Three-Body Dynamics with Gravitational Wave Emission

We present numerical three-body experiments that include the effects of gravitational radiation reaction by using equations of motion that include the 2.5-order post-Newtonian force terms, which are the leading order terms of energy loss from gravitational waves. We simulate binary-single interactions and show that close approach cross sections for three 1 solar mass objects are unchanged from the purely Newtonian dynamics except for close approaches smaller than 1.0e-5 times the initial semimajor axis of the binary. We also present cross sections for mergers resulting from gravitational radiation during three-body encounters for a range of binary semimajor axes and mass ratios including those of interest for intermediate-mass black holes (IMBHs). Building on previous work, we simulate sequences of high-mass-ratio three-body encounters that include the effects of gravitational radiation. The simulations show that the binaries merge with extremely high eccentricity such that when the gravitational waves are detectable by LISA, most of the binaries will have eccentricities e > 0.9 though all will have circularized by the time they are detectable by LIGO. We also investigate the implications for the formation and growth of IMBHs and find that the inclusion of gravitational waves during the encounter results in roughly half as many black holes ejected from the host cluster for each black hole accreted onto the growing IMBH.Comment: 34 pages, 14 figures, minor corrections to match version accepted by Ap

Lineage tracing of Foxd1-expressing embryonic progenitors to assess the role of divergent embryonic lineages on adult dermal fibroblast function

Recent studies have highlighted the functional diversity of dermal fibroblast populations in health and disease, with part of this diversity linked to fibroblast lineage and embryonic origin. Fibroblasts derived from foxd1-expressing progenitors contribute to the myofibroblast populations present in lung and kidney fibrosis in mice but have not been investigated in the context of dermal wound repair. Using a Cre/Lox system to genetically track populations derived from foxd1-expressing progenitors, lineage-positive fibroblasts were identified as a subset of the dermal fibroblast population. During development, lineage-positive cells were most abundant within the dorsal embryonic tissues, contributing to the developing dermal fibroblast population, and remaining in this niche into adulthood. In adult mice, assessment of fibrosis-related gene expression in lineage-positive and lineage-negative populations isolated from wounded and unwounded dorsal skin was performed, identifying an enrichment of transcripts associated with matrix synthesis and remodeling in the lineage-positive populations. Using a novel excisional wound model, ventral skin healed with a greatly reduced frequency of foxd1 lineage-positive cells. This work supports that the embryonic origin of fibroblasts is an important predictor of fibroblast function, but also highlights that within disparate regions, fibroblasts of different lineages likely undergo convergent differentiation contributing to phenotypic similarities

Tidal Evolution of the Earth–Moon System with a High Initial Obliquity

A giant impact origin for the Moon is generally accepted, but many aspects of lunar formation remain poorly understood and debated. \'Cuk et al. (2016) proposed that an impact that left the Earth-Moon system with high obliquity and angular momentum could explain the Moon's orbital inclination and isotopic similarity to Earth. In this scenario, instability during the Laplace Plane transition, when the Moon's orbit transitions from the gravitational influence of Earth's figure to that of the Sun, would both lower the system's angular momentum to its present-day value and generate the Moon's orbital inclination. Recently, Tian and Wisdom (2020) discovered new dynamical constraints on the Laplace Plane transition and concluded that the Earth-Moon system could not have evolved from an initial state with high obliquity. Here we demonstrate that the Earth-Moon system with an initially high obliquity can evolve into the present state, and we identify a spin-orbit secular resonance as a key dynamical mechanism in the later stages of the Laplace Plane transition. Some of the simulations by Tian and Wisdom (2020) did not encounter this late secular resonance, as their model suppressed obliquity tides and the resulting inclination damping. Our results demonstrate that a giant impact that left Earth with high angular momentum and high obliquity ($\theta > 61^{\circ}$) is a promising scenario for explaining many properties of the Earth-Moon system, including its angular momentum and obliquity, the geochemistry of Earth and the Moon, and the lunar inclination.Comment: Accepted for the Planetary Science Journa

