75 research outputs found
Orthostatic responses to dietary sodium restriction during heat acclimation
Several studies have shown that individuals consuming low-salt diets and working in the heat have an increased risk or incidence of heat injury, suggestive of inadequate cardiovascular adjustment. Furthermore, others have shown that prolonged work in hot climates can precipitate orthostatic hypotension and syncope. This study was designed to evaluate the effects of moderate-salt (MS) and low-salt (LS) diets on the circulatory responses and incidence of presyncopal symptoms to an orthostatic test (OT) during successive days of heat acclimation (HA). Seventeen unacclimatized male soldiers (mean +/- SE: age 20+/-1 yrs) participated in this two-phase study. The first phase consisted of a seven day dietary stabilization period during which all subjects consumed similar diets of about 4000 kcal/day containing 8g NaCl and lived in a dormitory setting (21 C, 30% RH). The second phase commenced on day eight and consisted of dietary NaCl restriction and 10 days HA (days 8-17). Volunteers were randomly assigned to either the MS diet (n=9) providing 8g NaCl/day or the LS diet (n=8) furnishing just 4g NaCl/day. The acquisition of HA was manifested in both groups by reductions in exercising rectal temperature and heart rate (HR); these characteristics were similar in the MS and LS diets. The OT was performed at 21 C on day seven of the stabilization phase and on days 9, 11, 13, 15, and 17 of the HA phase, before and after 8.5 hr of intermittent treadmill walking in a hot environment. Blood pressure (BP) and HR responses at 1,2, and 4 min and any presyncopal symptoms were recorded after assuming an upright position from recumbency. All subjects completed the OT before and after prolonged exercise in the heat without incidence of either hypotension or presyncopal symptoms irrespective of dietary-salt intake and day of HA. The results indicate that the prolonged work in the heat can be performed without orthostatic hypotension or syncope while consuming 4g NaCl/day with adequate fluid replacement. Furthermore, the circulatory responses to OT showed no improvement with successive days of HA irrespective of dietary-salt intake
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Eye movements during visual search in patients with glaucoma
Background: Glaucoma has been shown to lead to disability in many daily tasks including visual search. This study aims to determine whether the saccadic eye movements of people with glaucoma differ from those of people with normal vision, and to investigate the association between eye movements and impaired visual search.
Methods: Forty patients (mean age: 67 [SD: 9] years) with a range of glaucomatous visual field (VF) defects in both eyes (mean best eye mean deviation [MD]: –5.9 (SD: 5.4) dB) and 40 age-related people with normal vision (mean age: 66 [SD: 10] years) were timed as they searched for a series of target objects in computer displayed photographs of real world scenes. Eye movements were simultaneously recorded using an eye tracker. Average number of saccades per second, average saccade amplitude and average search duration across trials were recorded. These response variables were compared with measurements of VF and contrast sensitivity.
Results: The average rate of saccades made by the patient group was significantly smaller than the number made by controls during the visual search task (P = 0.02; mean reduction of 5.6% (95% CI: 0.1 to 10.4%). There was no difference in average saccade amplitude between the patients and the controls (P = 0.09). Average number of saccades was weakly correlated with aspects of visual function, with patients with worse contrast sensitivity (PR logCS; Spearman’s rho: 0.42; P = 0.006) and more severe VF defects (best eye MD; Spearman’s rho: 0.34; P = 0.037) tending to make less eye movements during the task. Average detection time in the search task was associated with the average rate of saccades in the patient group (Spearman’s rho = −0.65; P < 0.001) but this was not apparent in the controls.
