A research on identifying the need for distance education for national athletes who study in school of physical education and sport

The purpose of this study was to identify the problems which national athletes, who study in School of Physical Education and Sport in universities, encounter in formal education and to determine their need for distance learning. Qualitative research, which is one the techniques of researching the method of the study, forms a structured deliberation technique. Deliberation questions are prepared with this technique based on expert opinions and during the deliberation, the questions were asked to the people who attended the deliberation in a partially flexible way. Population and sampling of the research; population of the study is the people who study in School of Physical Education and Sports, and sampling is the 348 national athletes who study wrestling, bocce, dart, bowling, basketball, volleyball, football, taekwando, karate, archery, atheism, tennis, judo, badminton, table tennis, boxing, weight lifting, handball, gymnastics and swimming in School of Physical Education and Sports. %20.4 of these sportsmen are female, %79.6 of them are male and %78.7 of them are between 19-25 years old, %14.4 of them are between 26-30 years old, %4.3 of them are between 31-35 years old, and %2.6 of them are 36 years old and older. %26.4 of the sportsmen who attend the research, study Coaching, %49.7 of them study Profession of Teaching, %14.1 of them study Sport Management and %9.8 of them study Recreation. And %97.7 of these sportsmen receive undergraduate education, %2.3 of them receive graduate education. At the end of the study, the national athletes, who attended the research, emphasized that they were having problems in formal education, they failed the exams because they couldn't follow the courses, when they had to attend the courses, they delayed their trainings, and this situation effected their education level. %87.9 of the national athletes who took part in the study pointed that they need distance learning and if such a programme is developed, they could follow the courses even when they were resting in the camping and they think that a programme like this must be developed as soon as possible

Expression of Cationic Amino Acid Transporter 2 Is Required for Myeloid-Derived Suppressor Cell-Mediated Control of T Cell Immunity

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature cells that expand during benign and cancer-associated inflammation and are characterized by their ability to inhibit T cell immunity. Increased metabolism of l-Arginine (l-Arg), through the enzymes arginase 1 and NO synthase 2 (NOS2), is well documented as a major MDSC suppressive mechanism. Therefore, we hypothesized that restricting MDSC uptake of l-Arg is a critical control point to modulate their suppressor activity. Using murine models of prostate-specific inflammation and cancer, we have identified the mechanisms by which extracellular l-Arg is transported into MDSCs. We have shown that MDSCs recruited to localized inflammation and tumor sites upregulate cationic amino acid transporter 2 (Cat2), coordinately with Arg1 and Nos2. Cat2 expression is not induced in MDSCs in peripheral organs. CAT2 contributes to the transport of l-Arg in MDSCs and is an important regulator of MDSC suppressive function. MDSCs that lack CAT2 have significantly reduced suppressive ability ex vivo and display impaired capacity for regulating T cell responses in vivo as evidenced by increased T cell expansion and decreased tumor growth in Cat2(-/-) mice. The abrogation of suppressive function is due to low intracellular l-Arg levels, which leads to the impaired ability of NOS2 to catalyze l-Arg-dependent metabolic processes. Together, these findings demonstrate that CAT2 modulates MDSC function. In the absence of CAT2, MDSCs display diminished capacity for controlling T cell immunity in prostate inflammation and cancer models, where the loss of CAT2 results in enhanced antitumor activity

Comparative anatomy of the porcine and human thoracic spines with reference to thoracoscopic surgical techniques

Background: This study compared porcine and human thoracic spine anatomies for a better understanding of how structures encountered during thoracoscopy differ between training with a porcine model and actual surgery in humans. Methods: Parameters were measured including vertebral body height, width, and depth; disc height; rib spacing; spinal canal depth and width; and pedicle height and width. Results: Although most porcine vertebral structures were smaller, porcine pedicle height was significantly greater than that of humans because the porcine pedicle houses a unique transverse foramen. The longus colli and psoas attach, respectively, to T5 and T13 in swine and to T3 and T12 in humans. In swine, the azygos vein generally was absent. The intercostal veins drained into the hemiazygos vein. Conclusions: Several thoracoscopically relevant anatomic differences between human and porcine spinal anatomies were identified. A thoracoscopic approach in a porcine model probably is best performed from the right side. The best general working area is between T6 and T10. © Springer Science+Business Media, Inc. 2005