Off mass shell effects in associated production of the top quark pair and Higgs boson at a linear collider

We discuss effects related to the fact that the final state particles of a reaction e+ e- -> t \bar{t} H are actually produced and they decay off mass shell. For the intermediate mass Higgs boson, which decays preferably into a b\bar{b}-quark pair, the reaction will be observed through reactions with 8 fermions in the final state. Such reactions, already in the lowest order of the standard model, receive contributions typically from a few dozen thousands of the Feynman diagrams, the vast majority of which constitute background to the signal of associated production of the top quark pair and Higgs boson. In order to illustrate pure off mass shell effects we neglect the background contributions and compare the `signal' cross section with the cross section in the narrow width approximation for e+ e- -> b u \bar{d} \bar{b} mu- \bar{nu}_mu b \bar{b}, which is one of possible detection channels of the associated production of the top quark pair and Higgs boson at a linear collider.Comment: 11 pages, 4 figures, version published in Acta Physica Polonica

Spatial Design for Behavioral Education

The built environment can inadvertently create obstacles for human cognition, emotion, and behavior when ill-designed, neglected, or poorly retrofitted. Deteriorating education facilities exemplify the lack of awareness in regard to the significant relationship between people and their environments. However, simply updating a school does not always accommodate occupant needs, especially for students who are sensitive to external stimuli. Students in behavioral schools who suffer from emotional behavioral disorder (EBD) often display adverse neurological affects from negative life experiences. Common disorders comorbid with EBD, as well as EBD itself, interferes with their ability to control and manage behavior. By identifying common challenges, the proposed behavioral school in Northampton, Massachusetts aims to support the building’s program and occupants to achieve specific goals, i.e. academic standards, and behavioral self-management. Environmental-behavior and neuropsychology principles are implemented in overarching themes including biophilic design, behavior defined space, safety, and transitions. Strategic design elements aim to assist students relearning behavior by clearly defining which behaviors are acceptable in specific spaces within the school and by addressing common cognitions and emotions often associated with the negative behavior. These implementations range from broad environmental-behavioral-neurology principles that manifest themselves in the built environment to address place, personalization, territory, and wayfinding, down to smaller details, including strategically framed exterior views. Unlike traditional day schools, this demographic is tasked with the extremely difficult goal to restructure their consciousness from the inside out, in addition to the baseline academic requirements. As the largest physical teaching tool, the school itself assists the sensitive students and hardworking staff in their transitional journey

Competition Without Chaos

California heralded the New Year with a wave of rolling blackouts, spiraling wholesale electricity prices, and at least one utility bankruptcy. California, which symbolizes the electronic age and represents an eighth of the U.S. economy and its population, faces electricity supply issues not seen since the Great Depression and the collapse of the great utility holding companies. To what extent is California the bellwether for the restructured electric industry in the United States? We do not believe that the recent crisis in California is a signal that competition and deregulation have failed. Indeed, it remains our firm belief that market-oriented restructuring of the electric industry remains the best opportunity to provide consumer benefits and to develop reliable new sources of supply. After all, a major impetus for introducing competition into the generation and marketing of electricity has been the previous failures in long-term planning decisions made by public utilities and their regulators. The regulated monopoly regime simply did not provide the correct economic incentives for a company to provide electric service efficiently. To what extent can other states that have restructured their electric industries expect to see California-like dramatic sustained price increases and supply shortages resulting in rolling blackouts? The root cause of California's problems was its long-term failure to build generating plants during the most sustained economic boom in the state's history. California's most significant restructuring problem was also a local issue. The California restructuring law required utilities collecting stranded costs to retain fixed price obligations to retail customers, while preventing them from hedging their price risk in the wholesale market by entering into long-term supply contracts. The California market design flaws have been avoided in the restructuring legislation enacted by the twenty-four states and the District of Columbia that have restructured electricity markets. Among these states are Pennsylvania and Illinois, the states where Exelon conducts public utility businesses. The restructuring efforts in these other states are generally yielding results quite different from those in California and demonstrate that thoughtful, market-oriented, evolutionary restructuring can work well for all parties. This is not a reason, however, for complacency. Government agencies, utilities and all market stakeholders must work hard to make sure this answer remains valid a few years hence. This work includes establishing appropriate pricing and incentives to encourage the building of new supply and the development of demand-side management programs; establishing regional transmission organizations in order to support the expansion of and appropriate pricing for transmission; establishing appropriate rules and pricing regarding the utilities provider of last resort or default supply obligation. The default supply issue is one of the most significant challenges to the transition to competition. If the delivery companies retain primary responsibility for arranging supply and thus lock up most of the generation sources, the result is reliable service and stable rates for customers. However, new market entrants' access to supply sources will be limited and at high prices, making it difficult for them to compete. To resolve this dilemma, we propose a bifurcated approach to default service offerings and pricing. For large customers, who have the most desirable service characteristics to competitive suppliers and thus more opportunity to hedge their price risk, the utilities' only default service obligation would be unbundled energy at a market price. For mass market customers, who lack hedging ability because of limited, if any, market development, the utilities would provide a fixed price, multi-year energy supply offering. The price for both offerings must include a risk premium adequate to compensate the utility for the risk it assumes and to avoid rates that are too low to allow alternative suppliers to compete. We believe our default supply resolution will achieve the competing goals of price stability, reliability, and the development of a mature competitive market. The California experience is not an accident or the product of bad luck. It is the product of choices, long-term choices about siting generation and transmission, and the more recent choice of a market design that imposed asymmetric risks on utilities to the ultimate detriment of all. If other states make similar choices, similar consequences can be expected to follow. In short, the California experience is no reason to reject restructuring; it is rather a forceful lesson on the importance of doing it right.

