130 research outputs found

    Succeeding from Nature: The Non-Human Agency of Portuguese Cork

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    Non-human life has economic agency. It acts on the cultural values of products. Naturalness is an important property in the market and imbues vibrant materials with organic, healthy, traditional and other contingent properties. However, “natural” products can be succeeded in form and function by “synthetic” alternatives. Their value is further affected by non-humans. Our signal case explores Portuguese cork-bark, an agroforestry product grown in the montado, a biodiverse managed mosaic landscape of forestry and farming. The natural value of cork bottle stoppers is based on their effect on wine flavour. Oxygen permeable cork enables beneficial ageing to enhance flavour, whereas cork contaminated with taint degrades wine. Synthetic stoppers recreate the form and function of corks without being a vector for contamination. A succession from natural cork stoppers to reliable artificial polyethylene corks led to a decline in demand for cork bark and negative impacts on montado biodiversity. Yet here we demonstrate that such successions can be reversed as the affective properties of cork bark products became revalued with improvements in manufacturing, increasing concern for environmental sustainability and rising consumer demand for natural products. This leads us to explore further the dynamics between natural goods and synthetic replacements. We argue that rather than being two discrete domains of reality, natural and artificial products are both co-produced through assemblages of human and non-human action. Understanding succession between “natural” and “artificial” products enables new insights in to the geographies of non-human agency

    New Ce Heavy-Fermion System: CeCu

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    We have discovered a new heavy-fermion system, CeCu6, with a large susceptibility (=0.027 emu/mole G at 1.5 K) and a large, temperature-dependent specific heat below 10 K that is 840 mJ/mole K2 at 1.8 K and extrapolates to 1.6 J/mole K2 at T=0 in analogy with CeAl3. High-field specific-heat measurements agree almost perfectly with a narrow-band picture first proposed for UBe13. © 1984 The American Physical Society

    The α1-adrenergic receptors: diversity of signaling networks and regulation

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    The α1-adrenergic receptor (AR) subtypes (α1a, α1b, and α1d) mediate several physiological effects of epinephrineand norepinephrine. Despite several studies in recombinant systems and insightfrom genetically modified mice, our understanding of the physiological relevance and specificity of the α1-AR subtypes is still limited. Constitutive activity and receptor oligomerization have emerged as potential features regulating receptor function. Another recent paradigm is that βarrestins and G protein-coupled receptors themselves can act as scaffolds binding a variety of proteins and this can result in growing complexity of the receptor-mediated cellular effects. The aim of this review is to summarize our current knowledge on some recently identified functional paradigms and signaling networks that might help to elucidate the functional diversity of the α1-AR subtypes in various organs
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