health. We have summarized results from 347 short-term (+ and Al) and as Carlin-tagged smolt releases after preexposure to moderately acidic waters. The results from the various bioassays are compared to water quality limits proposed on basis of the relationship between water quality and population status/health in Norwegian rivers. The focus of this article is placed on chemical-biological interactions that can be drawn across experiments and exposure protocols. We propose dose-response relationships for acid neutralizing capacity (ANC), pH, cationic Al and gill accumulated Al, versus mortality in freshwater, effects on hypo-osmoregulatory capacity in seawater challenge tests and on smolt to adult survival in release experiments. The "no effect" dose depends on the life history stage tested and on the sensitivity of the biomarkers. Parr are more tolerant than smolt. Concentrations of Al that have no significant impact on freshwater life history stages can still have major population effects if they occur prior to smolt migration. While smolt can survive in freshwater for a prolonged period of time (>10 days) at an Al dose resulting in a gill Al concentration of up to 300 µg Alg?1 dw, a 3 day exposure resulting in a gill Al accumulation in the range of 25 to 60 µg Alg?1 dw reduces smolt to adult survival in a dose related manner by 20 to 50%. For smolt to adult survival, the biological significant response is delayed relative to the dose and occurs first after the fish enters the marine environment. In addition to exposure intensity and timing, exposure duration is important for the setting of critical limits

Entanglement-enhanced quantum rectification

Quantum mechanics dictates the band-structure of materials that is essential for functional electronic components. With increased miniaturization of devices it becomes possible to exploit the full potential of quantum mechanics through the principles of superpositions and entanglement. We propose a new class of quantum rectifiers that can leverage entanglement to dramatically increase performance by coupling two small spin chains through an effective double-slit interface. Simulations show that rectification is enhanced by several orders of magnitude even in small systems and should be realizable using several of the quantum technology platforms currently available.Comment: 5+15 pages, 3+6 figure