71 research outputs found
#COVIDisAirborne: AI-enabled multiscale computational microscopy of delta SARS-CoV-2 in a respiratory aerosol
We seek to completely revise current models of airborne transmission of respiratory viruses by providing never-before-seen atomic-level views of the SARS-CoV-2 virus within a respiratory aerosol. Our work dramatically extends the capabilities of multiscale computational microscopy to address the significant gaps that exist in current experimental methods, which are limited in their ability to interrogate aerosols at the atomic/molecular level and thus obscure our understanding of airborne transmission. We demonstrate how our integrated data-driven platform provides a new way of exploring the composition, structure, and dynamics of aerosols and aerosolized viruses, while driving simulation method development along several important axes. We present a series of initial scientific discoveries for the SARS-CoV-2 Delta variant, noting that the full scientific impact of this work has yet to be realized
Politics versus policy: the role of northern politics and foreign policy in the 2006 conservative election campaign
Bibliography: p. 101-10
Recommended from our members
Biophysical investigation of acyl-carrier and SARS-CoV-2 protein communication mechanisms
Proteins are one of the primary macromolecules that carry out the many essential functions of life. They catalyze chemical reactions, provide structural integrity, and perform biological motor functions. Proteins dynamically interact with surrounding molecules by diffusing, binding, and changing conformations, signaling their stage in biochemical processes. Interpreting these signals is key to harnessing control over protein function for beneficial purposes, such as inhibiting disease related proteins and synthesizing desired molecules including biofuels and therapeutics. This dissertation investigates the communication mechanisms of two protein classes: acyl carrier proteins (ACPs) and SARS-CoV-2 viral proteins. The methods and fundamental properties uncovered herein are expected to be applicable to a broad range of protein systems
- …