Risk-sharing in Rural Pakistan

Risk-sharing is a fundamental form of economic behaviour. It can occur through formal insurance markets, informal family arrangements, community support, legal institutions (such as bankruptcy), or government tax-transfer programmes. Whatever the mechanism used to share risk, the extent of risk mitigation can greatly influence the welfare of all members of society. Understanding the degree of risk-pooling in society is important for policy-makers, since insufficient risk pooling may provide a basis for government intervention. Alternatively, if risks are being pooled adequately without the help of the government, government risk-sharing may be redundant. This study explores the implications of the risk-sharing model, namely, that households which pool risks, either through formal markets or informal personal arrangements, experience correlated changes in their consumption through time. It conducts tests of within-village, across-village, within-district, and across-district risksharing using a new Pakistani panel data set—the Pakistan Food Security Management Survey—collected by the International Food Policy Research Institute (IFPRI), Washington, D. C. Unlike studies for other Less Developed Countries (LDCs), these tests find very little or almost no evidence of risk-sharing among unrelated individuals within- and across-villages in the rural sector of Pakistan.

Time to Talk: The Benefits of Therapeutic Conversations in Supporting Young People With Sensory/Physical and Medical Disabilities

The health and emotional wellbeing of young people have increasingly come under the spotlight over the years. This is particularly so for young people who have sensory/physical or medical needs as, along with the pressures of adolescence and growing up, they also face many barriers and issues to do with their disabilities. However, there has not been much written about in terms of targeted emotional support and interventions around emotional wellbeing for this population. In light of this gap, the Educational Psychology Service of Tower Hamlets and Public Health became involved in a project called “Time To Talk”. This offered thirty-six young people with sensory/physical/medical needs in seven local secondary schools a chance to participate in a counselling based intervention involving therapeutic conversations. Various approaches taken from solution-focused thinking, motivational interviewing and cognitive behaviour therapy were used to guide the conversations. The intervention was short term, offering young people up to six sessions, each for a maximum of 50 minutes. Evaluation of the project was through a mixture of pre- and post-scaling before and after the intervention as well as qualitative information from comments the young people made. Overall, there was a generally positive impact, with many young people feeling better able to manage their situations and decreasing in their concerns and generally feeling well listened to. Their schools also acknowledged some positive changes and valued the input. In conclusion, the project highlighted a number of important themes to emerge from the conversations with the young people such as: wanting to have independence and autonomy, transition and future aspirations, coping with anxiety and stress and relationship issues. The project also demonstrates how partnerships between the Educational Psychology service and different commissioning bodies can lead to creative and imaginative ways of working. After all, educational psychologists can be well placed to offer early interventions for emotional wellbeing before situations reach crisis point, due to their psychological training and experience of working with young people and community and school settings

Health professional students’ perceptions regarding their role in tobacco control: findings from the Global Health Professional Students Survey, Pakistan, 2011

Background: An important way of reducing tobacco use is to train the health professional (HP) students to assist in tobacco cessation by educating patients and public. In order to shape their thoughts for the desired role, it is vital to understand their existing perceptions regarding HP’s role in tobacco control. Thus, the aim of our study was to find out the perceptions of Pakistani HP students regarding their future role in tobacco control, and examine factors associated with negative perceptions.<p></p> Methods: Secondary data analysis of the Global Health Professional Students Survey, Pakistan, 2011 was performed. Study population included 3445 health professional students in third year of graduate level programs. The dependent variable (perceptions of HP students), was developed using four questions from the survey. Students who did not regard HP’s role in tobacco control were labeled as having negative perceptions. Logistic regression analyses were conducted to analyze association between HP students’ perceptions and various socio-demographic, attitudinal and knowledge related factors; and were reported as adjusted odds ratios with 95% confidence interval.<p></p> Results: We found that 44.8% (n = 1542) of students do not regard HPs as role model for their patients and public, and perceive that HPs do not play an important part in patient’s quitting tobacco use. These negative perceptions were associated with male sex (OR = 1.25, 95% CI 1.02 – 1.53, p value 0.028), and poor knowledge about tobacco cessation techniques (OR = 1.32, 95% CI 1.12 – 1.55, p value < 0.001). Negative perceptions were also associated with their attitudes towards ban on: tobacco advertisements (OR = 1.67, 95% CI 1.13 – 2.48, p value 0.010); and tobacco use at public places (OR = 1.60, 95% CI 1.26 – 2.03, p value < 0.001).<p></p> Conclusion: The role of HPs for tobacco control is fairly under-perceived by HP students, and the undesired negative perceptions are associated with male sex, poor knowledge about tobacco use cessation techniques and negative attitudes towards legislative control. A comprehensive approach, focusing on these aspects should be adopted to train HPs, in order to utilize them as an effective manpower for tobacco control

Antecedents of organizational identification: implications for employee performance