Conclusions: The average rate of saccades made during visual search by this group of patients was fewer than those made by people with normal vision of a similar average age. There was wide variability in saccade rate in the patients but there was an association between an increase in this measure and better performance in the search task. Assessment of eye movements in individuals with glaucoma might provide insight into the functional deficits of the disease
Convergence of Self-Report and Archival Crash Involvement Data: A Two-Year Longitudinal Follow-Up
This study constructively extends Arthur et al. (2001) by assessing the convergence of self-report and archival motor vehicle crash involvement and moving violations data in a 2-year longitudinal follow-up. The relationships among these criteria, conscientiousness, and driving speed were also assessed using both predictive and postdictive criterion-related validation designs. Data were collected from a 2-year follow-up sample of 334 participants. Results suggested a lack of convergence between self-report and archival data at both Time 1 and Time 2. In addition, the predictor/criterion relationships varied across research design and data source. An actual application of our findings is that the interpretation of relationships between specified predictors and crash involvement and moving violations must be made within the context of the criterion-related validation design and criterion data source. Specifically, predictive designs may produce results different from those of postdictive designs (which are more commonly used). Furthermore, self-report data appear to include a broader range of incidents (more crashes and tickets), and thus researchers should consider using self-report data when they are interested in including lower threshold crashes and tickets that may not be reported on state records (e.g., because of the completion of a defensive driving course)Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
Age-dependent visual exploration during simulated day- and night driving on a motorway: a cross-sectional study
Atypical Balance between Occipital and Fronto-Parietal Activation for Visual Shape Extraction in Dyslexia
Reading requires the extraction of letter shapes from a complex background of text, and an impairment in visual shape extraction would cause difficulty in reading. To investigate the neural mechanisms of visual shape extraction in dyslexia, we used functional magnetic resonance imaging (fMRI) to examine brain activation while adults with or without dyslexia responded to the change of an arrow’s direction in a complex, relative to a simple, visual background. In comparison to adults with typical reading ability, adults with dyslexia exhibited opposite patterns of atypical activation: decreased activation in occipital visual areas associated with visual perception, and increased activation in frontal and parietal regions associated with visual attention. These findings indicate that dyslexia involves atypical brain organization for fundamental processes of visual shape extraction even when reading is not involved. Overengagement in higher-order association cortices, required to compensate for underengagment in lower-order visual cortices, may result in competition for top-down attentional resources helpful for fluent reading.Ellison Medical FoundationMartin Richmond Memorial FundNational Institutes of Health (U.S.). (Grant UL1RR025758)National Institutes of Health (U.S.). (Grant F32EY014750-01)MIT Class of 1976 (Funds for Dyslexia Research
Work-related road safety: An analysis based on U.K. bus driver performance
The effects of age and experience on accident involvement for bus drivers were
investigated, with special emphasis upon the first years of being an operator,
using two methods. First, direct calculations between these variables were
undertaken. Thereafter, a variant of the method of quasi-induced exposure (a
ratio of culpable versus nonculpable accidents in the population) was used and
referred to as the indirect method. These methods yielded fairly similar
results, given that the samples used were drawn from the same population but
only partly overlapping. It was found that experience had the strongest effect
on accidents in the first year of driving, while age had a u-shaped association
with accidents, that is, young and old drivers had more accidents, something
that was more apparent when experience was held constant. These results show
that, for bus drivers, experience is initially more important than age, but
after two or three years, the effect is small. Thereafter, age is the more
discernible variable, although it is a very weak factor in predicting crash
risk
Is Engagement in Physical Activity Related to Its Perceived Mental Health Benefits Among People With Depression and Anxiety?:A Population-Scale Survey Study
Compensatory viewing training improves practical fitness to drive of subjects with impaired vision
In many countries strict legal requirements for obtaining a
driver’s license are in effect for visual acuity and visual field.We studied the relationship between these characteristics and driving safety and driving proficiency in an on-the-road test of practical fitness to drive in subjects with visual disorders, including many subjects scoring below current criteria. We further studied how far the relationship between the on-the-road test and visual measures improved if compensatory eye movements and visual attention were included in the criteria. Lastly, we studied the effects of training compensatory viewing strategiesformed the on-the-road test before and after training. Training consisted of laboratory and mobility training, including driving instruction. Visual function assessment included acuity, visual field, contrast sensitivity, visual attention, compensatory viewing efficiency, and visuospatial tests. In one study an advanced driving simulator was used besides the on-the-road assessment. Two models were compared to predict the on-the-road score.
Results: 13–62% of the subjects passed the on-the-road test before training. After training, an additional 15–45% passed. The power of both models to predict the on-the-road score rose to about 45% by adding viewing behavior in the driving simulator.
Discussion: A considerable percentage of the subjects, legally not allowed to drive, passed the on-the-road test. Sensitivity and specificity of vision tests and driving simulator tests are still too low to decide upon unfitness to drive. Training of compensatory viewing improved
the performance in the on-the-road test.
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