872 research outputs found

    Trust Over Time in Exchange Relationships: Meta-Analysis and Theory

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    A common premise in prior research is that trust increases over time in relationships. Through a meta-analysis of 39 studies, we find that the bivariate correlation between trust and relationship duration (1) is on average positive and small, and (2) varies significantly across studies indicating the presence of unobserved moderators. We therefore build a theoretical framework to specify four different mechanismsā€”initial bias correction, change in relationship value, identification, and trust-based selectionā€”that may affect the development of trust. We then argue that the relative strength of these mechanisms should influence whether trust increases, remains constant, or decreases over time

    What next for preimplantation genetic screening? High mitotic chromosome instability rate provides the biological basis for the low success rate

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    Preimplantation genetic screening is being scrutinized, as recent randomized clinical trials failed to observe the expected significant increase in live birth rates following fluorescence in situ hybridization (FISH)-based screening. Although these randomized clinical trials are criticized on their design, skills or premature stop, it is generally believed that well-designed and well-executed randomized clinical trials would resolve the debate about the potential benefit of preimplantation genetic screening. Since FISH can analyze only a limited number of chromosomal loci, some of the embryos transferred might be diagnosed as ā€˜normalā€™ but in fact be aneuploid for one or more chromosomes not tested. Hence, genome-wide array comparative genome hybridization screening enabling aneuploidy detection of all chromosomes was thought to be a first step toward a better design. We recently showed array screening indeed enables accurate determination of the copy number state of all chromosomes in a single cell. Surprisingly, however, this genome-wide array screening revealed a much higher frequency and complexity of chromosomal aberrations in early embryos than anticipated, with imbalances in a staggering 90% of all embryos. The mitotic error rate in cleavage stage embryos was proven to be higher than the meiotic aneuploidy rate and as a consequence, the genome of a single blastomere is not representative for the genome of the other cells of the embryo. Hence, potentially viable embryos will be discarded upon screening a single blastomere. This observation provides a biological basis for the failure of the randomized clinical trials to increase baby-take-home rates using FISH on cleavage stage embroys

    Lagrangian transport by deep-water surface gravity wavepackets: effects of directional spreading and stratification

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    The Lagrangian mass transport by non-dissipating surface gravity wavepackets consists of the Stokes drift and the wave-induced return flow. We examine how directional spreading and density stratification affect this mass transport for an isolated non-dissipating wavepacket in deep water using a perturbation expansion. For an unstratified ocean, we show that the net displacement by the return flow is finite, negative, the same at all vertical levels and inversely proportional to the depth for spanwise-infinite packets representing unidirectional (two-dimensional) seas, but zero for spanwise-localised packets representing directionally spread seas (three-dimensional). We resolve this difference by demonstrating that a transition between two-dimensional-like (finite) and three-dimensional-like (zero) displacement occurs on a time scale inversely proportional to the degree of directional spreading. For a stratified ocean, we show that in two dimensions the net displacement profile by the return flow oscillates slowly with depth, with a wavelength dependent on the ratio of buoyancy frequency to the surface wave group velocity, and infinite displacements are predicted when the surface wavepacket resonantly excites internal waves. In three dimensions, the net displacement remains zero in the presence of stratification, but finite-time displacements may be appreciably altered

    Emissions from pre-Hispanic metallurgy in the South American atmosphere

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    This is the final version of the article. Available from Public Library of Science via the DOI in this record.Metallurgical activities have been undertaken in northern South America (NSA) for millennia. However, it is still unknown how far atmospheric emissions from these activities have been transported. Since the timing of metallurgical activities is currently estimated from scarce archaeological discoveries, the availability of reliable and continuous records to refine the timing of past metal deposition in South America is essential, as it provides an alternative to discontinuous archives, as well as evidence for global trace metal transport. We show in a peat record from Tierra del Fuego that anthropogenic metals likely have been emitted into the atmosphere and transported from NSA to southern South America (SSA) over the last 4200 yrs. These findings are supported by modern time back-trajectories from NSA to SSA. We further show that apparent anthropogenic Cu and Sb emissions predate any archaeological evidence for metallurgical activities. Lead and Sn were also emitted into the atmosphere as by-products of Inca and Spanish metallurgy, whereas local coal-gold rushes and the industrial revolution contributed to local contamination. We suggest that the onset of pre-Hispanic metallurgical activities is earlier than previously reported from archaeological records and that atmospheric emissions of metals were transported from NSA to SSA.This research is supported by a Young Researcher Grant of the Agence Nationale de la Recherche (ANR) to F. De Vleeschouwer (Project ANR-2011-JS56-006-01 ā€œPARADā€). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

    Emission of photon echoes in a strongly scattering medium

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    We observe the two- and three-pulse photon echo emission from a scattering powder, obtained by grinding a Pr3+^{3+}:Y2_2SiO5_5 rare earth doped single crystal. We show that the collective emission is coherently constructed over several grains. A well defined atomic coherence can therefore be created between randomly placed particles. Observation of photon echo on powders as opposed to bulk materials opens the way to faster material development. More generally, time-domain resonant four-wave mixing offers an attractive approach to investigate coherent propagation in scattering media
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