Three-dimensional carrier-dynamics simulation of terahertz emission from photoconductive switches

A semi-classical Monte Carlo model for studying three-dimensional carrier dynamics in photoconductive switches is presented. The model was used to simulate the process of photoexcitation in GaAs-based photoconductive antennas illuminated with pulses typical of mode-locked Ti:Sapphire lasers. We analyzed the power and frequency bandwidth of THz radiation emitted from these devices as a function of bias voltage, pump pulse duration and pump pulse location. We show that the mechanisms limiting the THz power emitted from photoconductive switches fall into two regimes: when illuminated with short duration (<40 fs) laser pulses the energy distribution of the Gaussian pulses constrains the emitted power, while for long (>40 fs) pulses, screening is the primary power-limiting mechanism. A discussion of the dynamics of bias field screening in the gap region is presented. The emitted terahertz power was found to be enhanced when the exciting laser pulse was in close proximity to the anode of the photoconductive emitter, in agreement with experimental results. We show that this enhancement arises from the electric field distribution within the emitter combined with a difference in the mobilities of electrons and holes.Comment: 7 pages, 7 figure

Correlations of Globular Cluster Properties: Their Interpretations and Uses

Correlations among the independently measured physical properties of globular clusters (GCs) can provide powerful tests for theoretical models and new insights into their dynamics, formation, and evolution. We review briefly some of the previous work, and present preliminary results from a comparative study of GC correlations in the Local Group galaxies. The results so far indicate that these diverse GC systems follow the same fundamental correlations, suggesting a commonality of formative and evolutionary processes which produce them.Comment: An invited review, to appear in "New Horizons in Globular Cluster Astronomy", eds. G. Piotto, G. Meylan, S.G. Djorgovski, and M. Riello, ASPCS, in press (2003). Latex file, 8 pages, 5 eps figures, style files include

Endotracheal intubation to reduce aspiration events in acutely comatose patients: a systematic review

Background: It is customary to believe that a patient with a Glasgow Coma Scale (GCS) score less than or equal to 8 should be intubated to avoid aspiration. We conducted a systematic review to establish if patients with GCS 64 8 for trauma or non-traumatic emergencies and treated in the acute care setting (e.g., Emergency Department or Pre-hospital environment) should be intubated to avoid aspiration or aspiration pneumonia/pneumonitis, and consequently, reduce mortality. Methods: We searched six databases, Pubmed, Embase, Scopus, SpringerLink, Cochrane Library, and Ovid Emcare, from April 15th to October 14th, 2020, for studies involving low GCS score patients of whom the risk of aspiration and related complications was assessed. Results: Thirteen studies were included in the final analysis (7 on non-traumatic population, 4 on trauma population, 1 pediatric and 1 adult mixed case studies). For the non-traumatic cases, two prospective studies and one retrospective study found no difference in aspiration risk between intubated and non-intubated patients. Two retrospective studies reported a reduction in the risk of aspiration in the intubated patient group. For traumatic cases, the study that considered the risk of aspiration did not show any differences between the two groups. A study on adult mixed cases found no difference in the incidence of aspiration among intubated and non-intubated patients. A study on pediatric patients found increased mortality for intubated versus non-intubated non-traumatic patients with a low GCS score. Conclusion: Whether intubation results in a reduction in the incidence of aspiration events and whether these are more frequent in patients with low GCS scores are not yet established. The paucity of evidence on this topic makes clinical trials justifiable and necessary. Trial registration: Prospero registration number: CRD42020136987

Treatment of esophageal achalasia in children: Today and tomorrow

Esophageal achalasia (EA) is a rare esophageal motility disorder in children. Laparoscopic Heller myotomy (LHM) represents the treatment of choice in young patients. Peroral endoscopic myotomy (POEM) is becoming an alternative to LHM. The aim of this study is to evaluate the effectiveness, safety, and outcomes of POEM vs LHM in treatment of children with EA. Data of pediatric patients with EA, who underwent LHM and POEM from February 2009 to December 2013 in two centers, were collected. Eighteen patients (9 male, mean age: 11.6 years; range: 2-17 years) were included. Nine patients (6 male, mean age: 10.7 years; range: 2-16 years) underwent LHM, and the other 9 (3 males, mean age: 12.2 years; range: 6-17 years) underwent POEM procedure. Mean operation time was shorter in POEM group compared with LHM group (62/149 minutes). Myotomy was longer in POEM group than in LHM group (11/7 cm). One major complication occurred after LHM (esophageal perforation). No clinical and manometric differences were observed between LHM and POEM in follow-up. The incidence of iatrogenic gastroesophageal reflux disease was low (1 patient in both groups). Results of a midterm follow-up show that LHM and POEM are safe and effective treatments also in children. Besides, POEM is a mini-invasive technique with an inferior execution timing compared to LHM. A skilled endoscopic team is mandatory to perform this procedur