Purpose This study aims to investigate the impact of three determinants of organizational identification (OID) on employee performance (EP) in the context of private business institutions. Design/methodology/approach A sample of 175 permanent faculty members from four top universities in Karachi, Pakistan, was interviewed using a five-point Likert scale questionnaire. The data were inserted in SPSS 22 and SmartPLS v 3.2 for performing the analysis. Findings Results of the study showed a significant effect in perceived supervisor support on OID; OID; job satisfaction and EP; and mediating relationship. Conversely, an insignificant effect was observed in workplace incivility. Research limitations/implications It is highly recommended that organizations work on the areas that lead to enhancing their employees’ performance. Also, human resource should create a healthy culture that promotes initiatives, open-door policies and discourages power distance. Lastly, one of the key responsibilities of management is to strengthen their OID because employees are more likely to identify with their supervisors if they invest in the organizations they work for. Practical implications This study will help strengthen the relationship between supervisors and university employees. It will guide the supervisors to acknowledge and appreciate the efforts of their subordinates and develop recreational policies and employee engagement activities. In addition, it will help develop a conducive environment and enhance the quality of education in the university and the society. Originality/value Understanding the determinants of OID on EP in the educational context is very important as it enhances the quality of EP and the overall quality of education of the institution

Paroxetine is Pro-inflammatory in Human Brain Microvascular Endothelial Cells

BACKGROUND: Paroxetine is an antidepressant that is widely used. However, Paroxetine possesses anticholinergic properties which may contribute to cognitive decline in older adults. Surprisingly, the mechanisms of the cognitive decline of anticholinergic drugs in older adults remains elusive. A hypothesis is that a loss of cholinergic signaling is pro-inflammatory in the brain. We designed experiments to determine if Paroxetine is pro-inflammatory in Normal Human Brain Microvascular Endothelial Cells (NHBMECs). METHOD: NHBMECs were grown at 5% CO2, 37C and 95% relative humidity until 90% confluent. NHBMECs were treated with the RNA free water as control, Paroxetine as 1.67x 10 4 mM/mol, IL1B 2ng/ml for 24 hours. RNA was isolated, converted into CDNA, and gene expression determined via RT-PCR. Statistical analysis was performed via ANOVA and post-hoc Tukey’s with a significant p-value \u3c 0.05. Experiments were completed on 10-04-19. The mRNA expression studies were performed on 11-01-19. RESULTS: NHBMECs exposed to Paroxetine for 24 hours demonstrated elevated expression of CCL2 and CXCL5. NHBMECs exposed to Paroxetine + IL1B demonstrated synergistic elevations in CCL2 and CXCL5. CONCLUSION: Our result suggests that Paroxetine may have pro-inflammatory properties within this subset of human brain cells. Therefore, our preliminary data suggests the possibility of pathological pro- inflammatory mechanisms associated with Paroxetine. Further evaluation of different populations of normal human brain cells are warranted.https://scholarscompass.vcu.edu/gradposters/1096/thumbnail.jp

Can early orthotic support and physical Therapy improve the functional level and Decrease rate of surgical interventions In spastic cerebral palsy?

cerebral palsy is a disorder of movement and posture that results from a non progressive lesion of brain within 3 years of age. To determine the role of early orthotics and physical therapy in improving the functional status and in decreasing the rate of surgical interventions in management of spastic diplegic cerebral palsy child

Prevalence and determinants of susceptibility to cigarette smoking among school students in Pakistan: secondary analysis of Global Youth Tobacco Survey

Background: Susceptibility to smoke has been recognized as a strong predictor of smoking experimentation and taking up regular smoking habit. The identification of smoking susceptible individuals and its determinants is important in the efforts to reduce future smoking prevalence. The aims of this study are to estimate prevalence of susceptibility to smoke among adolescents, and identify factors associated with it.<p></p> Methods: Cross sectional data was obtained from Global Youth Tobacco Survey conducted in three cities of Pakistan in year 2004. Study population consisted of students in grades, 8th, 9th, and 10th; aged 13 to 15 years. Secondary analysis using univariate and multivariate logistic regression analyses were performed to estimate the associations between smoking susceptibility and co-variates. Descriptive statistics were reported in proportions, and adjusted odds ratios with 95% confidence interval were used to report logistic regression analyses.<p></p> Results: Approximately 12% of nonsmoking students were found susceptible to smoking. Students, who were females (OR = 1.53, 95% CI [1.24-1.89]); whose parents (OR = 1.64, 95% CI [1.35-1.99]); or close friend smoked (OR = 2.77, 95% CI [2.27- 3.40]) were more susceptible to cigarette smoking. Students who had good knowledge about harmful effects of smoking (OR = 0.54, 95% CI [0.43-0.69]); and had access to anti-smoking media (OR = 0.73, 95% CI [0.59-0.89]) were less likely to be susceptible to smoking.<p></p> Conclusion: Students who were females, had smoking parents, friends or exposure to newspaper/magazines cigarette marketing, were more susceptible to cigarette smoking among Pakistani adolescents. While knowledge of harmful effects of smoking and access to anti-smoking media served as protective factors against susceptibility to smoking.<p></p&gt

