Effects of long rarefied plasma on fast electron generation for FIREX-I targets

Long-scale preformed plasmas are generated inside the cone by the pre-pulse of the heating laser in the cone-guided fast ignition scheme and it is found that coupling efficiency from the heating laser to fast electrons especially suitable for core heating is drastically reduced by the preformed plasmas. To mitigate this serious problem, an extremely thin film is suggested to cover the entrance of the cone. This method, however, introduces long rarefied plasmas around the entrance of the cone and the main pulse must propagate through these plasmas. Therefore, fast electron characteristics produced by the main pulse could be affected, and effects of long rarefied plasmas on fast electron generation are investigated. It is found that the electron beam intensity becomes larger than that without the rarefied plasma, but the energy coupling rate from the heating laser to the core decreases due to lack of appropriate electrons for core heating. To achieve less than 10% degradation of the core electron temperature, the thin film must be expanded by irradiation of the pre-pulse so that the length and the density of rarefied plasmas become less than 500 ?m and one-tenth of the critical density. A thickness of the thin film can be determined by these criteria and the intensity of the pre-pulse

Delay analysis for CBR traffic under static-priority scheduling

We examine the delay performance of packets from constant-bit-rate (CBR) traffic whose delay is affected by non-real-time traffic. The delay performance is analyzed by solving the nD/D/1 queue with vacations. We obtain an exact and closed form solution, hence obviating the need of any approximations or numerical Laplace inversions. We then provide various numerical results for low-bit-rate transmission links, in which packets can experience large delay. From our quantitative evaluation, we conclude that there exists an optimum packet size for a given delay bound. In extremely slow links, such as modem links, transmission control protocol (TCP) packets should be segmented to reduce the CBR delay. We therefore investigate the delay impact of TCP packet sizes as wel

A CE assay for the detection of agonist-stimulated adenylyl cyclase activity

A CE assay was developed for the detection of adenylyl cyclase (AC) activity stimulated at the AC and G protein-coupled receptor (GPCR) level. In the assay, cell membranes overexpressing GPCR and/or AC were incubated with modulators and substrate ATP to produce cAMP in a dose-dependent manner. In both the CE-UV and a radiochemical assay, the addition of forskolin (FSK) resulted in a two- to three-fold maximum increase in AC activity with EC 50 s of 4.2 14± 140.7 and 2.4 14± 140.7 14ΜM, respectively, demonstrating that similar results were obtained by both assays. GPCR activation was also detected using cell membranes overexpressing AC and the Β 2 -adrenergic receptor (Β 2 AR) fused to the stimulatory G protein. Terbutaline (Β 2 AR agonist) increased the basal rate of cAMP formation 1.7 14± 140.1-fold resulting in an EC 50 of 62 14± 1410 14nM. The assay's ability to detect antagonists is demonstrated by the expected right-shifted EC 50 of terbutaline by the Β 2 AR antagonist propranolol. The CE-UV assay offers advantages over the traditional radioactivity assay in terms of safety and labor.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/56060/1/1913_ftp.pd