800 research outputs found
Partial-Wave Analysis of the Centrally Produced {\pi}+{\pi}- System in pp Reactions at COMPASS
COMPASS is a fixed-target experiment at CERN SPS which investigates the
structure and spectroscopy of hadrons. During nine weeks in 2008 and 2009, a
190 GeV/c proton beam impinging on a liquid hydrogen target was used in order
to study the production of exotic mesons and glueball candidates at central
rapidities. As no bias on the production mechanism was introduced by the
trigger system, the contribution from diffractive dissociation of the beam
proton poses a challenge. We select a centrally produced sample by kinematic
cuts and introduce a model to describe the data in terms of partial waves.
Preliminary fits are presented, which are consistent with results from previous
experiments. Particular attention is paid to the ambiguities in the amplitude
analysis of the two-pseudoscalar final state.Comment: Sixth International Conference on Quarks and Nuclear Physics, April
16-20, 2012, Ecole Polytechnique, Palaiseau, Paris PoS (QNP2012) 09
Localization versus function of Rab3 proteins - Evidence for a common regulatory role in controlling fusion
Rab3A, Rab3B, Rab3C, and Rab3D constitute a family of GTP- binding proteins that are implicated in regulated exocytosis. Various localizations and distinct functions have been proposed for different and occasionally even for the same Rab3 protein. This is exemplified by studies demonstrating that deletion of Rab3A in knock-out mice results in dysregulation of the final stages of exocytosis, whereas overexpression of Rab3A in neuroendocrine cells causes nearly complete inhibition of Ca2+- triggered exocytosis. We have now examined the properties of all Rab3 proteins in the same assays, with the long-term goal of identifying a common conceptual framework for their functions. Using quantitative immunoblotting, we found that all four Rab3 proteins were expressed in brain and endocrine tissues, although at widely different levels. Rab3A, Rab3B, and Rab3C co-localized to synaptic and secretory vesicles consistent with potential redundancy, whereas Rab3D was expressed at high levels only in the endocrine pituitary (where it was more abundant than Rab3A, Rab3B, and Rab3C combined), in exocrine glands, and in adipose tissue. In transfected PC12 cells, all four Rab3 proteins strongly inhibited Ca2+-triggered exocytosis. Except for a mutation that fixes Rab3 into a permanently GDP-bound state, all Rab3 mutations tested had no effect on this inhibition, including a mutation in the calmodulin-binding site that was described as inactivating (Coppola, T., Perret-Menoud, V., Luthi, S., Farnsworth, C. C., Glomset, J. A., and Regazzi, R. (1999) EMBO J. 18, 5885- 5891).:Unexpectedly, overexpression of wild type Rab3A and permanently GTP-bound mutant Rab3A in PC12 cells caused a loss of secretory vesicles and an increase in constitutive, Ca2+- independent exocytosis that correlated with the inhibition of regulated Ca2+-triggered exocytosis. Our data indicate that overexpression of Rab3 in PC12 cells impairs the normal control of the final step in exocytosis, thereby converting the regulated secretory pathway into a constitutive pathway. These results offer an hypothesis that reconciles Rab3 transfection and knockout studies by suggesting that Rab3 functions as a gatekeeper of a late stage in exocytosis
Empiric Models of the Earth's Free Core Nutation
Free core nutation (FCN) is the main factor that limits the accuracy of the
modeling of the motion of Earth's rotational axis in the celestial coordinate
system. Several FCN models have been proposed. A comparative analysis is made
of the known models including the model proposed by the author. The use of the
FCN model is shown to substantially increase the accuracy of the modeling of
Earth's rotation. Furthermore, the FCN component extracted from the observed
motion of Earth's rotational axis is an important source for the study of the
shape and rotation of the Earth's core. A comparison of different FCN models
has shown that the proposed model is better than other models if used to
extract the geophysical signal (the amplitude and phase of FCN) from
observational data.Comment: 8 pages, 3 figures; minor update of the journal published versio
Angle Dependent Magnetoresistance of the Layered Organic Superconductor \kappa-(ET)2Cu(NCS)2: Simulation and Experiment
The angle-dependences of the magnetoresistance of two different isotopic
substitutions (deuterated and undeuterated) of the layered organic
superconductor \kappa-(ET)2Cu(NCS)2 are presented. The angle dependent
magnetoresistance oscillations (AMRO) arising from the quasi-one-dimensional
(Q1D) and quasi-two-dimensional (Q2D) Fermi surfaces in this material are often
confused. By using the Boltzman transport equation extensive simulations of the
AMRO are made that reveal the subtle differences between the different species
of oscillation. No significant differences are observed in the electronic
parameters derived from quantum oscillations and AMRO for the two isotopic
substitutions. The interlayer transfer integrals are determined for both
isotopic substitutions and a slight difference is observed which may account
for the negative isotope effect previously reported [1]. The success of the
semi-classical simulations suggests that non-Fermi liquid effects are not
required to explain the interlayer-transport in this system.Comment: 15 pages, 16 figure
In vivo T cell depleted unrelated allogeneic stem cell transplantation with a reduced intensity regimen in patients with advanced hematologic malignancies
Anisotropic charge dynamics in the quantum spin-liquid candidate -(BEDT-TTF)Cu(CN)
We have in detail characterized the anisotropic charge response of the dimer
Mott insulator -(BEDT-TTF)\-Cu(CN) by dc conductivity, Hall
effect and dielectric spectroscopy. At room temperature the Hall coefficient is
positive and close to the value expected from stoichiometry; the temperature
behavior follows the dc resistivity . Within the planes the dc
conductivity is well described by variable-range hopping in two dimensions;
this model, however, fails for the out-of-plane direction. An unusually broad
in-plane dielectric relaxation is detected below about 60 K; it slows down much
faster than the dc conductivity following an Arrhenius law. At around 17 K we
can identify a pronounced dielectric anomaly concomitantly with anomalous
features in the mean relaxation time and spectral broadening. The out-of-plane
relaxation, on the other hand, shows a much weaker dielectric anomaly; it
closely follows the temperature behavior of the respective dc resistivity. At
lower temperatures, the dielectric constant becomes smaller both within and
perpendicular to the planes; also the relaxation levels off. The observed
behavior bears features of relaxor-like ferroelectricity. Because
heterogeneities impede its long-range development, only a weak tunneling-like
dynamics persists at low temperatures. We suggest that the random potential and
domain structure gradually emerge due to the coupling to the anion network.Comment: 14 pages, 13 figure
Dissipation in the superconducting state of kappa-(BEDT-TTF)2Cu(NCS)2
We have studied the interlayer resistivity of the prototypical
quasi-two-dimensional organic superconductor -(BEDT-TTF)Cu(NCS)
as a function of temperature, current and magnetic field, within the
superconducting state. We find a region of non-zero resistivity whose
properties are strongly dependent on magnetic field and current density. There
is a crossover to non-Ohmic conduction below a temperature that coincides with
the 2D vortex solid -- vortex liquid transition. We interpret the behaviour in
terms of a model of current- and thermally-driven phase slips caused by the
diffusive motion of the pancake vortices which are weakly-coupled in adjacent
layers, giving rise to a finite interlayer resistance.Comment: Four pages, three figure
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