The Ohio State University Counseling Center: Historical Sketches, 1941-1969

Prepared for the Centennial of The Ohio State University

Did local civil rights protest liberalize whites’ racial attitudes?

Mazumder investigates the long-term effect of protest on political attitudes. He finds that whites have more liberal views on race and are more likely to be Democrats in counties where Civil Rights protest was reported in the early 1960s. The analysis omits a crucial predictor of protest and of racial attitudes: college education. We include the proportion of adults with a college degree and the number of college students at the county level. The inclusion of these variables, along with some other contextual variables from the original dataset, cuts the effect of protest by about half. Protest is no longer statistically significant in eight out of nine combinations of outcome variables and protest measures. The size of the effect remains trivial when we shift analysis from the county to the individual level. Even accounting for the individual’s own education, the county’s proportion of college graduates is strongly associated with racial liberalism. This finding emphasizes the importance of education as a contextual variable. Our conclusion highlights two methodological lessons. First, causal inference should be paired with sustained historical inquiry that specifies plausible mechanisms. Second, statistical tests for sensitivity can induce complacency about the risk of confounding

Australian co-operation with the national agricultural research project - Project Completion Report 1990

This Project Completion Report (PCR) has been written to meet the project monitoring requirements of AIDAB. Because the ACNARP Project was part of a larger joint WB/IFAD project known as the National Agricultural Research Project (NARP), a summary of ACNARP and its progress and achievements, cannot be divorced from NARP. The report should therefore be read within the context that ACNARP alone has not been responsible for all the developments and achievements listed. Achievements in relation to some of the project objectives have been the result of Thai inputs, often with advice from ACNARP, rather than being able to be attributed solely to ACNARP. There were also some objectives and components of the larger WB/IFAD NARP Project, for which there were no corresponding specific ACNARP inputs

Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion

Magnetic resonance imaging (MRI) with oxygen challenge (T2* OC) uses oxygen as a metabolic biotracer to define penumbral tissue based on CMRO2 and oxygen extraction fraction. Penumbra displays a greater T2* signal change during OC than surrounding tissue. Since timely restoration of cerebral blood flow (CBF) should salvage penumbra, T2* OC was tested by examining the consequences of reperfusion on T2* OC-defined penumbra. Transient ischemia (109±20 minutes) was induced in male Sprague-Dawley rats (n=8). Penumbra was identified on T2*-weighted MRI during OC. Ischemia and ischemic injury were identified on CBF and apparent diffusion coefficient maps, respectively. Reperfusion was induced and scans repeated. T2 for final infarct and T2* OC were run on day 7. T2* signal increase to OC was 3.4% in contralateral cortex and caudate nucleus and was unaffected by reperfusion. In OC-defined penumbra, T2* signal increased by 8.4%±4.1% during ischemia and returned to 3.25%±0.8% following reperfusion. Ischemic core T2* signal increase was 0.39%±0.47% during ischemia and 0.84%±1.8% on reperfusion. Penumbral CBF increased from 41.94±13 to 116.5±25 mL per 100 g per minute on reperfusion. On day 7, OC-defined penumbra gave a normal OC response and was located outside the infarct. T2* OC-defined penumbra recovered when CBF was restored, providing further validation of the utility of T2* OC for acute stroke management

Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography

Accurate identification of ischemic penumbra will improve stroke patient selection for reperfusion therapies and clinical trials. Current magnetic resonance imaging (MRI) techniques have limitations and lack validation. Oxygen challenge T2* MRI (T2* OC) uses oxygen as a biotracer to detect tissue metabolism, with penumbra displaying the greatest T2* signal change during OC. [14C]2-deoxyglucose (2-DG) autoradiography was combined with T2* OC to determine metabolic status of T2*-defined penumbra. Permanent middle cerebral artery occlusion was induced in anesthetized male Sprague-Dawley rats (n=6). Ischemic injury and perfusion deficit were determined by diffusion- and perfusion-weighted imaging, respectively. At 147±32 minutes after stroke, T2* signal change was measured during a 5-minute 100% OC, immediately followed by 125 μCi/kg 2-DG, intravenously. Magnetic resonance images were coregistered with the corresponding autoradiograms. Regions of interest were located within ischemic core, T2*-defined penumbra, equivalent contralateral structures, and a region of hyperglycolysis. A T2* signal increase of 9.22%±3.9% (mean±s.d.) was recorded in presumed penumbra, which displayed local cerebral glucose utilization values equivalent to contralateral cortex. T2* signal change was negligible in ischemic core, 3.2%±0.78% in contralateral regions, and 1.41%±0.62% in hyperglycolytic tissue, located outside OC-defined penumbra and within the diffusion abnormality. The results support the utility of OC-MRI to detect viable penumbral tissue follow

GEM/POPs: a global 3-D dynamic model for semi-volatile persistent organic pollutants ? Part 2: Global transports and budgets of PCBs

International audienceGlobal transports and budgets of three PCBs were investigated with a 3-D dynamic model for semi-volatile persistent organic pollutants ? GEM/POPs. Dominant pathways were identified for PCB transports in the atmosphere with a transport flux peaking below 8 km for gaseous and 14 km for particulate PCB28, and peaking below 4 km for gaseous and 6 km for particulate PCB180. The inter-continental transports of PCBs in the Northern Hemisphere (NH) are dominated in the zonal direction with their route changes regulated seasonally by the variation of westerly jet. The transport pathways from Europe and North Atlantic contributed the most PCBs to the Arctic. Inter-hemispheric transports of PCBs originated from the regions of Europe, Asia and North America in three different flow-paths, accompanying with easterly jet, Asian monsoon winds and trade winds. PCBs from the Southern Hemisphere (SH) could also be exported into the NH. According to the PCB emissions of year 2000, Europe, North America and Asia are the three largest sources of the three PCBs, contributing to the global background concentrations in the atmosphere, soil and water. Globally, PCB28 in soil and water has become a comparable source to the anthropogenic emissions while heavier PCBs such as PCB153 and 180 are still transporting into soil and water. For all three congeners, particulate PCBs are concentrated in the higher levels than gaseous PCBs. More than half of the particulate PCB28 could reach up to the stratosphere, while most of the heavier counter-parts (PCB153 and PCB180) are stored in the troposphere including boundary layer with more than 99% gaseous PCB180 below 6 km