Recent progress in biodegradable polymers and nanocomposite-based packaging materials for sustainable environment

Plastic-based materials are frequently used in packaging and can be seen universally in both the developed and developing societies. At present, most of the currently used food packaging materials are nondegradable and are creating serious environmental problems. New technologies are being explored and developed to study the complex interaction between the food packaging materials and food. For example, nanocomposite of cellulose constitutes environmentally friendly packaging, which is easily recycled by combustion and requires low power consumption in production. There are several such biodegradable materials which are available at a low price, have good mechanical properties and allow disposal in the soil. This is advantageous because biological degradation produces only carbon dioxide, water, and inorganic compounds to name a few. It has also been discovered that biodegradable plastics made of such materials can be disposed of together with organic waste. The widespread use of biopolymers in the place of standard plastics would help to reduce the weight of waste. Therefore, biodegradable materials take part in the natural cycle “from nature to nature” and play an important role for environmental sustainability. So, in this article, we briefly summarize the different characteristic of biodegradable polymers being used in food packaging applications

A Demonstration of using Partnerships and Private Lands Conservation to Evaluate Livestock Grazing as a Management Tool for Greater Sage Grouse in Central Montana

Partnerships across agencies and land ownerships established to maintain wildlife-compatible “working landscapes” are critical for conserving and managing wildlife in the West.  Preliminary results from the first three years of a 10-yr study in central Montana demonstrate this management approach.  We are evaluating prescribed grazing systems implemented by NRCS’s Sage Grouse Initiative (SGI) that are designed to improve hiding cover and food availability for Greater sage grouse (Centrocercus urophasianus) during critical life stages via voluntary, incentive-based modifications of livestock grazing management.  Extensive vegetation sampling across 8 SGI-enrolled ranches and 20 non-enrolled ranches in 2013 revealed significant increases in residual grass height, live grass height, and herbaceous vegetation cover on SGI-enrolled lands. In 2011-2013, we monitored adult female sage-grouse and chicks with radiotelemetry to measure vital rates and habitat use. Annual hen survival ranged from 57-74 percent, nest success ranged from 12-61 percent, and chick survival ranged from 9-23 percent.  Using an information theoretic approach in program MARK, the top-ranked nest success model showed that grass height was positively correlated with nest success.   During late nesting to early brood rearing periods of 2012 and 2013 we used pitfall traps to collected ground-dwelling arthropods from cattle grazed and rest-rotation phase pastures enrolled in the SGI program. Collected arthropods were identified and appropriate specimens were classified as sage grouse chick food items. During both years of study, food item catches were greatest (P < 0.03) in rested versus grazed pastures indicating that strategic pasture rest may increase the availability of sage grouse chick food resources

Non-Hodgkin lymphoma response evaluation with MRI texture classification

<p>Abstract</p> <p>Background</p> <p>To show magnetic resonance imaging (MRI) texture appearance change in non-Hodgkin lymphoma (NHL) during treatment with response controlled by quantitative volume analysis.</p> <p>Methods</p> <p>A total of 19 patients having NHL with an evaluable lymphoma lesion were scanned at three imaging timepoints with 1.5T device during clinical treatment evaluation. Texture characteristics of images were analyzed and classified with MaZda application and statistical tests.</p> <p>Results</p> <p>NHL tissue MRI texture imaged before treatment and under chemotherapy was classified within several subgroups, showing best discrimination with 96% correct classification in non-linear discriminant analysis of T2-weighted images.</p> <p>Texture parameters of MRI data were successfully tested with statistical tests to assess the impact of the separability of the parameters in evaluating chemotherapy response in lymphoma tissue.</p> <p>Conclusion</p> <p>Texture characteristics of MRI data were classified successfully; this proved texture analysis to be potential quantitative means of representing lymphoma tissue changes during chemotherapy response monitoring.</p

Partial Inhibition of Estrogen-Induced Mammary Carcinogenesis in Rats by Tamoxifen: Balance between Oxidant Stress and Estrogen Responsiveness

Epidemiological and experimental evidences strongly support the role of estrogens in breast tumor development. Both estrogen receptor (ER)-dependent and ER-independent mechanisms are implicated in estrogen-induced breast carcinogenesis. Tamoxifen, a selective estrogen receptor modulator is widely used as chemoprotectant in human breast cancer. It binds to ERs and interferes with normal binding of estrogen to ERs. In the present study, we examined the effect of long-term tamoxifen treatment in the prevention of estrogen-induced breast cancer. Female ACI rats were treated with 17β-estradiol (E2), tamoxifen or with a combination of E2 and tamoxifen for eight months. Tissue levels of oxidative stress markers 8-iso-Prostane F2α (8-isoPGF2α), superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase, and oxidative DNA damage marker 8-hydroxydeoxyguanosine (8-OHdG) were quantified in the mammary tissues of all the treatment groups and compared with age-matched controls. Levels of tamoxifen metabolizing enzymes cytochrome P450s as well as estrogen responsive genes were also quantified. At necropsy, breast tumors were detected in 44% of rats co-treated with tamoxifen+E2. No tumors were detected in the sham or tamoxifen only treatment groups whereas in the E2 only treatment group, the tumor incidence was 82%. Co-treatment with tamoxifen decreased GPx and catalase levels; did not completely inhibit E2-mediated oxidative DNA damage and estrogen-responsive genes monoamine oxygenase B1 (MaoB1) and cell death inducing DFF45 like effector C (Cidec) but differentially affected the levels of tamoxifen metabolizing enzymes. In summary, our studies suggest that although tamoxifen treatment inhibits estrogen-induced breast tumor development and increases the latency of tumor development, it does not completely abrogate breast tumor development in a rat model of estrogen-induced breast cancer. The inability of tamoxifen to completely inhibit E2-induced breast carcinogenesis may be because of increased estrogen-mediated oxidant burden