A new magnetic white dwarf : PG2329+267

We have discovered that the white dwarf PG 2329+267 is magnetic, and assuming a centered dipole structure, has a dipole magnetic field strength of approximately 2.3MG. This makes it one of only approximately 4% of isolated white dwarfs with a detectable magnetic field. Linear Zeeman splitting as well as quadratic Zeeman shifts are evident in the hydrogen Balmer sequence and circular spectropolarimetry reveals 10% circular polarisation in the two displaced sigma components of Halpha. We suggest from comparison with spectra of white dwarfs of known mass that PG 2329+267 is more massive than typical isolated white dwarfs, in agreement with the hypothesis that magnetic white dwarfs evolve from magnetic chemically peculiar Ap and Bp type main sequence stars.Comment: 5 pages, with 2 encapsulated postscipts figures include

Behavior-Based Outlier Detection for Network Access Control Systems

Network Access Control (NAC) systems manage the access of new devices into enterprise networks to prevent unauthorised devices from attacking network services. The main difficulty with this approach is that NAC cannot detect abnormal behaviour of devices connected to an enterprise network. These abnormal devices can be detected using outlier detection techniques. Existing outlier detection techniques focus on specific application domains such as fraud, event or system health monitoring. In this paper, we review attacks on Bring Your Own Device (BYOD) enterprise networks as well as existing clustering-based outlier detection algorithms along with their limitations. Importantly, existing techniques can detect outliers, but cannot detect where or which device is causing the abnormal behaviour. We develop a novel behaviour-based outlier detection technique which detects abnormal behaviour according to a device type profile. Based on data analysis with K-means clustering, we build device type profiles using Clustering-based Multivariate Gaussian Outlier Score (CMGOS) and filter out abnormal devices from the device type profile. The experimental results show the applicability of our approach as we can obtain a device type profile for five dell-netbooks, three iPads, two iPhone 3G, two iPhones 4G and Nokia Phones and detect outlying devices within the device type profile

Random Projections For Large-Scale Regression

Fitting linear regression models can be computationally very expensive in large-scale data analysis tasks if the sample size and the number of variables are very large. Random projections are extensively used as a dimension reduction tool in machine learning and statistics. We discuss the applications of random projections in linear regression problems, developed to decrease computational costs, and give an overview of the theoretical guarantees of the generalization error. It can be shown that the combination of random projections with least squares regression leads to similar recovery as ridge regression and principal component regression. We also discuss possible improvements when averaging over multiple random projections, an approach that lends itself easily to parallel implementation.Comment: 13 pages, 3 Figure

A Self-Occulting Accretion Disk in the SW Sex Star DW UMa

We present the ultraviolet spectrum of the SW Sex star and nova-like variable DW UMa in an optical low state, as observed with the Space Telescope Imaging Spectrograph on board the Hubble Space Telescope (HST). The data are well described by a synthetic white dwarf (WD) spectrum with T_eff = 46,000 +/- 1000 K, log g = 7.60 +/- 0.15, v*sin(i) = 370 +/- 100 km/s and Z/Z_solar = 0.47 +/- 0.15. For this combination of T_eff and log g, WD models predict M_WD = 0.48 +/- 0.06 M_solar and R_WD = (1.27 +/- 0.18) * 10^9 cm. Combining the radius estimate with the normalization of the spectral fit, we obtain a distance estimate of d = 830 +/-150 pc. During our observations, DW UMa was approximately 3 magnitudes fainter in V than in the high state. A comparison of our low-state HST spectrum to a high-state spectrum obtained with the International Ultraviolet Explorer shows that the former is much bluer and has a higher continuum level shortward of 1450 A. Since DW UMa is an eclipsing system, this suggests that an optically thick accretion disk rim blocks our view of the WD primary in the high state. If self-occulting accretion disks are common among the SW Sex stars, we can account for (i) the preference for high-inclination systems within the class and (ii) their V-shaped continuum eclipses. Moreover, even though the emission lines produced by a self-obscured disk are generally still double-peaked, they are weaker and narrower than those produced by an unobscured disk. This may allow a secondary line emission mechanism to dominate and produce the single-peaked, optical lines that are a distinguishing characteristic of the SW Sex stars.Comment: 9 pages, including 2 figures; accepted for publication in Astrophysical Journal Letters; New version matches version in press (footnote added to discussion section; figures now use color

