Developing a Lightweight Rock-Paper-Scissors Framework for Human-Robot Collaborative Gaming

© 2013 IEEE. We present a novel implementation of a Rock-Paper-Scissors (RPS) game interaction with a social robot. The framework is tailored to be computationally lightweight, as well as entertaining and visually appealing through collaboration with designers and animators. The fundamental gesture recognition pipeline employs a Leap motion device and two separate machine learning architectures to evaluate kinematic hand data on-the-fly. The first architecture is used to recognize and segment human motion activity in order to initialize the RPS play, and the second architecture is used to classify hand gestures into rock, paper or scissors. The employed tabletop robot interacts in the RPS play through unique animated gestural movements and vocalizations designed by animators which communicate the robot's choices as well as cognitive reflection on winning, losing and draw states. Performance of both learning architectures is carefully evaluated with respect to accuracy, reliability and run time performance under different feature and classifier types. Moreover, we assess our system during an interactive RPS play between robot and human. Experimental results show that the proposed system is robust to user variations and play style in real environment conditions. As such, it offers a powerful application for the subsequent exploration of social human-machine interaction

Promoção da saúde e seu alcance biopolítico: o discurso sanitário da sociedade contemporânea

O conceito de Promoção da Saúde vem sendo trabalhado por diferentes atores sociais ao longo dos últimos vinte anos e publicações teóricas e pesquisas têm contribuído para proceder à delimitação dos conceitos e práticas nesta área; em alguns casos, partindo de um ponto de vista crítico com relação ao seu arcabouço teórico-conceitual. Este artigo analisa o discurso sanitário contemporâneo no contexto das políticas de promoção da saúde; identificando essas políticas como estratégias reguladas, sobretudo, pela manutenção do projeto biopolítico de controle social dos corpos. Reconhecemos, então, o atual discurso da Promoção da Saúde como um dispositivo de regulação da vida que se define, de certo modo, pela continuidade do projeto biopolítico moderno tal como descrito por Foucault. Porém, mais do que isso, a promoção da saúde apresenta-se como uma forma de controle e regulação dos corpos através de uma inflexão sobre a responsabilidade individual na administração da vida. Desta forma, o discurso da promoção da saúde ajusta-se à perspectiva das doutrinas do fim do Estado de Bem-Estar Social; constituindo-se como um projeto de autonomização dos indivíduos através da atribuição de responsabilidade sobre seus próprios cuidados. Nosso olhar sobre o quadro conceitual da promoção da saúde busca, assim, inserir-se no atual debate travado no campo da saúde coletiva, sublinhando as transformações nas concepções de saúde e doença, seu compromisso com o fim do Estado de proteção e seus efeitos nas sociabilidades

Autoimmune cirrhosis treated by liver transplantation using the right hepatic lobe from a living related donor

peer reviewedThe authors describe the case of a 17-year-old girl who suffered from end-stage liver failure due to chronic autoimmune hepatitis. Liver failure was complicated by severe portal hypertension, hypersplenism and refractory ascites. Liver transplantation was indicated. She was listed for cadaveric whole liver transplantation, but her infrequent blood group (B) increased waiting time. Her condition deteriorated to Child C liver failure and living related liver transplant was considered. Her father was compatible and proposed himself for donation. Right lobe procurement was decided in order to provide sufficient liver mass. No transfusion of red cells, platelets, or fresh frozen plasma was used either in the donor or the recipient. Both recipient and donor left the ward at postoperative day 14, without complication. They were both asymptomatic and with normal liver tests at one year follow-up. Living related liver transplantation using the right lobe may offer an alternative to liver transplant candidates in this period of organ donor shortage

Clinical Case of the Month. Autoimmune Cirrhosis Treated by Liver Transplantation Using the Right Hepatic Lobe from a Living Related Donor

peer reviewedThe authors describe the case of a 17-year-old girl who suffered from end-stage liver failure due to chronic autoimmune hepatitis. Liver failure was complicated by severe portal hypertension, hypersplenism and refractory ascites. Liver transplantation was indicated. She was listed for cadaveric whole liver transplantation, but her infrequent blood group (B) increased waiting time. Her condition deteriorated to Child C liver failure and living related liver transplant was considered. Her father was compatible and proposed himself for donation. Right lobe procurement was decided in order to provide sufficient liver mass. No transfusion of red cells, platelets, or fresh frozen plasma was used either in the donor or the recipient. Both recipient and donor left the ward at postoperative day 14, without complication. They were both asymptomatic and with normal liver tests at one year follow-up. Living related liver transplantation using the right lobe may offer an alternative to liver transplant candidates in this period of organ donor shortage

