2,668 research outputs found
Hardware Realization of a General Purpose FFT Processor in a Distributed Processing Configuration
An efficient hardware implementation of a 1024-point sequential FFT processor is described. The processor has been configured in a distributed processing system with an INTEL 8086 microprocessor. In case of real signals, it performs a 1024-point transform of two real signals, simultaneously within the same period and subsequently does spectral separation 2.6 msec. Its general purpose capability and the case of interfacing it with standard mini/micro computers are highlighted with a specific illustrations using the INTEL 8086 microprocessor
Modifying the photodetachment near a metal surface by a weak electric field
We show the photodetachment cross sections of H near a metal surface can be
modified using a weak static electric field. The modification is possible
because the oscillatory part of the cross section near a metal surface is
directly connected with the transit-time and the action of the
detached-electron closed-orbit which can be changed systematically by varying
the static electric field strength. Photodetachment cross sections for various
photon energies and electric field values are calculated and displayed.Comment: 16 pages, 7 figure
Combined exposure to cigarette smoke and nontypeable Haemophilus influenzae drives development of a COPD phenotype in mice
Abstract
Background
Cigarette smoke (CS) is the major etiologic factor of chronic obstructive pulmonary disease (COPD). CS-exposed mice develop emphysema and mild pulmonary inflammation but no airway obstruction, which is also a prominent feature of COPD. Therefore, CS may interact with other factors, particularly respiratory infections, in the pathogenesis of airway remodeling in COPD.
Methods
C57BL/6 mice were exposed to CS for 2Â h a day, 5Â days a week for 8Â weeks. Mice were also exposed to heat-killed non-typeable H. influenzae (HK-NTHi) on days 7 and 21. One day after the last exposure to CS, mice were sacrificed and lung inflammation and mechanics, emphysematous changes, and goblet cell metaplasia were assessed. Mice exposed to CS or HK-NTHi alone or room air served as controls. To determine the susceptibility to viral infections, we also challenged these mice with rhinovirus (RV).
Results
Unlike mice exposed to CS or HK-NTHi alone, animals exposed to CS/HK-NTHi developed emphysema, lung inflammation and goblet cell metaplasia in both large and small airways. CS/HK-NTHi-exposed mice also expressed increased levels of mucin genes and cytokines compared to mice in other groups. CS/HK-NTHi-exposed mice infected with RV demonstrated increased viral persistence, sustained neutrophilia, and further increments in mucin gene and chemokine expression compared to other groups.
Conclusions
These findings indicate that in addition to CS, bacteria may also contribute to development of COPD, particularly changes in airways. Mice exposed to CS/HK-NTHi are also more susceptible to subsequent viral infection than mice exposed to either CS or HK-NTHi alone.http://deepblue.lib.umich.edu/bitstream/2027.42/109487/1/12931_2013_Article_1465.pd
Optimal Control for Generating Quantum Gates in Open Dissipative Systems
Optimal control methods for implementing quantum modules with least amount of
relaxative loss are devised to give best approximations to unitary gates under
relaxation. The potential gain by optimal control using relaxation parameters
against time-optimal control is explored and exemplified in numerical and in
algebraic terms: it is the method of choice to govern quantum systems within
subspaces of weak relaxation whenever the drift Hamiltonian would otherwise
drive the system through fast decaying modes. In a standard model system
generalising decoherence-free subspaces to more realistic scenarios,
openGRAPE-derived controls realise a CNOT with fidelities beyond 95% instead of
at most 15% for a standard Trotter expansion. As additional benefit it requires
control fields orders of magnitude lower than the bang-bang decouplings in the
latter.Comment: largely expanded version, superseedes v1: 10 pages, 5 figure
Examining adherence to activity monitoring devices to improve physical activity in adults with cardiovascular disease: A systematic review
Background
Activity monitoring devices are currently being used to facilitate and monitor physical activity. No prior review has examined adherence to the use of activity monitoring devices amongst adults with cardiovascular disease.
Methods
Literature from June 2012 to October 2017 was evaluated to examine the extent of adherence to any activity monitoring device used to collect objective physical activity data. Randomized control trials comparing usual care against the use of an activity monitoring device, in a community intervention for adults from any cardiovascular diagnostic group, were included. A systematic search of databases and clinical trials registers was conducted using Joanna Briggs Institute methodology.
Results
Of 10 eligible studies, two studies reported pedometer use and eight accelerometer use. Six studies addressed the primary outcome. Mean adherence was 59.1% (range 39.6% to 85.7%) at last follow-up. Studies lacked equal representation by gender (28.6% female) and age (range 42 to 82 years).
