Strandings of cetaceans and sea turtles in the Alboran Sea and Strait of Gibraltar: a long-term glimpse at the north coast (Spain) and the south coast (Morocco)

., 2011. Strandings of cetaceans and sea turtles in the Alboran Sea and Strait of Gibraltar: a long-time glimpse of the north coast (Spain) and the south coast (Morocco). Animal Biodiversity and Conservation, 34.1: 151-163. Abstract Strandings of cetaceans and sea turtles in the Alboran Sea and Strait of Gibraltar: a long-term glimpse at the north coast (Spain) and the south coast (Morocco) .-A total of 13 species of cetaceans and three species of marine turtles were found in this study. Data were collected by eight independent and self-regulated stranding networks, providing information about 1,198 marine mammal (10 odontocetii, three mysticetii and one phocidae) and 574 sea turtle stranding events between 1991 and 2008. Trends in the strandings were analysed in relation to species composition and abundance, and their geographic and seasonal distribution. The most abundant species recorded were the striped dolphin and the loggerhead turtle. Some of the strandings, such as the humpback whale, harbour porpoise, hooded seal and olive ridley turtle, were considered 'rare' because their distribution did not match the pattern of the study. When the north and south coasts in the study area were compared, pilot whales stranded more frequently in the north, while delphinid species stranded more in the south coast, and loggerhead turtles stranded more frequently in the north while leatherback turtles stranded more in south coast. Key words: Strandings, South-western Mediterranean, Distribution, Marine turtle, Cetacean, Conservation. Resumen Varamientos de cetáceos y tortugas marinas en el mar de Alborán y el Estrecho de Gibraltar: un vistazo a largo plazo de la costa norte (España) y la costa sur (Marruecos) .-En este estudio se registraron un total de 13 especies de cetáceos y tres especies de tortugas marinas, proviniendo los datos de redes de voluntarios que prestan asistencia en los varamientos. Se recogió información de 1.198 mamiferos marinos (10 odontocetos, tres misticetos y un fócido) y 574 tortugas marinas entre los años 1991 y 2008. Se analizaron las tendencias de los varamientos en relación a la composición de especies, su abundancia y su distribución geográfica y estacional. Las especies más comunes fueron el delfín común y la tortuga boba. Algunos de los varamientos, como la ballena jorobada, la marsopa común, la foca de casco o la tortuga olivácea, pueden considerarse "anómalos" puesto que su distribución se escapa a los patrones del estudio. Comparando la costa norte del área de estudio con la sur, los calderones y tortugas bobas vararon con mayor frecuencia en la costa norte, mientras que las especies de delfines y las tortugas laúd vararon con mayor frecuencia en la costa sur

Strandings of cetaceans and sea turtles in the Alboran Sea and Strait of Gibraltar: a long–time glimpse of the north coast (Spain) and the south coast (Morocco)

A total of 13 species of cetaceans and three species of marine turtles were found in this study. Data were collected by eight independent and self-regulated stranding networks, providing information about 1,198 marine mammal (10 odontocetii, three mysticetii and one phocidae) and 574 sea turtle stranding events between 1991 and 2008. Trends in the strandings were analysed in relation to species composition and abundance, and their geographic and seasonal distribution. The most abundant species recorded were the striped dolphin and the loggerhead turtle. Some of the strandings, such as the humpback whale, harbour porpoise, hooded seal and olive ridley turtle, were considered ‘rare’ because their distribution did not match the pattern of the study. When the north and south coasts in the study area were compared, pilot whales stranded more frequently in the north, while delphinid species stranded more in the south coast, and loggerhead turtles stranded more frequently in the north while leatherback turtles stranded more in south coast

Genetic and phenotypic characterisation of HIV-associated aggressive B-cell non-Hodgkin lymphomas, which do not occur specifically in this population : diagnostic and prognostic implications

Altres ajuts: acord transformatiu CRUE-CSICAltres ajuts: Gilead Sciences S.L. (GLD19/00121); Josep Carreras International Foundation; "la Caixa" FoundationThe frequency of aggressive subtypes of B-cell non-Hodgkin lymphoma (B-NHL), such as high-grade B-cell lymphomas (HGBL) with MYC and BCL2 and/or BCL6 rearrangement (HGBL-DH/TH) or Burkitt-like lymphoma (BL) with 11q aberration, is not well known in the HIV setting. We aimed to characterise HIV-associated aggressive B-NHL according to the 2017 WHO criteria, and to identify genotypic and phenotypic features with prognostic impact. Seventy-five HIV-associated aggressive B-NHL were studied by immunohistochemistry (CD10, BCL2, BCL6, MUM1, MYC, and CD30), EBV-encoded RNAs (EBERs), and fluorescence in situ hybridisation (FISH) to evaluate the status of the MYC, BCL2, and BCL6 genes and chromosome 11q. The 2017 WHO classification criteria and the Hans algorithm, for the cell-of-origin classification of diffuse large B-cell lymphomas (DLBCL), were applied. In DLBCL cases, the frequencies of MYC and BCL6 rearrangements (14.9 and 27.7%, respectively) were similar to those described in HIV-negative patients, but BCL2 rearrangements were infrequent (4.3%). MYC expression was identified in 23.4% of DLBCL cases, and coexpression of MYC and BCL2 in 13.0%, which was associated with a worse prognosis. As for BL cases, the expression of MUM1 (30.4%) conferred a worse prognosis. Finally, the prevalence of HGBL-DH/TH and BL-like with 11q aberration are reported in the HIV setting. The phenotypic and genotypic characteristics of HIV-associated aggressive B-NHL are similar to those of the general population, except for the low frequency of BCL2 rearrangements in DLBCL. MYC and BCL2 coexpression in DLBCL, and MUM-1 expression in BL, have a negative prognostic impact on HIV-infected individuals