A Degenerate Bose-Fermi Mixture of Metastable Atoms

We report the observation of simultaneous quantum degeneracy in a dilute gaseous Bose-Fermi mixture of metastable atoms. Sympathetic cooling of helium-3 (fermion) by helium-4 (boson), both in the lowest triplet state, allows us to produce ensembles containing more than 10^6 atoms of each isotope at temperatures below 1 micro-Kelvin, and achieve a fermionic degeneracy parameter of T/Tf=0.45. Due to their high internal energy, the detection of individual metastable atoms with sub-nanosecond time resolution is possible, permitting the study of bosonic and fermionic quantum gases with unprecedented precision. This may lead to metastable helium becoming the mainstay of quantum atom optics.Comment: 4 pages, 3 figures submitted to PR

A Large Atom Number Metastable Helium Bose-Einstein Condensate

We have produced a Bose-Einstein condensate of metastable helium (4He*) containing over 1.5x10^7 atoms, which is a factor of 25 higher than previously achieved. The improved starting conditions for evaporative cooling are obtained by applying one-dimensional Doppler cooling inside a magnetic trap. The same technique is successfully used to cool the spin-polarized fermionic isotope (3He*), for which thermalizing collisions are highly suppressed. Our detection techniques include absorption imaging, time-of-flight measurements on a microchannel plate detector and ion counting to monitor the formation and decay of the condensate.Comment: 4 pages, 3 figures (changed content

Producing and Detecting Correlated atoms

We discuss experiments to produce and detect atom correlations in a degenerate or nearly degenerate gas of neutral atoms. First we treat the atomic analog of the celebrated Hanbury Brown Twiss experiment, in which atom correlations result simply from interference effects without any atom interactions.We have performed this experiment for both bosons and fermions. Next we show how atom interactions produce correlated atoms using the atomic analog of spontaneous four-wavemixing. Finally, we briefly mention experiments on a one dimensional gas on an atom chip in which correlation effects due to both interference and interactions have been observed.Comment: to appear in conference proceedings "Atomic Physics 20

Dietary Acrylamide Intake and the Risk of Lymphatic Malignancies: The Netherlands Cohort Study on Diet and Cancer

BACKGROUND: Acrylamide, a probable human carcinogen, is present in many everyday foods. Since the finding of its presence in foods in 2002, epidemiological studies have found some suggestive associations between dietary acrylamide exposure and the risk of various cancers. The aim of this prospective study is to investigate for the first time the association between dietary acrylamide intake and the risk of several histological subtypes of lymphatic malignancies. METHODS: The Netherlands Cohort Study on diet and cancer includes 120,852 men and women followed-up since September 1986. The number of person years at risk was estimated by using a random sample of participants from the total cohort that was chosen at baseline (n =5,000). Acrylamide intake was estimated from a food frequency questionnaire combined with acrylamide data for Dutch foods. Hazard ratios (HRs) were calculated for acrylamide intake as a continuous variable as well as in categories (quintiles and tertiles), for men and women separately and for never-smokers, using multivariable-adjusted Cox proportional hazards models. RESULTS: After 16.3 years of follow-up, 1,233 microscopically confirmed cases of lymphatic malignancies were available for multivariable-adjusted analysis. For multiple myeloma and follicular lymphoma, HRs for men were 1.14 (95% CI: 1.01, 1.27) and 1.28 (95% CI: 1.03, 1.61) per 10 µg acrylamide/day increment, respectively. For never-smoking men, the HR for multiple myeloma was 1.98 (95% CI: 1.38, 2.85). No associations were observed for women. CONCLUSION: We found indications that acrylamide may increase the risk of multiple myeloma and follicular lymphoma in men. This is the first epidemiological study to investigate the association between dietary acrylamide intake and the risk of lymphatic malignancies, and more research into these observed associations is warranted

Camparison of the Hanbury Brown-Twiss effect for bosons and fermions

Fifty years ago, Hanbury Brown and Twiss (HBT) discovered photon bunching in light emitted by a chaotic source, highlighting the importance of two-photon correlations and stimulating the development of modern quantum optics . The quantum interpretation of bunching relies upon the constructive interference between amplitudes involving two indistinguishable photons, and its additive character is intimately linked to the Bose nature of photons. Advances in atom cooling and detection have led to the observation and full characterisation of the atomic analogue of the HBT effect with bosonic atoms. By contrast, fermions should reveal an antibunching effect, i.e., a tendency to avoid each other. Antibunching of fermions is associated with destructive two-particle interference and is related to the Pauli principle forbidding more than one identical fermion to occupy the same quantum state. Here we report an experimental comparison of the fermion and the boson HBT effects realised in the same apparatus with two different isotopes of helium, 3He (a fermion) and 4He (a boson). Ordinary attractive or repulsive interactions between atoms are negligible, and the contrasting bunching and antibunching behaviours can be fully attributed to the different quantum statistics. Our result shows how atom-atom correlation measurements can be used not only for revealing details in the spatial density, or momentum correlations in an atomic ensemble, but also to directly observe phase effects linked to the quantum statistics in a many body system. It may thus find applications to study more exotic situations >.Comment: Nature 445, 402 (2007). V2 includes the supplementary informatio

Effects of beta-alanine supplementation on brain homocarnosine/carnosine signal and cognitive function: an exploratory study

Objectives: Two independent studies were conducted to examine the effects of 28 d of beta-alanine supplementation at 6.4 g d-1 on brain homocarnosine/carnosine signal in omnivores and vegetarians (Study 1) and on cognitive function before and after exercise in trained cyclists (Study 2). Methods: In Study 1, seven healthy vegetarians (3 women and 4 men) and seven age- and sex-matched omnivores undertook a brain 1H-MRS exam at baseline and after beta-alanine supplementation. In study 2, nineteen trained male cyclists completed four 20-Km cycling time trials (two pre supplementation and two post supplementation), with a battery of cognitive function tests (Stroop test, Sternberg paradigm, Rapid Visual Information Processing task) being performed before and after exercise on each occasion. Results: In Study 1, there were no within-group effects of beta-alanine supplementation on brain homocarnosine/carnosine signal in either vegetarians (p = 0.99) or omnivores (p = 0.27); nor was there any effect when data from both groups were pooled (p = 0.19). Similarly, there was no group by time interaction for brain homocarnosine/carnosine signal (p = 0.27). In study 2, exercise improved cognitive function across all tests (P0.05) of beta-alanine supplementation on response times or accuracy for the Stroop test, Sternberg paradigm or RVIP task at rest or after exercise. Conclusion: 28 d of beta-alanine supplementation at 6.4g d-1 appeared not to influence brain homocarnosine/ carnosine signal in either omnivores or vegetarians; nor did it influence cognitive function before or after exercise in trained cyclists