Research Update on Extreme-Mass-Ratio Inspirals

The inspirals of stellar-mass mass compact objects into massive black holes in the centres of galaxies are one of the most important sources of gravitational radiation for space-based detectors like LISA or eLISA. These extreme-mass-ratio inspirals (EMRIs) will enable an ambitious research program with implications for astrophysics, cosmology, and fundamental physics. This article is a summary of the talks delivered at the plenary session on EMRIs at the 10th International LISA Symposium. It contains research updates on the following topics: astrophysics of EMRIs; EMRI science potential; and EMRI modeling.Comment: 17 pages, no figures. Proceedings of the LISA Symposium X, to be published at the Journal of Physic

Test of the weak cosmic censorship conjecture with a charged scalar field and dyonic Kerr-Newman black holes

A thought experiment considered recently in the literature, in which it is investigated whether a dyonic Kerr-Newman black hole can be destroyed by overcharging or overspinning it past extremality by a massive complex scalar test field, is revisited. Another derivation of the result that this is not possible, i.e. the weak cosmic censorship is not violated in this thought experiment, is given. The derivation is based on conservation laws, on a null energy condition, and on specific properties of the metric and the electromagnetic field of dyonic Kerr-Newman black holes. The metric is kept fixed, whereas the dynamics of the electromagnetic field is taken into account. A detailed knowledge of the solutions of the equations of motion is not needed. The approximation in which the electromagnetic field is fixed is also considered, and a derivation for this case is also given. In addition, an older version of the thought experiment, in which a pointlike test particle is used, is revisited. The same result, namely the non-violation of the cosmic censorship, is rederived in a way which is simpler than in earlier works.Comment: 18 pages, LaTe

Carbon Monoxide Induced Erythroid Differentiation of K562 Cells Mimics the Central Macrophage Milieu in Erythroblastic Islands

Growing evidence supports the role of erythroblastic islands (EI) as microenvironmental niches within bone marrow (BM), where cell-cell attachments are suggested as crucial for erythroid maturation. The inducible form of the enzyme heme oxygenase, HO-1, which conducts heme degradation, is absent in erythroblasts where hemoglobin (Hb) is synthesized. Yet, the central macrophage, which retains high HO-1 activity, might be suitable to take over degradation of extra, harmful, Hb heme. Of these enzymatic products, only the hydrophobic gas molecule - CO can transfer from the macrophage to surrounding erythroblasts directly via their tightly attached membranes in the terminal differentiation stage

Self-force: Computational Strategies

Building on substantial foundational progress in understanding the effect of a small body's self-field on its own motion, the past 15 years has seen the emergence of several strategies for explicitly computing self-field corrections to the equations of motion of a small, point-like charge. These approaches broadly fall into three categories: (i) mode-sum regularization, (ii) effective source approaches and (iii) worldline convolution methods. This paper reviews the various approaches and gives details of how each one is implemented in practice, highlighting some of the key features in each case.Comment: Synchronized with final published version. Review to appear in "Equations of Motion in Relativistic Gravity", published as part of the Springer "Fundamental Theories of Physics" series. D. Puetzfeld et al. (eds.), Equations of Motion in Relativistic Gravity, Fundamental Theories of Physics 179, Springer, 201