Searching for nova shells around cataclysmic variables

We present the results of a search for nova shells around 101 cataclysmic variables (CVs), using Halpha images taken with the 4.2-m William Herschel Telescope (WHT) and the 2.5-m Isaac Newton Telescope Photometric Halpha Survey of the Northern Galactic Plane (IPHAS). Both telescopes are located on La Palma. We concentrated our WHT search on nova-like variables, whilst our IPHAS search covered all CVs in the IPHAS footprint. We found one shell out of the 24 nova-like variables we examined. The newly discovered shell is around V1315 Aql and has a radius of approx.2.5 arcmin, indicative of a nova eruption approximately 120 years ago. This result is consistent with the idea that the high mass-transfer rate exhibited by nova-like variables is due to enhanced irradiation of the secondary by the hot white dwarf following a recent nova eruption. The implications of our observations for the lifetime of the nova-like variable phase are discussed. We also examined 4 asynchronous polars, but found no new shells around any of them, so we are unable to confirm that a recent nova eruption is the cause of the asynchronicity in the white dwarf spin. We find tentative evidence of a faint shell around the dwarf nova V1363 Cyg. In addition, we find evidence for a light echo around the nova V2275 Cyg, which erupted in 2001, indicative of an earlier nova eruption approx.300 years ago, making V2275 Cyg a possible recurrent nova.Comment: 14 pages, 50 figures, 3 Table

Pharmacogenomics in early-phase clinical development.

Pharmacogenomics (PGx) offers the promise of utilizing genetic fingerprints to predict individual responses to drugs in terms of safety, efficacy and pharmacokinetics. Early-phase clinical trial PGx applications can identify human genome variations that are meaningful to study design, selection of participants, allocation of resources and clinical research ethics. Results can inform later-phase study design and pipeline developmental decisions. Nevertheless, our review of the clinicaltrials.gov database demonstrates that PGx is rarely used by drug developers. Of the total 323 trials that included PGx as an outcome, 80% have been conducted by academic institutions after initial regulatory approval. Barriers for the application of PGx are discussed. We propose a framework for the role of PGx in early-phase drug development and recommend PGx be universally considered in study design, result interpretation and hypothesis generation for later-phase studies, but PGx results from underpowered studies should not be used by themselves to terminate drug-development programs

First Lunar Occultation Results from the 2.4 m Thai National Telescope equipped with ULTRASPEC

The recently inaugurated 2.4\,m Thai National Telescope (TNT) is equipped, among other instruments, with the ULTRASPEC low-noise, frame-transfer EMCCD camera. At the end of its first official observing season, we report on the use of this facility to record high time resolution imaging using small detector subarrays with sampling as fast as several $10^2$\,Hz. In particular, we have recorded lunar occultations of several stars which represent the first contribution to this area of research made from South-East Asia with a telescope of this class. Among the results, we discuss an accurate measurement of $\alpha$~Cnc, which has been reported previously as a suspected close binary. Attempts to resolve this star by several authors have so far met with a lack of unambiguous confirmation. With our observation we are able to place stringent limits on the projected angular separation (<0\farcs003) and brightness ($\Delta{\rm m} > 5$) of a putative companion. We also present a measurement of the binary {HR~7072}, which extends considerably the time coverage available for its yet undetermined orbit. We discuss our precise determination of the flux ratio and projected separation in the context of other available data. We conclude by providing an estimate of the performance of ULTRASPEC at TNT for lunar occultation work. This facility can help to extend the lunar occultation technique in a geographical area where no comparable resources were available until now.Comment: Accepted for publication in Astronomical Journa

An observational test of common-envelope evolution

By analysing and modelling the change in the abundance ratio of $^{12}$C/$^{13}$C and $^{16}$O/$^{17}$O on the surface of the lower mass star of a binary during the common-envelope (CE) phase of evolution, we propose a simple observational test of the CE scenario. The test is based on the infrared measurement of either the $^{12}$C/$^{13}$C or $^{16}$O/$^{17}$O ratio of red dwarfs in post-common envelope binaries (PCEB's). In certain cases (main-sequence red dwarf secondaries in PCEB's without planetary nebulae), as well as determining whether or not accretion has occurred during the CE phase, we can determine the amount of mass accreted during the CE phase and hence the initial mass of the red dwarf component prior to the CE phase. In the other cases considered (low-mass red dwarfs in PCEB's and red dwarf's in PCEB's with planetary nebulae) we can only say whether or not accretion has occurred during the CE phase.Comment: uuencoded compressed postscript. The preprint are also available at URL http://www.ast.cam.ac.uk/preprint/PrePrint.htm