8 research outputs found
Abandoned projects-implication on the strength of exposed steel and concrete in the Southern region of Nigeria
This research is centered on the investigation of the implication of abandonment on the strength of exposed steel and concrete in an abandoned project; as most abandoned project are continued without due consideration to the current strength of the structural members, which may lead to eventual collapse, if the structural members have failed in strength. Six abandoned project sites were investigated: three in Port Harcourt, Rivers state and the other three in Lagos, Lagos state, Nigeria. Thus limiting the investigation to Southern region of Nigeria where the temperature ranges between 23°C and 32°C and precipitation/rainfall ranged between 36mm and 410mm.The Periods of the abandonment ranges from three to thirty-five years. All structural members were cast in-situ. Visual inspections were carried out on site, rebound hammer test was done, concrete samples were cored and steel reinforcement bars were cut from site. Laboratory test and analysis were carried on te cored samples as well as tensile test carried out on the steel samples. Data obtained from both field and laboratory analysis, were analyzed using Excel regression analysis and a model was obtained to help determine the estimated steel strength of exposed steel reinforcement bars after a period of abandonment in the region considered.Keywords: abandonment, concrete, steel, compressive strength, tensile strengt
Dietary Effect of .ALPHA.-Tocopherol and Tocotrienols on Lipid Metabolism and Immune Function of Aged Sprague-Dawley Rats.
T1G1 Bladder Cancer: Prognosis for this Rare Pathological Diagnosis Within the Non-muscle-invasive Bladder Cancer Spectrum
BACKGROUND: The pathological existence and clinical consequence of stage T1 grade 1 (T1G1) bladder cancer are the subject of debate. Even though the diagnosis of T1G1 is controversial, several reports have consistently found a prevalence of 2-6% G1 in their T1 series. However, it remains unclear if T1G1 carcinomas have added value as a separate category to predict prognosis within the non-muscle-invasive bladder cancer (NMIBC) spectrum. OBJECTIVE: To evaluate the prognostic value of T1G1 carcinomas compared to TaG1 and T1G2 carcinomas within the NMIBC spectrum. DESIGN, SETTING, AND PARTICIPANTS: Individual patient data for 5170 primary Ta and T1 bladder tumors from 17 hospitals in Europe and Canada were analyzed. Transurethral resection (TUR) was performed between 1990 and 2018. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Time to recurrence and progression were analyzed using cumulative incidence functions, log-rank tests, and multivariable Cox regression models stratified by institution. RESULTS AND LIMITATIONS: T1G1 represented 1.9% (99/5170) of all carcinomas and 5.3% (99/1859) of T1 carcinomas. According to primary TUR dates, the proportion of T1G1 varied between 0.9% and 3.5% per year, with similar percentages in the early and later calendar years. We found no difference in time to recurrence between T1G1 and TaG1 (p = 0.91) or between T1G1 and T1G2 (p = 0.30). Time to progression significantly differed between TaG1 and T1G1 (p < 0.001) but not between T1G1 and T1G2 (p = 0.30). Multivariable analyses for recurrence and progression showed similar results. CONCLUSIONS: The relative prevalence of T1G1 diagnosis was low and remained constant over the past three decades. Time to recurrence of T1G1 NMIBC was comparable to that for other stage/grade NMIBC combinations. Time to progression of T1G1 NMIBC was comparable to that for T1G2 but not for TaG1, suggesting that treatment and surveillance of T1G1 carcinomas should be more like the approaches for T1G2 NMIBC in accordance with the intermediate and/or high risk categories of the European Association of Urology NMIBC guidelines. PATIENT SUMMARY: Although rare, stage T1 grade 1 (T1G1) bladder cancer is still diagnosed in daily clinical practice. Using individual patient data from 17 centers in Europe and Canada, we found that time to progression of T1G1 cancer was comparable to that for T1G2 but not TaG1 cancer. Therefore, our results suggest that primary T1G1 bladder cancers should be managed with more aggressive treatment and more frequent follow-up than for low-risk bladder cancer