Indocyanine green elimination test in orthotopic liver recipients.

OBJECTIVE: To determine its predictive capability on graft quality and resultant clinical outcome, the indocyanine green (ICG) elimination test was performed by a spectrophotometric method and a noninvasive finger-piece method with 50 orthotopic liver transplantations. BACKGROUND: Early detection of poor-functioning hepatic grafts is one of the most important issues in liver transplantation, but no reliable methods exist. METHODS: The ICG test was performed after 50 orthotopic liver transplantations on postoperative days 1, 3, and 7. Indocyanine green elimination constants (K(ICG)) were measured by both a standard spectrophotometric analysis (K(ICG)-B) and by a finger-piece method (K(ICG)-F). The patients were followed for a minimum of 3 months after transplantation. Results of ICG tests were correlated with various clinical determinations. RESULTS: Twelve of the 50 grafts were lost within three months, of which 7 were related to graft failure. Multivariate analysis using the Cox proportional hazard model revealed that K(ICG) on postoperative day 1 was a better predictor of liver-related graft outcome than any of the conventional liver function tests. Furthermore, K(ICG) values showed significant correlation with the severity of preservation injury, longer intensive care unit (ICU) and hospital stay, prolonged liver dysfunction, and septic complications. Correlation of K(ICG) values by the spectrophotometric method with those by the finger-piece method was highly satisfactory in the grafts that had K(ICG)-B <0.15 min-1 (y = 0.868x -0.011, r = .955). CONCLUSION: The ICG elimination test, conducted spectrophotometrically or optically on the day after liver transplantation, is a reliable indicator of graft quality and subsequent graft outcome early after liver transplantation

Optical vernier technique for in-situ measurement of the length of long Fabry-Perot cavities

We propose a method for in-situ measurement of the length of kilometer size Fabry-Perot cavities in laser gravitational wave detectors. The method is based on the vernier, which occurs naturally when the laser incident on the cavity has a sideband. By changing the length of the cavity over several wavelengths we obtain a set of carrier resonances alternating with sideband resonances. From the measurement of the separation between the carrier and a sideband resonance we determine the length of the cavity. We apply the technique to the measurement of the length of a Fabry-Perot cavity in the Caltech 40m Interferometer and discuss the accuracy of the technique.Comment: LaTeX 2e, 12 pages, 4 figure

Data analysis of gravitational-wave signals from spinning neutron stars. II. Accuracy of estimation of parameters

We examine the accuracy of estimation of parameters of the gravitational-wave signals from spinning neutron stars that can be achieved from observations by Earth-based laser interferometers. We consider a model of the signal consisting of two narrowband components and including both phase and amplitude modulation. We calculate approximate values of the rms errors of the parameter estimators using the Fisher information matrix. We carry out extensive Monte Carlo simulations and obtain cumulative distribution functions of rms errors of astrophysically interesting parameters: amplitude of the signal, wobble angle, position of the source in the sky, frequency, and spindown coefficients. We consider both all-sky searches and directed searches. We also examine the possibility of determination of neutron star proper motion. We perform simulations for all laser-interferometric detectors that are currently under construction and for several possible lengths of the observation time and sizes of the parameter space. We find that observations of continuous gravitational-wave signals from neutron stars by laser-interferometric detectors will provide a very accurate information about their astrophysical properties. We derive several simplified models of the signal that can be used in the theoretical investigations of the data analysis schemes independently of the physical mechanisms generating the gravitational-wave signal.Comment: LaTeX, 34 pages, 15 figures, submitted to Phys. Rev.

Operational status of TAMA300 with the seismic attenuation system (SAS)

TAMA300 has been upgraded to improve the sensitivity at low frequencies after the last observation run in 2004. To avoid the noise caused by seismic activities, we installed a new seismic isolation system —- the TAMA seismic attenuation system (SAS). Four SAS towers for the test-mass mirrors were sequentially installed from 2005 to 2006. The recycled Fabry–Perot Michelson interferometer was successfully locked with the SAS. We confirmed the reduction of both length and angular fluctuations at frequencies higher than 1 Hz owing to the SAS

Optimal combination of signals from co-located gravitational wave interferometers for use in searches for a stochastic background