Sesquinary Catastrophe For Close-In Moons with Dynamically Excited Orbits

We identify a new mechanism that can lead to the destruction of small, close-in planetary satellites. If a small moon close to the planet has a sizable eccentricity and inclination, its ejecta that escape to planetocentric orbit would often re-impact with much higher velocity due to the satellite's and the fragment's orbits precessing out of alignment. If the impacts of returning ejecta result in net erosion, a runaway process can occur which may end in disruption of the satellite, and we term this process ``sesquinary catastrophe''. We expect the moon to re-accrete, but on an orbit with significantly lower eccentricity and inclination. We find that the large majority of small close-in moons in the Solar System, have orbits that are immune to sesquinary catastrophe. The exceptions include a number of resonant moonlets of Saturn for which resonances may affect the velocities of re-impact of their own debris. Additionally, we find that Neptune's moon Naiad (and to a lesser degree, Jupiter's Thebe) must have substantial internal strength, in line with prior estimates based on Roche limit stability. We also find that sesquinary instability puts important constraints on the plausible past orbits of Phobos and Deimos or their progenitors.Comment: Accepted for Ap

Periostin as a Multifunctional Modulator of the Wound Healing Response

During tissue healing, dynamic and temporal alterations occur in the structure and composition of the extracellular matrix (ECM) that are required for effective repair to occur. Matricellular proteins (MPs) are a group of diverse non-structural ECM components, which bind cell surface receptors mediating interactions between the cell and its microenviroment, effectively regulating adhesion, migration, proliferation, signaling and cell phenotype. Periostin (Postn), a pro-fibrogenic secreted glycoprotein, was defined as a MP based on its expression pattern and regulatory roles during development, healing and in disease processes. Postn consists of a typical signal sequence, an EMI domain responsible for binding to fibronectin, four tandem fasciclin-like domains that are responsible for integrin binding and a C-terminal region where multiple splice variants originate. This review will focus specifically on the role of Postn in wound healing and remodeling, an area of intense research in the last 10 years particularly related to skin healing as well as in myocardium post infarction. Postn interacts with cells through various integrin pairs and is an essential downstream effector of TGF-β superfamily signaling. As will be discussed, across different tissues, Postn is associated with pro-fibrogenic process, specifically, the transition of fibroblasts to myofibroblasts, collagen fibrillogenesis and ECM synthesis. Although the complexity of Postn as a modulator of cell behavior in tissue healing is only beginning to be elucidated, its expression is clearly a defining event in moving wound healing through the proliferative and remodeling phases

Herschel Observations of Cataclysmic Variables

We have used the PACS instrument on the Herschel Space Observatory to observe eight cataclysmic variables at 70 and 160 μm. Of these eight objects, only AM Her was detected. We have combined the Herschel results with ground-based, Spitzer, and WISE observations to construct spectral energy distributions for all of the targets. For the two dwarf novae in the sample, SS Cyg and U Gem, we find that their infrared luminosities are completely dominated by their secondary stars. For the two highly magnetic "polars" in our survey, AM Her and EF Eri, we find that their mid-infrared excesses, previously attributed to circumbinary dust emission, can be fully explained by cyclotron emission. The WISE light curves for both sources show large, orbitally modulated variations that are identically phased to their near-IR light curves. We propose that significant emission from the lowest cyclotron harmonics (n ≤ 3) is present in EF Eri and AM Her. Previously, such emission would have been presumed to be optically thick, and not provide significant orbitally modulated flux. This suggests that the accretion onto polars is more complicated than assumed in the simple models developed for these two sources. We develop a model for the near-/mid-IR light curves for WZ Sge with an L2 donor star that shows that the ellipsoidal variations from its secondary star are detected. We conclude that none of the targets surveyed have dusty circumbinary disks

Implications of the PSR 1257+12 Planetary System for Isolated Millisecond Pulsars

The first extrasolar planets were discovered in 1992 around the millisecond pulsar PSR 1257+12. We show that recent developments in the study of accretion onto magnetized stars, plus the existence of the innermost, moon-sized planet in the PSR 1257+12 system, suggest that the pulsar was born with approximately its current rotation frequency and magnetic moment. If so, this has important implications for the formation and evolution of neutron star magnetic fields as well as for the formation of planets around pulsars. In particular, it suggests that some and perhaps all isolated millisecond pulsars may have been born with high spin rates and low magnetic fields instead of having been recycled by accretion.Comment: 17 pages including one figure, uses aaspp4, accepted by Ap