The Kinematics and Metallicity of the M31 Globular Cluster System

With the ultimate aim of distinguishing between various models describing the formation of galaxy halos (e.g. radial or multi-phase collapse, random mergers), we have completed a spectroscopic study of the globular cluster system of M31. We present the results of deep, intermediate-resolution, fibre-optic spectroscopy of several hundred of the M31 globular clusters using the Wide Field Fibre Optic Spectrograph (WYFFOS) at the William Herschel Telescope in La Palma, Canary Islands. These observations have yielded precise radial velocities (+/-12 km/s) and metallicities (+/-0.26 dex) for over 200 members of the M31 globular cluster population out to a radius of 1.5 degrees from the galaxy center. Many of these clusters have no previous published radial velocity or [Fe/H] estimates, and the remainder typically represent significant improvements over earlier determinations. We present analyses of the spatial, kinematic and metal abundance properties of the M31 globular clusters. We find that the abundance distribution of the cluster system is consistent with a bimodal distribution with peaks at [Fe/H] = -1.4 and -0.5. The metal-rich clusters demonstrate a centrally concentrated spatial distribution with a high rotation amplitude, although this population does not appear significantly flattened and is consistent with a bulge population. The metal-poor clusters tend to be less spatially concentrated and are also found to have a strong rotation signature.Comment: 33 pages, 20 figure

Another Non-segregated Blue Straggler Population in a Globular Cluster: the Case of NGC 2419

We have used a combination of ACS-HST high-resolution and wide-field SUBARU data in order to study the Blue Straggler Star (BSS) population over the entire extension of the remote Galactic globular cluster NGC 2419. The BSS population presented here is among the largest ever observed in any stellar system, with more than 230 BSS in the brightest portion of the sequence. The radial distribution of the selected BSS is essentially the same as that of the other cluster stars. In this sense the BSS radial distribution is similar to that of omega Centauri and unlike that of all Galactic globular clusters studied to date, which have highly centrally segregated distributions and, in most cases, a pronounced upturn in the external regions. As in the case of omega Centauri, this evidence indicates that NGC 2419 is not yet relaxed even in the central regions. This observational fact is in agreement with estimated half-mass relaxation time, which is of the order of the cluster age.Comment: in press in the Ap

An HST/WFPC2 survey of bright young clusters in M31. I. VdB0, a massive star cluster seen at t ≃ 25 Myr

Aims. We introduce our imaging survey of possible young massive globular clusters in M31 performed with the Wide Field and Planetary Camera 2 (WFPC2) on the Hubble Space Telescope (HST). We obtained shallow (to B ~ 25) photometry of individual stars in 20 candidate clusters. We present here details of the data reduction pipeline that is being applied to all the survey data and describe its application to the brightest among our targets, van den Bergh 0 (VdB0), taken as a test case. Methods. Point spread function fitting photometry of individual stars was obtained for all the WFPC2 images of VdB0 and the completeness of the final samples was estimated using an extensive set of artificial stars experiments. The reddening, the age and the metallicity of the cluster were estimated by comparing the observed color magnitude diagram (CMD) with theoretical isochrones. Structural parameters were obtained from model-fitting to the intensity profiles measured within circular apertures on the WFPC2 images. Results. Under the most conservative assumptions, the stellar mass of VdB0 is M> 2.4 x 10^4 M_☉ , but our best estimates lie in the range ≃4-9 x 10^4 M_☉. The CMD of VdB0 is best reproduced by models having solar metallicity and age ≃25 Myr. Ages less than ≃12 Myr and greater than ≃60 Myr are clearly ruled out by the available data. The cluster has a remarkable number of red super giants (≳18) and a CMD very similar to Large Magellanic Cloud clusters usually classified as young globulars such as NGC 1850, for example. Conclusions. VdB0 is significantly brighter (≳1 mag) than Galactic open clusters of similar age. Its present-day mass and half-light radius ((r_h = 7.4 pc) are more typical of faint globular clusters than of open clusters. However, given its position within the disk of M31, it is expected to be destroyed by dynamical effects, in particular by encounters with giant molecular clouds, within the next ~4 Gyr