Metabolomics Investigation of Glyceollins by On-Line Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry and Fungal Metabolite Identification by Thermal Desorption Analysis Coupled with Gas Chromatography-Mass Spectrometry

Metabolomics is an emerging field that entails the detailed characterization of the ensemble of metabolites produced by living organisms; subfields include drug metabolism and natural environmental toxin production. The first part of the dissertation pursued metabolism of glyceollins, i.e., isoflavones produced by soybeans, that are potential cancer therapy agents. In vivo glyceollin metabolites produced in rats were investigated by on-line Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry. An odd-electron fragment ion at m/z 148, formed in violation of the even-electron rule, and diagnostic of the glyceollin backbone, was discovered. Based on this finding, a negative mode precursor ion scanning method was developed to screen for glyceollins and their metabolites from biological samples. Products of both Phase I and Phase II metabolism were identified, none of which have been previously reported. Sulfated metabolites were confirmed by accurate mass measurement, while glucuronide conjugation was confirmed by enzyme-assisted glucuronidation by rat liver microsomes. Intact GSH-glyceollin conjugates were not observed, but breakdown products of the GSH pathway, i.e., cysteinylglyceine, cysteine, and acetylated cysteine, were identified as conjugates of oxygenated glyceollins. The identification of GSH by-product conjugates was confirmed in product ion spectra acquired in the negative mode (where peptide anions, and glyceollin-bearing cleaved peptide portions were observed), as well as in the positive mode (where intact oxygenated glyceollin fragments appeared without the initially-present peptide portion). Mass spectral evidence strongly supports a metabolic pathway involving initial epoxidation of glyceollins followed by GSH addition at the epoxidation site. The second part of the dissertation undertook the investigation of secondary metabolites called microbial volatile organic compounds (MVOCs) produced by fungi (mold) that have been reported to have adverse human health effects. MVOCs were collected onto different sorbent materials and analyzed by Thermal Desorption Analysis coupled with on-line Gas Chromatography-Mass Spectrometry. Fungal MVOCs were characterized from various simulated flooding conditions (brackish, freshwater, and saltwater) and different substrates (nutrient rich vs. low nutrient) to determine diagnostic MVOCs. Ten fungi from simulated environments were identified by genetic sequencing. Cladosporium sp. and Chaetomium sp. were cultivated and their emitted MVOCs, 3-furaldehyde and 3-(4-hydroxy-3-methoxyphenyl)-2-propenal, were proposed as diagnostic indicators of these fungi

FOSTERING INTERNATIONAL MINDEDNESS IN INTERNATIONAL BACCALAUREATE CLASSROOMS: A CASE STUDY OF TWO TEACHERS

International Mindedness is central to the mission of International Baccalaureate (IB) education and may be defined as a frame of mind enabling a person to get rid of prejudices of self and embrace a greater sense of the other. Through this study, I analyzed how International Mindedness (IM) is taught in a high school in the Western U.S. and prepared some suggestions for teachers in my country of origin (Pakistan). In this research, I studied three attributes of IM: multilingualism, intercultural understanding and global engagement. Studying IM was significant because it may address the problem of closed-mindedness in Pakistan and may cultivate in learners the ability to belong to the whole world and respect the whole of humanity as they respect themselves. In my study, I have followed qualitative case study design to understand how two IB teachers incorporated the idea of IM in their pedagogy. Qualitative case study design was an appropriate method for this study because it permitted an in-depth focus on issues to understand participants’ perspectives. Participants were selected based on purposeful, convenient sampling in order to gather data from teachers in an IB school. Thematic analysis was done with the qualitative data. Deductive data analysis was followed to identify an educational process and attribute meaning to the texts. Results were generated after triangulation of data gathered through observations, semi-structured interviews, and teaching materials from teachers A and B. Through the findings, it is highlighted that teachers consider global engagement, intercultural understanding, and multilingualism closely associated with fostering IM in their classes

Economic Growth and Child Poverty Reduction in Bangladesh and China

This paper analyzes child poverty in Bangladesh and China during periods of rapid economic growth in both countries. It compares the extent as well as profile of child poverty in both countries. Comparisons on the extent of child poverty, over time and across countries, are made using a decomposition framework attributing child poverty differences to differences in the three components mean child income, demographic circumstances and the distribution of child income. Child poverty is found to be more extensive in Bangladesh than in China, and is very much a problem for rural children in both countries. The results show that economic growth can reduce child poverty but does not do so always. For understanding changes over time and across countries in the extent of child poverty, it can be necessary to also consider changes/differences in the distribution of child income as well as in the demographic composition.Bangladesh, economic growth, child poverty, China