8 research outputs found
Postoperative analgesic effect, of preoperatively administered dexamethasone, after operative fixation of fractured neck of femur: randomised, double blinded controlled study.
Background: Fractured neck of femur is a common cause of hospital admission in the elderly and usually requires operative fixation. In a variety of clinical settings, preoperative glucocorticoid administration has improved analgesia and decreased opioid consumption. Our objective was to define the postoperative analgesic efficacy of single dose of dexamethasone administered preoperatively in patients undergoing operative fixation of fractured neck of femur. Methods: Institutional ethical approval was granted and written informed consent was obtained from each patient. Patients awaiting for surgery at Cork University Hospital were recruited between July 2009 and August 2012. Participating patients, scheduled for surgery were randomly allocated to one of two groups (Dexamethasone or Placebo). Patients in the dexamethasone group received a single dose of intravenous dexamethasone 0.1 mg kg -1 immediately preoperatively. Patients in the placebo group received the same volume of normal saline. Patients underwent operative fixation of fractured neck of femur using standardised spinal anaesthesia and surgical techniques. The primary outcome was pain scores at rest 6 h after the surgery. Results: Thirty seven patients were recruited and data from thirty patients were analysed. The groups were similar in terms of patient characteristics. Pain scores at rest 6 h after the surgery (the principal outcome) were lesser in the dexamethasone group compared with the placebo group [0.8(1.3) vs. 3.9(2.9), mean(SD) p = 0.0004]. Cumulative morphine consumption 24 h after the surgery was also lesser in the dexamethasone group [7.7(8.3) vs. 15.1(9.4), mean(SD) mg, p = 0.04]. Conclusions: A single dose of intravenous dexamethasone 0.1 mg kg -1 administered before operative fixation of fractured neck of femur improve significantly the early postoperative analgesia. Trial registration: ClinicalTrials.gov identifier: NCT01550146, date of registration: 07/03/201
Analgesic efficacy of continuous femoral nerve block commenced prior to operative fixation of fractured neck of femur
Abstract Background Peripheral nerve blocks are effective in treating acute pain, thereby minimizing the requirement for opiate analgesics. Fractured neck of femur (FNF) is a common, painful injury. The provision of effective analgesia to this cohort is challenging but an important determinant of their functional outcome. We investigated the analgesic efficacy of continuous femoral nerve block (CFNB) in patients with FNF. Methods Following institutional ethical approval and with informed consent, patients awaiting FNF surgery were randomly allocated to receive either standard opiate-based analgesia (Group 1) or a femoral perineural catheter (Group 2). Patients in Group 1 received parenteral morphine as required. Those in Group 2 received a CFNB comprising a bolus of local anaesthetic followed by a continuous infusion of 0.25% bupivacaine. For both Groups, rescue analgesia consisted of intramuscular morphine as required and all patients received paracetamol regularly. Pain was assessed using a visual analogue scale at rest and during passive movement (dynamic pain score) at 30 min following first analgesic intervention and six hourly thereafter for 72 hours. Patient satisfaction with the analgesic regimen received was recorded using verbal rating scores (0-10). The primary outcome measured was dynamic pain score from initial analgesic intervention to 72 hours later. Results Of 27 recruited, 24 patients successfully completed the study protocol and underwent per protocol analysis. The intervals from recruitment to the study until surgery were similar in both groups [31.4(17.7) vs 27.5(14.2) h, P = 0.57]. The groups were similar in terms of baseline clinical characteristics. For patients in Group 2, pain scores at rest were less than those reported by patients in Group 1 [9.5(9.4) vs 31(28), P = 0.031]. Dynamic pain scores reported by patients in Group 2 were less at each time point from 30 min up to 54 hours [e.g at 6 h 30.7(23.4) vs 67.0(32.0), P = 0.004]. Cumulative morphine consumption over 72 h was less in Group 2. Patient satisfaction scores were greater in Group 2 [9.4(1.1) vs 7.6(1.8), P = 0.014]. Conclusions CFNB provides more effective perioperative analgesia than a standard opiate-based regimen for patients undergoing fixation of FNF. It is associated with lesser opiate use and greater patient satisfaction.</p