This article derives an optimal (i.e., unbiased, minimum variance) estimator for the pseudo-detector strain for a pair of co-located gravitational wave interferometers (such as the pair of LIGO interferometers at its Hanford Observatory), allowing for possible instrumental correlations between the two detectors. The technique is robust and does not involve any assumptions or approximations regarding the relative strength of gravitational wave signals in the detector pair with respect to other sources of correlated instrumental or environmental noise. An expression is given for the effective power spectral density of the combined noise in the pseudo-detector. This can then be introduced into the standard optimal Wiener filter used to cross-correlate detector data streams in order to obtain an optimal estimate of the stochastic gravitational wave background. In addition, a dual to the optimal estimate of strain is derived. This dual is constructed to contain no gravitational wave signature and can thus be used as on "off-source" measurement to test algorithms used in the "on-source" observation.Comment: 14 pages, 4 figures, submitted to Physical Review D Resubmitted after editing paper in response to referee comments. Removed appendices A, B and edited text accordingly. Improved legibility of figures. Corrected several references. Corrected reference to science run number (S1 vs. S2) in text and figure caption

No association between fruit or vegetable consumption and the risk of colorectal cancer in Japan

In a pooled analysis of two prospective studies with 88 658 Japanese men and women, fruit and vegetable consumptions, were not associated with a lower risk of colorectal cancer (705 cases); multivariate relative risk (95% confidence interval) for the highest vs the lowest quartile of intake being 0.92 (0.70–1.19) and 1.00 (0.79–1.27), respectively

Quantum statistical properties of the radiation field in a cavity with a movable mirror

A quantum system composed of a cavity radiation field interacting with a movable mirror is considered and quantum statistical properties of the field are studied. Such a system can serve in principle as an idealized meter for detection of a weak classical force coupled to the mirror which is modelled by a quantum harmonic oscillator. It is shown that the standard quantum limit on the measurement of the mirror position arises naturally from the properties of the system during its dynamical evolution. However, the force detection sensitivity of the system falls short of the corresponding standard quantum limit. We also study the effect of the nonlinear interaction between the moving mirror and the radiation pressure on the quadrature fluctuations of the initially coherent cavity field.Comment: REVTeX, 9 pages, 5 figures. More info on http://www.ligo.caltech.edu/~cbrif/science.htm

Gravitational Waves from Chaotic Dynamical System

To investigate how chaos affects gravitational waves, we study the gravitational waves from a spinning test particle moving around a Kerr black hole, which is a typical chaotic system. To compare the result with those in non-chaotic dynamical system, we also analyze a spinless test particle, which orbit can be complicated in the Kerr back ground although the system is integrable. We estimate the emitted gravitational waves by the multipole expansion of a gravitational field. We find a striking difference in the energy spectra of the gravitational waves. The spectrum for a chaotic orbit of a spinning particle, contains various frequencies, while some characteristic frequencies appear in the case of a spinless particle.Comment: 8 pages, 13 figures. submitted to PR

Coherent Bayesian inference on compact binary inspirals using a network of interferometric gravitational wave detectors

Presented in this paper is a Markov chain Monte Carlo (MCMC) routine for conducting coherent parameter estimation for interferometric gravitational wave observations of an inspiral of binary compact objects using data from multiple detectors. The MCMC technique uses data from several interferometers and infers all nine of the parameters (ignoring spin) associated with the binary system, including the distance to the source, the masses, and the location on the sky. The Metropolis-algorithm utilises advanced MCMC techniques, such as importance resampling and parallel tempering. The data is compared with time-domain inspiral templates that are 2.5 post-Newtonian (PN) in phase and 2.0 PN in amplitude. Our routine could be implemented as part of an inspiral detection pipeline for a world wide network of detectors. Examples are given for simulated signals and data as seen by the LIGO and Virgo detectors operating at their design sensitivity.Comment: 10 pages, 4 figure

Testing the performance of a blind burst statistic

In this work we estimate the performance of a method for the detection of burst events in the data produced by interferometric gravitational wave detectors. We compute the receiver operating characteristics in the specific case of a simulated noise having the spectral density expected for Virgo, using test signals taken from a library of possible waveforms emitted during the collapse of the core of Type II Supernovae.Comment: 8 pages, 6 figures, Talk given at the GWDAW2002 worksho