554 research outputs found

    3D Numerical Simulation of Eddy Current Testing of a Block with a Crack

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    There are many approaches to 3D eddy current analysis. Typical methods for the eddy current analysis are the A-ø method and the T-ω method. Both methods require variables in space as well as in a conductor. We have already proposed the T method [1, 2, 3], where a magnetic scalar potential ω is not included and we do not need variables in space. But the method has a disadvantage that a large core memory is needed due to a dense matrix

    Role of the imprinted allele of the Cdkn1c gene in mouse neocortical development

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    Imprinted genes are expressed from only one allele in a parent of origin–specific manner. The cyclin-dependent kinase inhibitor p57^{kip2} is encoded by an imprinted gene Cdkn1c, with the paternal allele being silenced. The possible expression and function of the paternal allele of Cdkn1c have remained little studied, however. We now show that the paternal allele of the Cdkn1c gene is expressed at a low level in the developing mouse neocortex. Surprisingly, the central nervous system-specific conditional deletion of the paternal allele (pat cKO) at the Cdkn1c locus resulted in a marked reduction in brain size. Furthermore, pat cKO gradually reduced the number of neural stem-progenitor cells (NPCs) during neocortical development, and thus reduced the number of upper-layer neurons, which were derived from late-stage NPCs. Our results thus show that the paternal allele of the Cdkn1c locus plays a key role in maintenance of NPCs during neocortical development

    Political Commitment and Sense of Social Responsibility among Social Entrepreneurs in Davao City, Philippines

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    Social entrepreneurs can play a game-changing role in local and national development by introducing social innovation. Strongly committed and mission- driven, they employ entrepreneurial schemes to organize and manage resources through financially sound and economically sustainable entities in order to create social value. This study aimed to determine the levels of political commitment and sense of social responsibility among social entrepreneurs of small and medium-sized social enterprises in Davao City. Using the non-experimental descriptive correlation method to gather survey inputs from 47 respondents, the researchers found that the respondents exhibited high levels of political commitment and sense of social responsibility. Furthermore, a significant relationship existed between political commitment and sense of social responsibility. When analyzed according to sex, no significant difference was observed in the level of political commitment. However, a significant difference appeared when analyzed according to type of business venture. No significant difference was ever observed in the level of sense of social responsibility in both variables
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