Inovasi Pendidikan Sains di Indonesia Bagi Masa Depan Bangsa

Prosiding Seminar Nasional Pendidikan Sains II : Inovasi dan Pengembangan Kualitas Pembelajaran Sains Berbasis Pendidikan Karakter dan Teknologi di Era MEA, Salatiga, 22 April 2017, p. 11-17Makalah ini membahas pentingnya melakukan terobosan-terobosan inovatif untuk memajukan pendidikan sains di Indonesia bagi masa depan bangsa serta berbagai tantangan yang dihadapi. Dipaparkan pula dalam tulisan ini, perubahan peran guru yang bertugas mendidik generasi digital, penerapan flip classroom dalam proses pembelajaran sains, serta langkah-langkah awal inovasi pembelajaran sains berbasis teknologi informasi dan komunikas

INTERNAL CONTROL ROLE IN RELATIONSHIP BETWEEN EMPLOYEE AND PUBLIC SECTOR ORGANIZATIONS

This study aims to obtain empirical evidence of the impact of employee’s Public Service Motivation (PSM) and Organizational Commitment on the Organizational Performance through Internal Control System (ICS) as an intervening variable. The study was conducted on all State Civil Employees at the State Treasury Services Office in Bali Province through a survey on 98 respondents and was analyzed with SEM-PLS. The results show that Organizational Performance improvement in order to achieve performance contract’s designated targets done by increasing employee’s motivation and commitment. PSM and Organizational Commitment play an important role in goals achievement, and without both variables, the performance management will not lead to higher public services quality. Public sector organizations can make ICS as a tool to controls over employee’s motivation and commitment. The integrated ICS within the organizational unit structure is not only able to controls the overall business process but also on the employee’s daily work life

The Relationship between Expression of p70s6k with Radiotherapy Response in Cervical Cancer

There are many important prognostic factors in advanced stage cervical cancer primary treated with radiotherapy. Besides clinical factors, many biomarkers have been studied in relation with radiotherapy response. The p70s6k is a biomarker which plays a significant role in cell proliferation. Increased levels of p70s6k are also associated with drug resistance in cancer. In the present study, the relationship between the expression level of p70s6k before treatment and the radiotherapy response in cervical cancer was determined. Immunohistochemical staining of p70s6k, MIB-1, and p53 was conducted in microscopic slide from 21 cancer tissue biopsies before treatment with radiotherapy. After the treatment had completed early radiotherapy response was observed by pelvic control method. The results showed that p70s6k is partly highly expressed (61.9%, 13/21) and partly low expressed (38.1%, 8/21) in the cancer cells. They also show that there is no statistically significant differences on AgNOR mean, MIB-1, and p53 indices in the different degrees of p70s6k expression (p≥0.05). Higher expression levels of p70s6k is more strongly associated with good radiotherapy response compared to lower ones (p=0.05). In conclusion, the level of p70s6k expression before treatment has an association with radiotherapy response

The Relationship between Expression of p70s6k with Radiotherapy Response in Cervical Cancer

There are many important prognostic factors in advanced stage cervical cancer primary treated with radiotherapy. Besides clinical factors, many biomarkers have been studied in relation with radiotherapy response. The p70s6k is a biomarker which plays a significant role in cell proliferation. Increased levels of p70s6k are also associated with drug resistance in cancer. In the present study, the relationship between the expression level of p70s6k before treatment and the radiotherapy response in cervical cancer was determined. Immunohistochemical staining of p70s6k, MIB-1, and p53 was conducted in microscopic slide from 21 cancer tissue biopsies before treatment with radiotherapy. After the treatment had completed early radiotherapy response was observed by pelvic control method. The results showed that p70s6k is partly highly expressed (61.9%, 13/21) and partly low expressed (38.1%, 8/21) in the cancer cells. They also show that there is no statistically significant differences on AgNOR mean, MIB-1, and p53 indices in the different degrees of p70s6k expression (p≥0.05). Higher expression levels of p70s6k is more strongly associated with good radiotherapy response compared to lower ones (p=0.05). In conclusion, the level of p70s6k expression before treatment has an association with radiotherapy response

The Relationship between Expression of p70s6k with Radiotherapy Response in Cervical Cancer

There are many important prognostic factors in advanced stage cervical cancer primary treated with radiotherapy. Besides clinical factors, many biomarkers have been studied in relation with radiotherapy response. The p70s6k is a biomarker which plays a significant role in cell proliferation. Increased levels of p70s6k are also associated with drug resistance in cancer. In the present study, the relationship between the expression level of p70s6k before treatment and the radiotherapy response in cervical cancer was determined. Immunohistochemical staining of p70s6k, MIB-1, and p53 was conducted in microscopic slide from 21 cancer tissue biopsies before treatment with radiotherapy. After the treatment had completed early radiotherapy response was observed by pelvic control method. The results showed that p70s6k is partly highly expressed (61.9%, 13/21) and partly low expressed (38.1%, 8/21) in the cancer cells. They also show that there is no statistically significant differences on AgNOR mean, MIB-1, and p53 indices in the different degrees of p70s6k expression (p≥0.05). Higher expression levels of p70s6k is more strongly associated with good radiotherapy response compared to lower ones (p=0.05). In conclusion, the level of p70s6k expression before treatment has an association with radiotherapy response