Determining the neurotransmitter concentration profile at active synapses

Establishing the temporal and concentration profiles of neurotransmitters during synaptic release is an essential step towards understanding the basic properties of inter-neuronal communication in the central nervous system. A variety of ingenious attempts has been made to gain insights into this process, but the general inaccessibility of central synapses, intrinsic limitations of the techniques used, and natural variety of different synaptic environments have hindered a comprehensive description of this fundamental phenomenon. Here, we describe a number of experimental and theoretical findings that has been instrumental for advancing our knowledge of various features of neurotransmitter release, as well as newly developed tools that could overcome some limits of traditional pharmacological approaches and bring new impetus to the description of the complex mechanisms of synaptic transmission

Proteolysis of proBDNF Is a Key Regulator in the Formation of Memory

It is essential to understand the molecular processes underlying long-term memory to provide therapeutic targets of aberrant memory that produce pathological behaviour in humans. Under conditions of recall, fully-consolidated memories can undergo reconsolidation or extinction. These retrieval-mediated memory processes may rely on distinct molecular processes. The cellular mechanisms initiating the signature molecular events are not known. Using infusions of protein synthesis inhibitors, antisense oligonucleotide targeting brain-derived neurotrophic factor (BDNF) mRNA or tPA-STOP (an inhibitor of the proteolysis of BDNF protein) into the hippocampus of the awake rat, we show that acquisition and extinction of contextual fear memory depended on the increased and decreased proteolysis of proBDNF (precursor BDNF) in the hippocampus, respectively. Conditions of retrieval that are known to initiate the reconsolidation of contextual fear memory, a BDNF-independent memory process, were not correlated with altered proBDNF cleavage. Thus, the processing of BDNF was associated with the acquisition of new information and the updating of information about a salient stimulus. Furthermore, the differential requirement for the processing of proBDNF by tPA in distinct memory processes suggest that the molecular events actively engaged to support the storage and/or the successful retrieval of memory depends on the integration of ongoing experience with past learning

Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour

Feedforward excitatory and inhibitory circuits regulate cerebellar output, but how these circuits interact to shape the somatodendritic excitability of Purkinje cells during motor behaviour remains unresolved. Here we perform dendritic and somatic patch-clamp recordings in vivo combined with optogenetic silencing of interneurons to investigate how dendritic excitation and inhibition generates bidirectional (that is, increased or decreased) Purkinje cell output during self-paced locomotion. We find that granule cells generate a sustained depolarization of Purkinje cell dendrites during movement, which is counterbalanced by variable levels of feedforward inhibition from local interneurons. Subtle differences in the dendritic excitation–inhibition balance generate robust, bidirectional changes in simple spike (SSp) output. Disrupting this balance by selectively silencing molecular layer interneurons results in unidirectional firing rate changes, increased SSp regularity and disrupted locomotor behaviour. Our findings provide a mechanistic understanding of how feedforward excitatory and inhibitory circuits shape Purkinje cell output during motor behaviour

Gestantes em situação de rua no município de Santos, SP: reflexões e desafios para as políticas públicas

O estudo teve como objetivo investigar o cotidiano de gestantes em situação de rua e sua relação com as políticas públicas na cidade de Santos, litoral do Estado de São Paulo. A coleta de dados foi feita através do registro e estudo de narrativas de memórias de vida. A análise deu-se pelo agrupamento temático de trechos das narrativas, sendo identificadas quatro principais categorias: vida na rua; cuidado e gestação; projetos futuros; e rede pública de serviços. As narrativas revelam mulheres com capacidade criativa para desejar uma vida melhor a partir da possibilidade de ter um filho. Entretanto, a condição social em que vivem, envolvendo a luta diária pela sobrevivência e, em alguns casos, a dependência química dificultam o planejamento de estratégias que transformem o desejo em um projeto de vida. Dessa forma, na maioria das vezes perdem a guarda de seus filhos. Embora conheçam os serviços públicos, quase sempre os acessam apenas em casos de urgência. Não se identificaram na rede de serviços assistenciais - pública e do terceiro setor - programas focados na questão da gestante em situação de rua, ainda que o Brasil já viva, atualmente, histórias de famílias que têm a situação de rua como experiência intergeracional. Os resultados apontam para a necessidade de constituição de políticas intersetoriais, voltadas para gestantes em situação de rua