Continuous Femoral Nerve Block Versus Fascia Iliaca Compartment Block as Postoperative Analgesia in Patients with Hip Fracture
Chronic pancreatitis. Multicentre prospective data collection and analysis by the Hungarian Pancreatic Study Group
Postoperative analgesic effect, of preoperatively administered dexamethasone, after operative fixation of fractured neck of femur: randomised, double blinded controlled study
Agricultural economics and transition: What was expected, what we observed, the lessons learned Proceedings (Volume I / II)
Over fifteen years have elapsed since the transition from the centrally planned
economic system started in the early 1990’s. During this time agricultural and
rural areas of Central and Eastern Europe have undergone profound structural
changes with wide variations in the degree of transformation and in the rate of
success in creating a competitive market and private ownership based food and
agricultural system. By becoming member of the European Union the "transition"
in its traditional interpretation has been concluded in ten of the Central East
European countries. The transition to market based agriculture, however, is far
from completion in Southern and Eastern Europe and especially in the CIS
countries.
International Association of Agricultural Economists (IAAE) and European
Association of Agricultural Economists (EAAE) in collaboration with the
Corvinus University of Budapest and with a number of other institutions in
Hungary organized an inter-conference seminar on the subject of agricultural
transition in Central and Eastern Europe and Central Asia. The major objective
of the seminar was to discuss and draw conclusions on the role of agricultural
policy in the transition process in the light of actual progress and current situation
in Central and East European countries and in formal Soviet States. In addition
the contribution of agricultural economics – both from the West and from the
East – as a discipline and a profession to the transition process in agriculture were
discussed. A specific objective was to identify priorities and means to strengthen
the agricultural economics profession in the transition countries and determine
research and educational priorities for the future.
The seminar was attended by 118 participants representing 26 countries from
Europe, North America and Asia. The Seminar was the largest professional
meeting organized by the two associations in 2007. Over 110 abstracts were
submitted and evaluated by the International Program Committee. In the two
day program of the meeting, 8 presentations were made during the 3 plenary
sessions, 66 papers were presented in the 15 contributed paper sessions in 8 subject
categories. In addition there were 15 posters discussed in the poster session and
the findings of a World Bank study on distortions of agricultural incentives in
the region was the subject of a pre-conference workshop. Plenary speakers
included Ulrich Koester, Johan Swinnen, Jerzy Wilkin, Zvi Lerman, Eugenia
Serova and József Popp-Gábor Udovecz. At the end of the seminar David Colman, President of IAAE gave a global assessment of the status of agricultural
economics discipline and profession, while Csaba Csáki, former President of
IAAE made summary comments on major issues discussed during the seminar.
This volume includes the plenary and contributed papers presented at the seminar
and submitted for publications by the authors as well as the abstracts of the poster
papers discussed.
The seminar was supported and sponsored by a number of organizations and
persons. All of their contributions have to be greatly acknowledged. First the
two international organizations IAAE and EAAE have to be mentioned, which
provided overall organizational framework and logistical support. The IAAE
provided in addition a generous grant to support the participation of young
agricultural economists from Central and Eastern Europe on the seminar. On the
Hungarian side the Corvinus University of Budapest, the Szent István University
of Gödöllő, the Research Institute for Agricultural Economics, the Hungarian
Agricultural Economics Association, the Hungarian Association of Agricultural
Sciences and the Hungarian Ministry of Agriculture and Rural Development
were the major material and organizational supporters. The International Program
committee was chaired by David Colman and Csaba Csáki and included
Ulrich Koester, Joe Swinnen, Eugenia Serova and Jerzy Wilkin. The local
Organizing committee was chaired by Csaba Forgács and István Szűcs and
included Zoltán Lakner, András Nábrádi, József Popp, József Tóth, Gábor Udovecz,
László Vajda, László Villányi, Krisztina Fodor, Attila Jámbor and Tamás Mizik.
