471 research outputs found

    A new finite element formulation of three-dimensional beam theory based on interpolation of curvature

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    A new finite element formulation of the *kinematically exact finite-strain beam theory* is presented. The finite element formulation employs the generalized virtual work in which the main role is played by the pseudo-curvature vector. The solution of the governing equations is found by using a combined Galerkin-collocation algorith

    Bounds on R-parity Violation from Resonant Slepton Production at the LHC

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    We consider the ATLAS and CMS searches for dijet resonances, as well as the ATLAS search for like-sign dimuon pairs at the LHC with 7 TeV center of mass energy. We interpret their exclusions in terms of bounds on the supersymmetric R-parity violating parameter space. For this we focus on resonant slepton production followed by the corresponding decay.Comment: 17 pages, 11 figures, 3 table

    Resurrecting light stops after the 125 GeV Higgs in the baryon number violating CMSSM

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    In order to accommodate the observed Higgs boson mass in the CMSSM, the stops must either be very heavy or the mixing in the stop sector must be very large. Lower stop masses, possibly more accessible at the LHC, still give the correct Higgs mass only if the trilinear stop mixing parameter At|A_t| is in the multi-TeV range. Recently it has been shown that such large stop mixing leads to an unstable electroweak vacuum which spontaneously breaks charge or colour. In this work we therefore go beyond the CMSSM and investigate the effects of including baryon number violating operators λUˉDˉDˉ\lambda'' \bar{\bf U} \bar{\bf D}\bar{\bf D} on the stop and Higgs sectors. We find that for λO(0.3)\lambda'' \simeq {\mathcal{O}}(0.3) light stop masses as low as 220 GeV are consistent with the observed Higgs mass as well as flavour constraints while allowing for a stable vacuum. The light stop in this scenario is often the lightest supersymmetric particle. We furthermore discuss the importance of the one-loop corrections involving R-parity violating couplings for a valid prediction of the light stop masses.Comment: 26 pages, 9 figures; v2: slightly extended discussion about bounds from flavour observables; matches published versio

    Discovery Potential of Selectron or Smuon as the Lightest Supersymmetric Particle at the LHC

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    We investigate the LHC discovery potential of R-parity violating supersymmetric models with a right-handed selectron or smuon as the lightest supersymmetric particle (LSP). These LSPs arise naturally in R-parity violating minimal supergravity models. We classify the hadron collider signatures and perform for the first time within these models a detailed signal over background analysis. We develop an inclusive three-lepton search and give prospects for a discovery at a center-of-mass energy of 7 TeV as well as 14 TeV. There are extensive parameter regions which the LHC can already test with 7 TeV and an integrated luminosity of 1 inverse femtobarn. We also propose a method for the mass reconstruction of the supersymmetric particles within our models at 14 TeV.Comment: 33 pages, 24 figures; preprint number added, layout correcte

    The Role of Dysregulated miRNAs in the Pathogenesis, Diagnosis and Treatment of Age-Related Macular Degeneration

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    Age-related macular degeneration (AMD) is an eye disease causing damage to the macular region of the retina where most of the photoreceptors responsible for central visual acuity are located. MicroRNAs (miRNAs) are small single-stranded non-coding RNA molecules that negatively regulate genes by silent post-transcriptional gene expressions. Previous studies have shown that changes in specific miRNAs are involved in the pathogenesis of eye diseases, including AMD. Altered expressions of miRNAs are related to disturbances of regulating oxidative stress, inflammation, angiogenesis, apoptosis and phagocytosis, which are known factors in the pathogenesis of AMD. Moreover, dysregulation of miRNA is involved in drusen formation. Thus, miRNAs may be used as potential molecular biomarkers for the disease and, furthermore, tailoring therapeutics to particular disturbances in miRNAs may, in the future, offer hope to prevent irreversible vision loss. In this review, we clarify the current state of knowledge about the influence of miRNA on the pathogenesis, diagnosis and treatment of AMD. Our study material consisted of publications, which were found in PubMed, Google Scholar and Embase databases using "Age-related macular degeneration", "miRNA", "AMD biomarkers", "miRNA therapeutics" and "AMD pathogenesis" as keywords. Paper search was limited to articles published from 2011 to date. In the section "Retinal, circulating and vitreous body miRNAs found in human studies", we limited the search to studies with patients published in 2016-2021

    Application ofyo1k immunoglobulin in prophylaxis of diarrhea in piglets

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    The yolk immunoglobulin (IgY) preparate was added to the fodder of piglets to establish its prophylactic role in the periods of highest incidence of diarrhea. IgY was added in the proportion of 0,5g (Dl), lg (02) or 2g (03) /kg of the fodder, (control group without IgY) and given to suckling piglets (5-21 days old, in summary 873 from 81 sows at four groups, experiment 1.), or to piglets during first 30 days after weaning (15 piglets in each of the groups, experiment 2.). Experiment 1.: diarrhea occurred in 6.72% of suckling control piglets whereas no diarrhea was found in Dl group, in 0.92% of 02, and in 3.21% of 03 group. The incidence of other diseases was also higher in control than in experimental groups. The percent of reared piglets was significantly higher in experimental ( 89.17-91.98%, than in the control (82.21 %) groups

    Report on the 2013 Rapid Assessment Survey of Marine Species at New England Bays and Harbors

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    Introduced species (i.e., non-native species that have become established in a new location) have increasingly been recognized as a concern as they have become more prevalent in marine and terrestrial environments (Mooney and Cleland 2001; Simberloff et al. 2005). The ability of introduced species to alter population, community, and ecosystem structure and function, as well as cause significant economic damage is well documented (Carlton 1989, 1996b, 2000; Cohen and Carlton 1995; Cohen et al. 1995; Elton 1958; Meinesz et al. 1993; Occhipinti-Ambrogi and Sheppard 2007; Pimentel et al. 2005; Thresher 2000). The annual economic costs incurred from managing the approximately 50,000 introduced species in the United States alone are estimated to be over $120 billion (Pimentel et al. 2005). Having a monitoring network in place to track new introductions and distributional changes of introduced species is critical for effective management, as these efforts may be more successful when species are detected before they have the chance to become established. A rapid assessment survey is one such method for early detection of introduced species. With rapid assessment surveys, a team of taxonomic experts record and monitor marine species–providing a baseline inventory of native, introduced, and cryptogenic (i.e., unknown origin) species (as defined by Carlton 1996a)–and document range expansions of previously identified species. Since 2000, five rapid assessment surveys have been conducted in New England. These surveys focus on recording species at marinas, which often are in close proximity to transportation vectors (i.e., recreational boats). Species are collected from floating docks and piers because these structures are accessible regardless of the tidal cycle. Another reason for sampling floating docks and other floating structures is that marine introduced species are often found to be more prevalent on artificial surfaces than natural surfaces (Glasby and Connell 2001; Paulay et al. 2002). The primary objectives of these surveys are to: (1) identify native, introduced, and cryptogenic marine species, (2) expand on data collected in past surveys, (3) assess the introduction status and range extensions of documented introduced species, and (4) detect new introductions. This report presents the introduced, cryptogenic, and native species recorded during the 2013 survey
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