Precision characterisation of two-qubit Hamiltonians via entanglement mapping

We show that the general Heisenberg Hamiltonian with non-uniform couplings can be characterised by mapping the entanglement it generates as a function of time. Identification of the Hamiltonian in this way is possible as the coefficients of each operator control the oscillation frequencies of the entanglement function. The number of measurements required to achieve a given precision in the Hamiltonian parameters is determined and an efficient measurement strategy designed. We derive the relationship between the number of measurements, the resulting precision and the ultimate discrete error probability generated by a systematic mis-characterisation, when implementing two-qubit gates for quantum computing.Comment: 6 Pages, 3 figure

Soy versus whey protein bars: Effects on exercise training impact on lean body mass and antioxidant status

BACKGROUND: Although soy protein may have many health benefits derived from its associated antioxidants, many male exercisers avoid soy protein. This is due partly to a popular, but untested notion that in males, soy is inferior to whey in promoting muscle weight gain. This study provided a direct comparison between a soy product and a whey product. METHODS: Lean body mass gain was examined in males from a university weight training class given daily servings of micronutrient-fortified protein bars containing soy or whey protein (33 g protein/day, 9 weeks, n = 9 for each protein treatment group). Training used workouts with fairly low repetition numbers per set. A control group from the class (N = 9) did the training, but did not consume either type protein bar. RESULTS: Both the soy and whey treatment groups showed a gain in lean body mass, but the training-only group did not. The whey and training only groups, but not the soy group, showed a potentially deleterious post-training effect on two antioxidant-related related parameters. CONCLUSIONS: Soy and whey protein bar products both promoted exercise training-induced lean body mass gain, but the soy had the added benefit of preserving two aspects of antioxidant function

Quantum circuits with many photons on a programmable nanophotonic chip

Growing interest in quantum computing for practical applications has led to a surge in the availability of programmable machines for executing quantum algorithms. Present day photonic quantum computers have been limited either to non-deterministic operation, low photon numbers and rates, or fixed random gate sequences. Here we introduce a full-stack hardware-software system for executing many-photon quantum circuits using integrated nanophotonics: a programmable chip, operating at room temperature and interfaced with a fully automated control system. It enables remote users to execute quantum algorithms requiring up to eight modes of strongly squeezed vacuum initialized as two-mode squeezed states in single temporal modes, a fully general and programmable four-mode interferometer, and genuine photon number-resolving readout on all outputs. Multi-photon detection events with photon numbers and rates exceeding any previous quantum optical demonstration on a programmable device are made possible by strong squeezing and high sampling rates. We verify the non-classicality of the device output, and use the platform to carry out proof-of-principle demonstrations of three quantum algorithms: Gaussian boson sampling, molecular vibronic spectra, and graph similarity

The curious compatibility of consensus, corporatism, and neoliberalism : The Finnish business community and the retasking of a corporatist welfare state

This article addresses the apparent paradox of simultaneous neoliberal change and welfare-statist, corporatist continuity by presenting an empirical case study of the advent of neoliberal ideas in Finland in the 1970s and 1980s. The article focuses on the attempts of a free-market think tank, EVA, and the employers’ association, STK, to advance policies such as economic deregulation, international competitiveness, welfare retrenchment, and active social and labour market policies through the neoliberal retasking of the corporatist Finnish welfare state. EVA and the STK utilised seemingly non-neoliberal means, that is an economic policy consensus and tripartite corporatist arrangements, and reformulated their content to better correspond with business interests. Instead of demolition, the outcome has been the redefinition and incremental transformation of the state from a provider of welfare to a promoter of competitiveness, productivity, and employment.Peer reviewe

Aurora kinases are expressed in medullary thyroid carcinoma (MTC) and their inhibition suppresses in vitro growth and tumorigenicity of the MTC derived cell line TT

International audienceBACKGROUND: The Aurora kinase family members, Aurora-A, -B and -C, are involved in the regulation of mitosis, and alterations in their expression are associated with cell malignant transformation. To date no information on the expression of these proteins in medullary thyroid carcinoma (MTC) are available. We here investigated the expression of the Aurora kinases in human MTC tissues and their potential use as therapeutic targets. METHODS: The expression of the Aurora kinases in 26 MTC tissues at different TNM stages was analyzed at the mRNA level by quantitative RT-PCR. We then evaluated the effects of the Aurora kinase inhibitor MK-0457 on the MTC derived TT cell line proliferation, apoptosis, soft agar colony formation, cell cycle and ploidy. RESULTS: The results showed the absence of correlation between tumor tissue levels of any Aurora kinase and tumor stage indicating the lack of prognostic value for these proteins. Treatment with MK-0457 inhibited TT cell proliferation in a time- and dose-dependent manner with IC50 = 49.8 ± 6.6 nM, as well as Aurora kinases phosphorylation of substrates relevant to the mitotic progression. Time-lapse experiments demonstrated that MK-0457-treated cells entered mitosis but were unable to complete it. Cytofluorimetric analysis confirmed that MK-0457 induced accumulation of cells with ≥ 4N DNA content without inducing apoptosis. Finally, MK-0457 prevented the capability of the TT cells to form colonies in soft agar. CONCLUSIONS: We demonstrate that Aurora kinases inhibition hampered growth and tumorigenicity of TT cells, suggesting its potential therapeutic value for MTC treatment