Finally IAMO, Halle facilitated the publication of this proceedings
Agricultural economics and transition: What was expected, what we observed, the lessons learned Proceedings (Volume I / II)
Over fifteen years have elapsed since the transition from the centrally planned economic system started in the early 1990âs. During this time agricultural and rural areas of Central and Eastern Europe have undergone profound structural changes with wide variations in the degree of transformation and in the rate of success in creating a competitive market and private ownership based food and agricultural system. By becoming member of the European Union the "transition" in its traditional interpretation has been concluded in ten of the Central East European countries. The transition to market based agriculture, however, is far from completion in Southern and Eastern Europe and especially in the CIS countries. International Association of Agricultural Economists (IAAE) and European Association of Agricultural Economists (EAAE) in collaboration with the Corvinus University of Budapest and with a number of other institutions in Hungary organized an inter-conference seminar on the subject of agricultural transition in Central and Eastern Europe and Central Asia. The major objective of the seminar was to discuss and draw conclusions on the role of agricultural policy in the transition process in the light of actual progress and current situation in Central and East European countries and in formal Soviet States. In addition the contribution of agricultural economics â both from the West and from the East â as a discipline and a profession to the transition process in agriculture were discussed. A specific objective was to identify priorities and means to strengthen the agricultural economics profession in the transition countries and determine research and educational priorities for the future. The seminar was attended by 118 participants representing 26 countries from Europe, North America and Asia. The Seminar was the largest professional meeting organized by the two associations in 2007. Over 110 abstracts were submitted and evaluated by the International Program Committee. In the two day program of the meeting, 8 presentations were made during the 3 plenary sessions, 66 papers were presented in the 15 contributed paper sessions in 8 subject categories. In addition there were 15 posters discussed in the poster session and the findings of a World Bank study on distortions of agricultural incentives in the region was the subject of a pre-conference workshop. Plenary speakers included Ulrich Koester, Johan Swinnen, Jerzy Wilkin, Zvi Lerman, Eugenia Serova and József Popp-Gábor Udovecz. At the end of the seminar David Colman, President of IAAE gave a global assessment of the status of agricultural economics discipline and profession, while Csaba Csáki, former President of IAAE made summary comments on major issues discussed during the seminar. This volume includes the plenary and contributed papers presented at the seminar and submitted for publications by the authors as well as the abstracts of the poster papers discussed. The seminar was supported and sponsored by a number of organizations and persons. All of their contributions have to be greatly acknowledged. First the two international organizations IAAE and EAAE have to be mentioned, which provided overall organizational framework and logistical support. The IAAE provided in addition a generous grant to support the participation of young agricultural economists from Central and Eastern Europe on the seminar. On the Hungarian side the Corvinus University of Budapest, the Szent István University of GödöllÅ, the Research Institute for Agricultural Economics, the Hungarian Agricultural Economics Association, the Hungarian Association of Agricultural Sciences and the Hungarian Ministry of Agriculture and Rural Development were the major material and organizational supporters. The International Program committee was chaired by David Colman and Csaba Csáki and included Ulrich Koester, Joe Swinnen, Eugenia Serova and Jerzy Wilkin. The local Organizing committee was chaired by Csaba Forgács and István Szűcs and included Zoltán Lakner, András Nábrádi, József Popp, József Tóth, Gábor Udovecz, László Vajda, László Villányi, Krisztina Fodor, Attila Jámbor and Tamás Mizik. Finally IAMO, Halle facilitated the publication of this proceedings.Agribusiness, Agricultural Finance, Farm Management, Financial Economics, Industrial Organization, International Development, International Relations/Trade, Land Economics/Use, Production Economics,