Conclusion
This review indicates that current research on activity monitoring devices may be overstated due to the variability in adherence. Results showed that physical activity tracking in women and in young adults have been understudied
Combined exposure to cigarette smoke and nontypeable Haemophilus influenzae drives development of a COPD phenotype in mice
Abstract
Background
Cigarette smoke (CS) is the major etiologic factor of chronic obstructive pulmonary disease (COPD). CS-exposed mice develop emphysema and mild pulmonary inflammation but no airway obstruction, which is also a prominent feature of COPD. Therefore, CS may interact with other factors, particularly respiratory infections, in the pathogenesis of airway remodeling in COPD.
Methods
C57BL/6 mice were exposed to CS for 2Â h a day, 5Â days a week for 8Â weeks. Mice were also exposed to heat-killed non-typeable H. influenzae (HK-NTHi) on days 7 and 21. One day after the last exposure to CS, mice were sacrificed and lung inflammation and mechanics, emphysematous changes, and goblet cell metaplasia were assessed. Mice exposed to CS or HK-NTHi alone or room air served as controls. To determine the susceptibility to viral infections, we also challenged these mice with rhinovirus (RV).
Results
Unlike mice exposed to CS or HK-NTHi alone, animals exposed to CS/HK-NTHi developed emphysema, lung inflammation and goblet cell metaplasia in both large and small airways. CS/HK-NTHi-exposed mice also expressed increased levels of mucin genes and cytokines compared to mice in other groups. CS/HK-NTHi-exposed mice infected with RV demonstrated increased viral persistence, sustained neutrophilia, and further increments in mucin gene and chemokine expression compared to other groups.
Conclusions
These findings indicate that in addition to CS, bacteria may also contribute to development of COPD, particularly changes in airways. Mice exposed to CS/HK-NTHi are also more susceptible to subsequent viral infection than mice exposed to either CS or HK-NTHi alone.http://deepblue.lib.umich.edu/bitstream/2027.42/134587/1/12931_2013_Article_1465.pd
Biochemical characterization and 16s rRNA sequencing of different bacteria from textile dye effluents
Environmental pollution has been identified as a major problem in the modern world. Dyeing effluents have become a vital source of water pollution. Release of coloured textile effluents is undesirable in the aquatic environment as they reduce light penetration, thereby affecting aquatic life and limits utilization of the water media. In Tirupur, the textile factories discharge millions of litres of untreated effluents into the drains that eventually empty into river, Noyyal. The release of coloured compound into water bodies is undesirable not only because of their impact on photosynthesis of aquatic plants but also due to the carcinogenic nature of these dyes and their breakdown products. The ability of bacterial strains isolated from the dye effluent of textile mill sites. Morphological and biochemical characterization was done to identify isolates and was found to be Pseudomonas spp, Bacillus spp and Serattia spp. The isolated strains were finally identified by 16S rRNA sequence analysis. Bacteria are generally identified by 16S rRNA sequencing. The rRNA is the most conserved (least variable) gene in all cells. They were identified as Pseudomonas aeruginosa, Bacillus amyloliquefaciens and Serattia liquefaciens. The sequences were deposited in GENBANK. The accession numbers were KU041528, KU041530 and KU041531 respectively. The identification was conformed by 16S rRNA sequencing.
Keywords: Textile Dye Effluents, Bacteria, 16S rRNA, NCBI
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Bullying behaviours and other conduct problems: longitudinal investigation of their independent associations with risk factors and later outcomes
Purpose Bullying behaviours and other conduct problems often co-occur. However, we do not yet know whether bullying
behaviours are associated with early factors and later poor outcomes independently of conduct problems. While there are
difering, specifc interventions for bullying behaviours and for conduct problems, it is unclear if such specifcity is justifed
given parallels between both behaviours.
Methods We used prospective data from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative sample of 2232 children. Mothers and teachers reported on children’s bullying behaviours and conduct problems
at ages 7 and 10. We collected measures of risk factors, including temperament and family factors, when children were age
5. We assessed behavioural, emotional, educational and social problems when participants reached the ages of 12 and 18.
Results Bullying behaviours and conduct problems co-occurred in childhood. Our fndings indicated that bullying behaviours
and other conduct problems were independently associated with the same risk factors. Furthermore, they were associated with
the same poor outcomes at both ages 12 and 18. Despite this, bullying behaviours were uniquely associated with behavioural,
emotional, educational and social problems at age 18.
Conclusions Our fndings suggest that anti-bullying programmes and interventions aimed at reducing conduct problems
could beneft from greater integration. Furthermore, our study highlights the mental health problems children who bully
may face in later years and the need to consider those in intervention plans
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